SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bx9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQB_A_RTLA185_0
(RETINOL-BINDING
PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 398
VAL A 376
TYR A 428
LEU A 409
GLN A 413
None
1.30A 1aqbA-4bx9A:
undetectable
1aqbA-4bx9A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.14A 1c9sA-4bx9A:
undetectable
1c9sK-4bx9A:
undetectable
1c9sA-4bx9A:
7.91
1c9sK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 1c9sA-4bx9A:
undetectable
1c9sB-4bx9A:
undetectable
1c9sA-4bx9A:
7.91
1c9sB-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 1c9sB-4bx9A:
undetectable
1c9sC-4bx9A:
undetectable
1c9sB-4bx9A:
7.91
1c9sC-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 1c9sC-4bx9A:
undetectable
1c9sD-4bx9A:
undetectable
1c9sC-4bx9A:
7.91
1c9sD-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.15A 1c9sD-4bx9A:
undetectable
1c9sE-4bx9A:
undetectable
1c9sD-4bx9A:
7.91
1c9sE-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 1c9sE-4bx9A:
undetectable
1c9sF-4bx9A:
undetectable
1c9sE-4bx9A:
7.91
1c9sF-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 1c9sF-4bx9A:
undetectable
1c9sG-4bx9A:
undetectable
1c9sF-4bx9A:
7.91
1c9sG-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.13A 1c9sG-4bx9A:
undetectable
1c9sH-4bx9A:
undetectable
1c9sG-4bx9A:
7.91
1c9sH-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 1c9sH-4bx9A:
undetectable
1c9sI-4bx9A:
undetectable
1c9sH-4bx9A:
7.91
1c9sI-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 1c9sJ-4bx9A:
undetectable
1c9sK-4bx9A:
undetectable
1c9sJ-4bx9A:
7.91
1c9sK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.15A 1c9sL-4bx9A:
undetectable
1c9sM-4bx9A:
undetectable
1c9sL-4bx9A:
7.91
1c9sM-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.14A 1c9sM-4bx9A:
undetectable
1c9sN-4bx9A:
undetectable
1c9sM-4bx9A:
7.91
1c9sN-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 1c9sN-4bx9A:
undetectable
1c9sO-4bx9A:
undetectable
1c9sN-4bx9A:
7.91
1c9sO-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 1c9sO-4bx9A:
undetectable
1c9sP-4bx9A:
undetectable
1c9sO-4bx9A:
7.91
1c9sP-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.15A 1c9sP-4bx9A:
undetectable
1c9sQ-4bx9A:
undetectable
1c9sP-4bx9A:
7.91
1c9sQ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 1c9sQ-4bx9A:
undetectable
1c9sR-4bx9A:
undetectable
1c9sQ-4bx9A:
7.91
1c9sR-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 1c9sS-4bx9A:
undetectable
1c9sT-4bx9A:
undetectable
1c9sS-4bx9A:
7.91
1c9sT-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.13A 1c9sL-4bx9A:
undetectable
1c9sV-4bx9A:
undetectable
1c9sL-4bx9A:
7.91
1c9sV-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 ILE A 558
SER A 259
HIS A   4
LEU A   5
LEU A  48
None
1.15A 1fm6X-4bx9A:
undetectable
1fm6X-4bx9A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 1gtfA-4bx9A:
undetectable
1gtfK-4bx9A:
undetectable
1gtfA-4bx9A:
7.91
1gtfK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 1gtfA-4bx9A:
undetectable
1gtfB-4bx9A:
undetectable
1gtfA-4bx9A:
7.91
1gtfB-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 1gtfB-4bx9A:
undetectable
1gtfC-4bx9A:
undetectable
1gtfB-4bx9A:
7.91
1gtfC-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.13A 1gtfC-4bx9A:
undetectable
1gtfD-4bx9A:
undetectable
1gtfC-4bx9A:
7.91
1gtfD-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.14A 1gtfD-4bx9A:
undetectable
1gtfE-4bx9A:
undetectable
1gtfD-4bx9A:
7.91
1gtfE-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 1gtfE-4bx9A:
undetectable
1gtfF-4bx9A:
undetectable
1gtfE-4bx9A:
7.91
1gtfF-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 1gtfF-4bx9A:
undetectable
1gtfG-4bx9A:
undetectable
1gtfF-4bx9A:
7.91
1gtfG-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 1gtfG-4bx9A:
undetectable
1gtfH-4bx9A:
undetectable
1gtfG-4bx9A:
7.91
1gtfH-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 1gtfH-4bx9A:
undetectable
1gtfI-4bx9A:
undetectable
1gtfH-4bx9A:
7.91
1gtfI-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.13A 1gtfI-4bx9A:
undetectable
1gtfJ-4bx9A:
undetectable
1gtfI-4bx9A:
7.91
1gtfJ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 1gtfJ-4bx9A:
undetectable
1gtfK-4bx9A:
undetectable
1gtfJ-4bx9A:
7.91
1gtfK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.15A 1gtfO-4bx9A:
undetectable
1gtfP-4bx9A:
undetectable
1gtfO-4bx9A:
7.91
1gtfP-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 1gtfP-4bx9A:
undetectable
1gtfQ-4bx9A:
undetectable
1gtfP-4bx9A:
7.91
1gtfQ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 1gtfQ-4bx9A:
undetectable
1gtfR-4bx9A:
undetectable
1gtfQ-4bx9A:
7.91
1gtfR-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.15A 1gtfR-4bx9A:
undetectable
1gtfS-4bx9A:
undetectable
1gtfR-4bx9A:
7.91
1gtfS-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 1gtfS-4bx9A:
undetectable
1gtfT-4bx9A:
undetectable
1gtfS-4bx9A:
7.91
1gtfT-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.14A 1gtfT-4bx9A:
undetectable
1gtfU-4bx9A:
undetectable
1gtfT-4bx9A:
7.91
1gtfU-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.15A 1gtfU-4bx9A:
undetectable
1gtfV-4bx9A:
undetectable
1gtfU-4bx9A:
7.91
1gtfV-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.14A 1gtfL-4bx9A:
undetectable
1gtfV-4bx9A:
undetectable
1gtfL-4bx9A:
7.91
1gtfV-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 1gtnB-4bx9A:
undetectable
1gtnC-4bx9A:
undetectable
1gtnB-4bx9A:
7.91
1gtnC-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.13A 1gtnG-4bx9A:
undetectable
1gtnH-4bx9A:
undetectable
1gtnG-4bx9A:
7.91
1gtnH-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.13A 1gtnH-4bx9A:
undetectable
1gtnI-4bx9A:
undetectable
1gtnH-4bx9A:
7.91
1gtnI-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.16A 1gtnL-4bx9A:
undetectable
1gtnM-4bx9A:
undetectable
1gtnL-4bx9A:
7.91
1gtnM-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.17A 1gtnN-4bx9A:
undetectable
1gtnO-4bx9A:
undetectable
1gtnN-4bx9A:
7.91
1gtnO-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.24A 1gtnR-4bx9A:
undetectable
1gtnS-4bx9A:
undetectable
1gtnR-4bx9A:
7.91
1gtnS-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.21A 1gtnS-4bx9A:
undetectable
1gtnT-4bx9A:
undetectable
1gtnS-4bx9A:
7.91
1gtnT-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.14A 1gtnT-4bx9A:
undetectable
1gtnU-4bx9A:
undetectable
1gtnT-4bx9A:
7.91
1gtnU-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.15A 1gtnU-4bx9A:
undetectable
1gtnV-4bx9A:
undetectable
1gtnU-4bx9A:
7.91
1gtnV-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 PHE A 523
LEU A 227
LEU A 229
LEU A 550
ALA A 176
None
1.05A 1ha2A-4bx9A:
3.3
1ha2A-4bx9A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 ALA A 398
VAL A 376
TYR A 428
LEU A 409
GLN A 413
None
1.29A 1hbpA-4bx9A:
undetectable
1hbpA-4bx9A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 7 GLN A 378
TRP A 473
SER A 486
SER A 490
None
1.23A 1ig3A-4bx9A:
2.3
1ig3B-4bx9A:
2.7
1ig3A-4bx9A:
18.00
1ig3B-4bx9A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 7 GLU A 252
LEU A 249
LEU A 374
GLU A 377
None
1.10A 1linA-4bx9A:
undetectable
1linA-4bx9A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_A_FOLA605_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 LEU A 470
LEU A 502
SER A 504
ILE A 485
LEU A 564
None
1.10A 1qzfA-4bx9A:
undetectable
1qzfA-4bx9A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_B_FOLB609_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 LEU A 470
LEU A 502
SER A 504
ILE A 485
LEU A 564
None
1.10A 1qzfB-4bx9A:
undetectable
1qzfB-4bx9A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_C_FOLC613_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 LEU A 470
LEU A 502
SER A 504
ILE A 485
LEU A 564
None
1.11A 1qzfC-4bx9A:
undetectable
1qzfC-4bx9A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_D_FOLD617_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 LEU A 470
LEU A 502
SER A 504
ILE A 485
LEU A 564
None
1.11A 1qzfD-4bx9A:
undetectable
1qzfD-4bx9A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_E_FOLE621_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 LEU A 470
LEU A 502
SER A 504
ILE A 485
LEU A 564
None
1.11A 1qzfE-4bx9A:
undetectable
1qzfE-4bx9A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.09A 1utdA-4bx9A:
undetectable
1utdB-4bx9A:
undetectable
1utdA-4bx9A:
7.91
1utdB-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.14A 1utdC-4bx9A:
undetectable
1utdD-4bx9A:
undetectable
1utdC-4bx9A:
7.91
1utdD-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 1utdD-4bx9A:
undetectable
1utdE-4bx9A:
undetectable
1utdD-4bx9A:
7.91
1utdE-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.09A 1utdE-4bx9A:
undetectable
1utdF-4bx9A:
undetectable
1utdE-4bx9A:
7.91
1utdF-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.11A 1utdG-4bx9A:
undetectable
1utdH-4bx9A:
undetectable
1utdG-4bx9A:
7.91
1utdH-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.10A 1utdH-4bx9A:
undetectable
1utdI-4bx9A:
undetectable
1utdH-4bx9A:
7.91
1utdI-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 1utdA-4bx9A:
undetectable
1utdK-4bx9A:
undetectable
1utdA-4bx9A:
7.91
1utdK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 1utdM-4bx9A:
undetectable
1utdN-4bx9A:
undetectable
1utdM-4bx9A:
7.91
1utdN-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.11A 1utdN-4bx9A:
undetectable
1utdO-4bx9A:
undetectable
1utdN-4bx9A:
7.91
1utdO-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.17A 1utdQ-4bx9A:
undetectable
1utdR-4bx9A:
undetectable
1utdQ-4bx9A:
7.91
1utdR-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 1utdR-4bx9A:
undetectable
1utdS-4bx9A:
undetectable
1utdR-4bx9A:
7.91
1utdS-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.14A 1utdS-4bx9A:
undetectable
1utdT-4bx9A:
undetectable
1utdS-4bx9A:
7.91
1utdT-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 1utdT-4bx9A:
undetectable
1utdU-4bx9A:
undetectable
1utdT-4bx9A:
7.91
1utdU-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 1utdU-4bx9A:
undetectable
1utdV-4bx9A:
undetectable
1utdU-4bx9A:
7.91
1utdV-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 8 ASP A 372
ASN A 390
GLN A 413
LYS A 405
None
1.10A 2cmlB-4bx9A:
undetectable
2cmlB-4bx9A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 8 ASP A 372
ASN A 390
GLN A 413
LYS A 405
None
1.10A 2cmlD-4bx9A:
undetectable
2cmlD-4bx9A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
3 / 3 LYS A 286
GLY A  44
PRO A  45
None
0.97A 2hreB-4bx9A:
undetectable
2hreB-4bx9A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 LEU A 228
ILE A 576
ILE A 558
ILE A 485
ILE A 547
None
0.84A 2hs1B-4bx9A:
undetectable
2hs1B-4bx9A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 VAL A 477
GLY A 491
SER A 490
LEU A 244
LEU A 374
None
1.25A 2j2pB-4bx9A:
undetectable
2j2pC-4bx9A:
undetectable
2j2pB-4bx9A:
18.57
2j2pC-4bx9A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A
VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 16 HOMOLOG

(Homo
sapiens;
Homo
sapiens)
3 / 3 MET A 592
GLU A 439
ASP C 698
None
1.11A 3a25A-4bx9A:
3.7
3a25A-4bx9A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 16 HOMOLOG

(Homo
sapiens)
3 / 3 ASN C 663
ASP C 656
GLN C 652
None
0.83A 3eeyE-4bx9C:
undetectable
3eeyE-4bx9C:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 7 GLY A 132
PHE A 134
MET A  90
PHE A  81
None
1.07A 3ko0D-4bx9A:
undetectable
3ko0E-4bx9A:
undetectable
3ko0D-4bx9A:
10.52
3ko0E-4bx9A:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 7 TYR A 492
TYR A 489
GLU A 377
PHE A 370
None
1.01A 3ku9B-4bx9A:
undetectable
3ku9B-4bx9A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 ALA A 577
GLY A 552
VAL A 575
ASP A 150
LEU A 182
None
0.89A 3m6vA-4bx9A:
undetectable
3m6vA-4bx9A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 ALA A 577
GLY A 552
VAL A 575
ASP A 150
LEU A 182
None
0.90A 3m6vB-4bx9A:
3.2
3m6vB-4bx9A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 ALA A 577
GLY A 552
VAL A 575
ASP A 150
LEU A 182
None
0.91A 3m6wA-4bx9A:
undetectable
3m6wA-4bx9A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 6 GLN A 243
TYR A 489
PRO A 494
LEU A 237
None
1.32A 3tgvB-4bx9A:
undetectable
3tgvB-4bx9A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 ASP A 363
ILE A 361
VAL A 307
ILE A 299
LEU A 263
None
1.26A 4a84A-4bx9A:
undetectable
4a84A-4bx9A:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 8 ASP A 372
ASN A 390
GLU A 379
ASP A 395
None
1.15A 4gkhD-4bx9A:
undetectable
4gkhD-4bx9A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
3 / 3 ARG A  86
ASP A  91
ASP A 127
None
0.74A 4kicB-4bx9A:
3.1
4kicB-4bx9A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 8 TYR A  41
ARG A  84
ARG A  86
ASP A 168
None
1.21A 4kr4C-4bx9A:
undetectable
4kr4C-4bx9A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
3 / 3 ARG A 137
GLU A 138
PHE A  26
None
0.96A 4kszA-4bx9A:
undetectable
4kszA-4bx9A:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_A_MTXA603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 LEU A 470
LEU A 502
SER A 504
ILE A 485
LEU A 564
None
1.13A 4ky8A-4bx9A:
undetectable
4ky8A-4bx9A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 LEU A 470
LEU A 502
SER A 504
ILE A 485
LEU A 564
None
1.14A 4ky8D-4bx9A:
undetectable
4ky8D-4bx9A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_E_MTXE603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 LEU A 470
LEU A 502
SER A 504
ILE A 485
LEU A 564
None
1.11A 4ky8E-4bx9A:
undetectable
4ky8E-4bx9A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 8 ASP A  39
LEU A  66
ASN A  96
ILE A  93
None
1.09A 4l7iA-4bx9A:
undetectable
4l7iA-4bx9A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
3 / 3 THR A 554
ASN A 303
PHE A 304
None
0.80A 4pd9A-4bx9A:
2.1
4pd9A-4bx9A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_A_MTXA604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 LEU A 470
LEU A 502
SER A 504
ILE A 485
LEU A 564
None
1.18A 4q0dA-4bx9A:
2.4
4q0dA-4bx9A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 LEU A 228
ILE A 576
ILE A 558
ILE A 485
ILE A 547
None
0.90A 4q1xB-4bx9A:
undetectable
4q1xB-4bx9A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 LEU A 228
ILE A 576
ILE A 558
ILE A 485
ILE A 547
None
0.90A 4q1yB-4bx9A:
undetectable
4q1yB-4bx9A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
6 / 11 ALA A 500
LEU A 499
GLU A 557
LEU A 472
ARG A 471
LEU A 470
None
1.49A 4wg0C-4bx9A:
undetectable
4wg0D-4bx9A:
undetectable
4wg0E-4bx9A:
undetectable
4wg0C-4bx9A:
4.64
4wg0D-4bx9A:
4.64
4wg0E-4bx9A:
4.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
6 / 11 ALA A 500
LEU A 499
GLU A 557
LEU A 472
ARG A 471
LEU A 470
None
1.44A 4wg0E-4bx9A:
undetectable
4wg0F-4bx9A:
undetectable
4wg0G-4bx9A:
undetectable
4wg0E-4bx9A:
4.64
4wg0F-4bx9A:
4.64
4wg0G-4bx9A:
4.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 7 THR A 469
LEU A 470
THR A 465
LEU A 518
None
0.96A 4z91F-4bx9A:
4.6
4z91G-4bx9A:
4.4
4z91H-4bx9A:
4.4
4z91I-4bx9A:
4.5
4z91J-4bx9A:
2.1
4z91F-4bx9A:
20.92
4z91G-4bx9A:
20.92
4z91H-4bx9A:
20.92
4z91I-4bx9A:
20.92
4z91J-4bx9A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 4 TYR A 186
GLY A   8
SER A   6
LEU A  12
None
1.37A 5bphC-4bx9A:
undetectable
5bphC-4bx9A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eeuA-4bx9A:
undetectable
5eeuB-4bx9A:
undetectable
5eeuA-4bx9A:
7.91
5eeuB-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eeuB-4bx9A:
undetectable
5eeuC-4bx9A:
undetectable
5eeuB-4bx9A:
7.91
5eeuC-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5eeuC-4bx9A:
undetectable
5eeuD-4bx9A:
undetectable
5eeuC-4bx9A:
7.91
5eeuD-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eeuD-4bx9A:
undetectable
5eeuE-4bx9A:
undetectable
5eeuD-4bx9A:
7.91
5eeuE-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eeuE-4bx9A:
undetectable
5eeuF-4bx9A:
undetectable
5eeuE-4bx9A:
7.91
5eeuF-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eeuF-4bx9A:
undetectable
5eeuG-4bx9A:
undetectable
5eeuF-4bx9A:
7.91
5eeuG-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.08A 5eeuG-4bx9A:
undetectable
5eeuH-4bx9A:
undetectable
5eeuG-4bx9A:
7.91
5eeuH-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eeuH-4bx9A:
undetectable
5eeuI-4bx9A:
undetectable
5eeuH-4bx9A:
7.91
5eeuI-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eeuI-4bx9A:
undetectable
5eeuJ-4bx9A:
undetectable
5eeuI-4bx9A:
7.91
5eeuJ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.09A 5eeuJ-4bx9A:
undetectable
5eeuK-4bx9A:
undetectable
5eeuJ-4bx9A:
7.91
5eeuK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.11A 5eeuA-4bx9A:
undetectable
5eeuK-4bx9A:
undetectable
5eeuA-4bx9A:
7.91
5eeuK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eeuN-4bx9A:
undetectable
5eeuO-4bx9A:
undetectable
5eeuN-4bx9A:
7.91
5eeuO-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eeuO-4bx9A:
undetectable
5eeuP-4bx9A:
undetectable
5eeuO-4bx9A:
7.91
5eeuP-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eeuP-4bx9A:
undetectable
5eeuQ-4bx9A:
undetectable
5eeuP-4bx9A:
7.91
5eeuQ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.11A 5eeuQ-4bx9A:
undetectable
5eeuR-4bx9A:
undetectable
5eeuQ-4bx9A:
7.91
5eeuR-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eeuR-4bx9A:
undetectable
5eeuS-4bx9A:
undetectable
5eeuR-4bx9A:
7.91
5eeuS-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eeuS-4bx9A:
undetectable
5eeuT-4bx9A:
undetectable
5eeuS-4bx9A:
7.91
5eeuT-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eeuT-4bx9A:
undetectable
5eeuU-4bx9A:
undetectable
5eeuT-4bx9A:
7.91
5eeuU-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.10A 5eeuU-4bx9A:
undetectable
5eeuV-4bx9A:
undetectable
5eeuU-4bx9A:
7.91
5eeuV-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eevA-4bx9A:
undetectable
5eevB-4bx9A:
undetectable
5eevA-4bx9A:
7.91
5eevB-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5eevB-4bx9A:
undetectable
5eevC-4bx9A:
undetectable
5eevB-4bx9A:
7.91
5eevC-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5eevC-4bx9A:
undetectable
5eevD-4bx9A:
undetectable
5eevC-4bx9A:
7.91
5eevD-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eevD-4bx9A:
undetectable
5eevE-4bx9A:
undetectable
5eevD-4bx9A:
7.91
5eevE-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eevE-4bx9A:
undetectable
5eevF-4bx9A:
undetectable
5eevE-4bx9A:
7.91
5eevF-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eevF-4bx9A:
undetectable
5eevG-4bx9A:
undetectable
5eevF-4bx9A:
7.91
5eevG-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.08A 5eevG-4bx9A:
undetectable
5eevH-4bx9A:
undetectable
5eevG-4bx9A:
7.91
5eevH-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eevH-4bx9A:
undetectable
5eevI-4bx9A:
undetectable
5eevH-4bx9A:
7.91
5eevI-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eevI-4bx9A:
undetectable
5eevJ-4bx9A:
undetectable
5eevI-4bx9A:
7.91
5eevJ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.09A 5eevJ-4bx9A:
undetectable
5eevK-4bx9A:
undetectable
5eevJ-4bx9A:
7.91
5eevK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.11A 5eevA-4bx9A:
undetectable
5eevK-4bx9A:
undetectable
5eevA-4bx9A:
7.91
5eevK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eevN-4bx9A:
undetectable
5eevO-4bx9A:
undetectable
5eevN-4bx9A:
7.91
5eevO-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eevO-4bx9A:
undetectable
5eevP-4bx9A:
undetectable
5eevO-4bx9A:
7.91
5eevP-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eevP-4bx9A:
undetectable
5eevQ-4bx9A:
undetectable
5eevP-4bx9A:
7.91
5eevQ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eevQ-4bx9A:
undetectable
5eevR-4bx9A:
undetectable
5eevQ-4bx9A:
7.91
5eevR-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eevR-4bx9A:
undetectable
5eevS-4bx9A:
undetectable
5eevR-4bx9A:
7.91
5eevS-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eevS-4bx9A:
undetectable
5eevT-4bx9A:
undetectable
5eevS-4bx9A:
7.91
5eevT-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eevT-4bx9A:
undetectable
5eevU-4bx9A:
undetectable
5eevT-4bx9A:
7.91
5eevU-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.10A 5eevU-4bx9A:
undetectable
5eevV-4bx9A:
undetectable
5eevU-4bx9A:
7.91
5eevV-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eewA-4bx9A:
undetectable
5eewB-4bx9A:
undetectable
5eewA-4bx9A:
7.91
5eewB-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5eewB-4bx9A:
undetectable
5eewC-4bx9A:
undetectable
5eewB-4bx9A:
7.91
5eewC-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5eewC-4bx9A:
undetectable
5eewD-4bx9A:
undetectable
5eewC-4bx9A:
7.91
5eewD-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eewD-4bx9A:
undetectable
5eewE-4bx9A:
undetectable
5eewD-4bx9A:
7.91
5eewE-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eewE-4bx9A:
undetectable
5eewF-4bx9A:
undetectable
5eewE-4bx9A:
7.91
5eewF-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eewF-4bx9A:
undetectable
5eewG-4bx9A:
undetectable
5eewF-4bx9A:
7.91
5eewG-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.08A 5eewG-4bx9A:
undetectable
5eewH-4bx9A:
undetectable
5eewG-4bx9A:
7.91
5eewH-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eewH-4bx9A:
undetectable
5eewI-4bx9A:
undetectable
5eewH-4bx9A:
7.91
5eewI-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eewI-4bx9A:
undetectable
5eewJ-4bx9A:
undetectable
5eewI-4bx9A:
7.91
5eewJ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.09A 5eewJ-4bx9A:
undetectable
5eewK-4bx9A:
undetectable
5eewJ-4bx9A:
7.91
5eewK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eewA-4bx9A:
undetectable
5eewK-4bx9A:
undetectable
5eewA-4bx9A:
7.91
5eewK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eewN-4bx9A:
undetectable
5eewO-4bx9A:
undetectable
5eewN-4bx9A:
7.91
5eewO-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eewO-4bx9A:
undetectable
5eewP-4bx9A:
undetectable
5eewO-4bx9A:
7.91
5eewP-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eewP-4bx9A:
undetectable
5eewQ-4bx9A:
undetectable
5eewP-4bx9A:
7.91
5eewQ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eewQ-4bx9A:
undetectable
5eewR-4bx9A:
undetectable
5eewQ-4bx9A:
7.91
5eewR-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eewR-4bx9A:
undetectable
5eewS-4bx9A:
undetectable
5eewR-4bx9A:
7.91
5eewS-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eewS-4bx9A:
undetectable
5eewT-4bx9A:
undetectable
5eewS-4bx9A:
7.91
5eewT-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eewT-4bx9A:
undetectable
5eewU-4bx9A:
undetectable
5eewT-4bx9A:
7.91
5eewU-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.11A 5eewU-4bx9A:
undetectable
5eewV-4bx9A:
undetectable
5eewU-4bx9A:
7.91
5eewV-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eexA-4bx9A:
undetectable
5eexB-4bx9A:
undetectable
5eexA-4bx9A:
7.91
5eexB-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5eexB-4bx9A:
undetectable
5eexC-4bx9A:
undetectable
5eexB-4bx9A:
7.91
5eexC-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5eexC-4bx9A:
undetectable
5eexD-4bx9A:
undetectable
5eexC-4bx9A:
7.91
5eexD-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eexD-4bx9A:
undetectable
5eexE-4bx9A:
undetectable
5eexD-4bx9A:
7.91
5eexE-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eexE-4bx9A:
undetectable
5eexF-4bx9A:
undetectable
5eexE-4bx9A:
7.91
5eexF-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eexF-4bx9A:
undetectable
5eexG-4bx9A:
undetectable
5eexF-4bx9A:
7.91
5eexG-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.08A 5eexG-4bx9A:
undetectable
5eexH-4bx9A:
undetectable
5eexG-4bx9A:
7.91
5eexH-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eexH-4bx9A:
undetectable
5eexI-4bx9A:
undetectable
5eexH-4bx9A:
7.91
5eexI-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eexI-4bx9A:
undetectable
5eexJ-4bx9A:
undetectable
5eexI-4bx9A:
7.91
5eexJ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eexJ-4bx9A:
undetectable
5eexK-4bx9A:
undetectable
5eexJ-4bx9A:
7.91
5eexK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eexA-4bx9A:
undetectable
5eexK-4bx9A:
undetectable
5eexA-4bx9A:
7.91
5eexK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eexN-4bx9A:
undetectable
5eexO-4bx9A:
undetectable
5eexN-4bx9A:
7.91
5eexO-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eexO-4bx9A:
undetectable
5eexP-4bx9A:
undetectable
5eexO-4bx9A:
7.91
5eexP-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eexP-4bx9A:
undetectable
5eexQ-4bx9A:
undetectable
5eexP-4bx9A:
7.91
5eexQ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eexQ-4bx9A:
undetectable
5eexR-4bx9A:
undetectable
5eexQ-4bx9A:
7.91
5eexR-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eexR-4bx9A:
undetectable
5eexS-4bx9A:
undetectable
5eexR-4bx9A:
7.91
5eexS-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eexS-4bx9A:
undetectable
5eexT-4bx9A:
undetectable
5eexS-4bx9A:
7.91
5eexT-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eexT-4bx9A:
undetectable
5eexU-4bx9A:
undetectable
5eexT-4bx9A:
7.91
5eexU-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.10A 5eexU-4bx9A:
undetectable
5eexV-4bx9A:
undetectable
5eexU-4bx9A:
7.91
5eexV-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eeyA-4bx9A:
undetectable
5eeyB-4bx9A:
undetectable
5eeyA-4bx9A:
7.91
5eeyB-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5eeyB-4bx9A:
undetectable
5eeyC-4bx9A:
undetectable
5eeyB-4bx9A:
7.91
5eeyC-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5eeyC-4bx9A:
undetectable
5eeyD-4bx9A:
undetectable
5eeyC-4bx9A:
7.91
5eeyD-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eeyD-4bx9A:
undetectable
5eeyE-4bx9A:
undetectable
5eeyD-4bx9A:
7.91
5eeyE-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eeyE-4bx9A:
undetectable
5eeyF-4bx9A:
undetectable
5eeyE-4bx9A:
7.91
5eeyF-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eeyF-4bx9A:
undetectable
5eeyG-4bx9A:
undetectable
5eeyF-4bx9A:
7.91
5eeyG-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.08A 5eeyG-4bx9A:
undetectable
5eeyH-4bx9A:
undetectable
5eeyG-4bx9A:
7.91
5eeyH-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eeyH-4bx9A:
undetectable
5eeyI-4bx9A:
undetectable
5eeyH-4bx9A:
7.91
5eeyI-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eeyI-4bx9A:
undetectable
5eeyJ-4bx9A:
undetectable
5eeyI-4bx9A:
7.91
5eeyJ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eeyJ-4bx9A:
undetectable
5eeyK-4bx9A:
undetectable
5eeyJ-4bx9A:
7.91
5eeyK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eeyA-4bx9A:
undetectable
5eeyK-4bx9A:
undetectable
5eeyA-4bx9A:
7.91
5eeyK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eeyN-4bx9A:
undetectable
5eeyO-4bx9A:
undetectable
5eeyN-4bx9A:
7.91
5eeyO-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eeyO-4bx9A:
undetectable
5eeyP-4bx9A:
undetectable
5eeyO-4bx9A:
7.91
5eeyP-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eeyP-4bx9A:
undetectable
5eeyQ-4bx9A:
undetectable
5eeyP-4bx9A:
7.91
5eeyQ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eeyQ-4bx9A:
undetectable
5eeyR-4bx9A:
undetectable
5eeyQ-4bx9A:
7.91
5eeyR-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eeyR-4bx9A:
undetectable
5eeyS-4bx9A:
undetectable
5eeyR-4bx9A:
7.91
5eeyS-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eeyS-4bx9A:
undetectable
5eeyT-4bx9A:
undetectable
5eeyS-4bx9A:
7.91
5eeyT-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eeyT-4bx9A:
undetectable
5eeyU-4bx9A:
undetectable
5eeyT-4bx9A:
7.91
5eeyU-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.11A 5eeyU-4bx9A:
undetectable
5eeyV-4bx9A:
undetectable
5eeyU-4bx9A:
7.91
5eeyV-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eezA-4bx9A:
undetectable
5eezB-4bx9A:
undetectable
5eezA-4bx9A:
7.91
5eezB-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5eezB-4bx9A:
undetectable
5eezC-4bx9A:
undetectable
5eezB-4bx9A:
7.91
5eezC-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5eezC-4bx9A:
undetectable
5eezD-4bx9A:
undetectable
5eezC-4bx9A:
7.91
5eezD-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eezD-4bx9A:
undetectable
5eezE-4bx9A:
undetectable
5eezD-4bx9A:
7.91
5eezE-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eezE-4bx9A:
undetectable
5eezF-4bx9A:
undetectable
5eezE-4bx9A:
7.91
5eezF-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eezF-4bx9A:
undetectable
5eezG-4bx9A:
undetectable
5eezF-4bx9A:
7.91
5eezG-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.08A 5eezG-4bx9A:
undetectable
5eezH-4bx9A:
undetectable
5eezG-4bx9A:
7.91
5eezH-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eezH-4bx9A:
undetectable
5eezI-4bx9A:
undetectable
5eezH-4bx9A:
7.91
5eezI-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5eezI-4bx9A:
undetectable
5eezJ-4bx9A:
undetectable
5eezI-4bx9A:
7.91
5eezJ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5eezJ-4bx9A:
undetectable
5eezK-4bx9A:
undetectable
5eezJ-4bx9A:
7.91
5eezK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eezA-4bx9A:
undetectable
5eezK-4bx9A:
undetectable
5eezA-4bx9A:
7.91
5eezK-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eezN-4bx9A:
undetectable
5eezO-4bx9A:
undetectable
5eezN-4bx9A:
7.91
5eezO-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eezO-4bx9A:
undetectable
5eezP-4bx9A:
undetectable
5eezO-4bx9A:
7.91
5eezP-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eezP-4bx9A:
undetectable
5eezQ-4bx9A:
undetectable
5eezP-4bx9A:
7.91
5eezQ-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eezQ-4bx9A:
undetectable
5eezR-4bx9A:
undetectable
5eezQ-4bx9A:
7.91
5eezR-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5eezR-4bx9A:
undetectable
5eezS-4bx9A:
undetectable
5eezR-4bx9A:
7.91
5eezS-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.14A 5eezS-4bx9A:
undetectable
5eezT-4bx9A:
undetectable
5eezS-4bx9A:
7.91
5eezT-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5eezT-4bx9A:
undetectable
5eezU-4bx9A:
undetectable
5eezT-4bx9A:
7.91
5eezU-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.11A 5eezU-4bx9A:
undetectable
5eezV-4bx9A:
undetectable
5eezU-4bx9A:
7.91
5eezV-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef0A-4bx9A:
undetectable
5ef0B-4bx9A:
undetectable
5ef0A-4bx9A:
7.91
5ef0B-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5ef0B-4bx9A:
undetectable
5ef0C-4bx9A:
undetectable
5ef0B-4bx9A:
7.91
5ef0C-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5ef0C-4bx9A:
undetectable
5ef0D-4bx9A:
undetectable
5ef0C-4bx9A:
7.91
5ef0D-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef0D-4bx9A:
undetectable
5ef0E-4bx9A:
undetectable
5ef0D-4bx9A:
7.91
5ef0E-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef0E-4bx9A:
undetectable
5ef0F-4bx9A:
undetectable
5ef0E-4bx9A:
7.91
5ef0F-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef0F-4bx9A:
undetectable
5ef0G-4bx9A:
undetectable
5ef0F-4bx9A:
7.91
5ef0G-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.09A 5ef0G-4bx9A:
undetectable
5ef0H-4bx9A:
undetectable
5ef0G-4bx9A:
7.91
5ef0H-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef0H-4bx9A:
undetectable
5ef0I-4bx9A:
undetectable
5ef0H-4bx9A:
7.91
5ef0I-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef0I-4bx9A:
undetectable
5ef0J-4bx9A:
undetectable
5ef0I-4bx9A:
7.91
5ef0J-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5ef0J-4bx9A:
undetectable
5ef0K-4bx9A:
undetectable
5ef0J-4bx9A:
7.91
5ef0K-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5ef0A-4bx9A:
undetectable
5ef0K-4bx9A:
undetectable
5ef0A-4bx9A:
7.91
5ef0K-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef0N-4bx9A:
undetectable
5ef0O-4bx9A:
undetectable
5ef0N-4bx9A:
7.91
5ef0O-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef0O-4bx9A:
undetectable
5ef0P-4bx9A:
undetectable
5ef0O-4bx9A:
7.91
5ef0P-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef0P-4bx9A:
undetectable
5ef0Q-4bx9A:
undetectable
5ef0P-4bx9A:
7.91
5ef0Q-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5ef0Q-4bx9A:
undetectable
5ef0R-4bx9A:
undetectable
5ef0Q-4bx9A:
7.91
5ef0R-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef0R-4bx9A:
undetectable
5ef0S-4bx9A:
undetectable
5ef0R-4bx9A:
7.91
5ef0S-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef0S-4bx9A:
undetectable
5ef0T-4bx9A:
undetectable
5ef0S-4bx9A:
7.91
5ef0T-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5ef0T-4bx9A:
undetectable
5ef0U-4bx9A:
undetectable
5ef0T-4bx9A:
7.91
5ef0U-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.11A 5ef0U-4bx9A:
undetectable
5ef0V-4bx9A:
undetectable
5ef0U-4bx9A:
7.91
5ef0V-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef1A-4bx9A:
undetectable
5ef1B-4bx9A:
undetectable
5ef1A-4bx9A:
7.91
5ef1B-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.13A 5ef1B-4bx9A:
undetectable
5ef1C-4bx9A:
undetectable
5ef1B-4bx9A:
7.91
5ef1C-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5ef1C-4bx9A:
undetectable
5ef1D-4bx9A:
undetectable
5ef1C-4bx9A:
7.91
5ef1D-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef1D-4bx9A:
undetectable
5ef1E-4bx9A:
undetectable
5ef1D-4bx9A:
7.91
5ef1E-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef1E-4bx9A:
undetectable
5ef1F-4bx9A:
undetectable
5ef1E-4bx9A:
7.91
5ef1F-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef1F-4bx9A:
undetectable
5ef1G-4bx9A:
undetectable
5ef1F-4bx9A:
7.91
5ef1G-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.09A 5ef1G-4bx9A:
undetectable
5ef1H-4bx9A:
undetectable
5ef1G-4bx9A:
7.91
5ef1H-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef1H-4bx9A:
undetectable
5ef1I-4bx9A:
undetectable
5ef1H-4bx9A:
7.91
5ef1I-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef1I-4bx9A:
undetectable
5ef1J-4bx9A:
undetectable
5ef1I-4bx9A:
7.91
5ef1J-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5ef1J-4bx9A:
undetectable
5ef1K-4bx9A:
undetectable
5ef1J-4bx9A:
7.91
5ef1K-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5ef1A-4bx9A:
undetectable
5ef1K-4bx9A:
undetectable
5ef1A-4bx9A:
7.91
5ef1K-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef1N-4bx9A:
undetectable
5ef1O-4bx9A:
undetectable
5ef1N-4bx9A:
7.91
5ef1O-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef1O-4bx9A:
undetectable
5ef1P-4bx9A:
undetectable
5ef1O-4bx9A:
7.91
5ef1P-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef1P-4bx9A:
undetectable
5ef1Q-4bx9A:
undetectable
5ef1P-4bx9A:
7.91
5ef1Q-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5ef1Q-4bx9A:
undetectable
5ef1R-4bx9A:
undetectable
5ef1Q-4bx9A:
7.91
5ef1R-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef1R-4bx9A:
undetectable
5ef1S-4bx9A:
undetectable
5ef1R-4bx9A:
7.91
5ef1S-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.14A 5ef1S-4bx9A:
undetectable
5ef1T-4bx9A:
undetectable
5ef1S-4bx9A:
7.91
5ef1T-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef1T-4bx9A:
undetectable
5ef1U-4bx9A:
undetectable
5ef1T-4bx9A:
7.91
5ef1U-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.11A 5ef1U-4bx9A:
undetectable
5ef1V-4bx9A:
undetectable
5ef1U-4bx9A:
7.91
5ef1V-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef2A-4bx9A:
undetectable
5ef2B-4bx9A:
undetectable
5ef2A-4bx9A:
7.91
5ef2B-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.13A 5ef2B-4bx9A:
undetectable
5ef2C-4bx9A:
undetectable
5ef2B-4bx9A:
7.91
5ef2C-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5ef2C-4bx9A:
undetectable
5ef2D-4bx9A:
undetectable
5ef2C-4bx9A:
7.91
5ef2D-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef2D-4bx9A:
undetectable
5ef2E-4bx9A:
undetectable
5ef2D-4bx9A:
7.91
5ef2E-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef2E-4bx9A:
undetectable
5ef2F-4bx9A:
undetectable
5ef2E-4bx9A:
7.91
5ef2F-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef2F-4bx9A:
undetectable
5ef2G-4bx9A:
undetectable
5ef2F-4bx9A:
7.91
5ef2G-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.09A 5ef2G-4bx9A:
undetectable
5ef2H-4bx9A:
undetectable
5ef2G-4bx9A:
7.91
5ef2H-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef2H-4bx9A:
undetectable
5ef2I-4bx9A:
undetectable
5ef2H-4bx9A:
7.91
5ef2I-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef2I-4bx9A:
undetectable
5ef2J-4bx9A:
undetectable
5ef2I-4bx9A:
7.91
5ef2J-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5ef2J-4bx9A:
undetectable
5ef2K-4bx9A:
undetectable
5ef2J-4bx9A:
7.91
5ef2K-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5ef2A-4bx9A:
undetectable
5ef2K-4bx9A:
undetectable
5ef2A-4bx9A:
7.91
5ef2K-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef2N-4bx9A:
undetectable
5ef2O-4bx9A:
undetectable
5ef2N-4bx9A:
7.91
5ef2O-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef2O-4bx9A:
undetectable
5ef2P-4bx9A:
undetectable
5ef2O-4bx9A:
7.91
5ef2P-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef2P-4bx9A:
undetectable
5ef2Q-4bx9A:
undetectable
5ef2P-4bx9A:
7.91
5ef2Q-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5ef2Q-4bx9A:
undetectable
5ef2R-4bx9A:
undetectable
5ef2Q-4bx9A:
7.91
5ef2R-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef2R-4bx9A:
undetectable
5ef2S-4bx9A:
undetectable
5ef2R-4bx9A:
7.91
5ef2S-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.14A 5ef2S-4bx9A:
undetectable
5ef2T-4bx9A:
undetectable
5ef2S-4bx9A:
7.91
5ef2T-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef2T-4bx9A:
undetectable
5ef2U-4bx9A:
undetectable
5ef2T-4bx9A:
7.91
5ef2U-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.11A 5ef2U-4bx9A:
undetectable
5ef2V-4bx9A:
undetectable
5ef2U-4bx9A:
7.91
5ef2V-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef3A-4bx9A:
undetectable
5ef3B-4bx9A:
undetectable
5ef3A-4bx9A:
7.91
5ef3B-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.13A 5ef3B-4bx9A:
undetectable
5ef3C-4bx9A:
undetectable
5ef3B-4bx9A:
7.91
5ef3C-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5ef3C-4bx9A:
undetectable
5ef3D-4bx9A:
undetectable
5ef3C-4bx9A:
7.91
5ef3D-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef3D-4bx9A:
undetectable
5ef3E-4bx9A:
undetectable
5ef3D-4bx9A:
7.91
5ef3E-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5ef3E-4bx9A:
undetectable
5ef3F-4bx9A:
undetectable
5ef3E-4bx9A:
7.91
5ef3F-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef3F-4bx9A:
undetectable
5ef3G-4bx9A:
undetectable
5ef3F-4bx9A:
7.91
5ef3G-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.09A 5ef3G-4bx9A:
undetectable
5ef3H-4bx9A:
undetectable
5ef3G-4bx9A:
7.91
5ef3H-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.11A 5ef3H-4bx9A:
undetectable
5ef3I-4bx9A:
undetectable
5ef3H-4bx9A:
7.91
5ef3I-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 11 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.12A 5ef3I-4bx9A:
undetectable
5ef3J-4bx9A:
undetectable
5ef3I-4bx9A:
7.91
5ef3J-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 SER A 504
ALA A 500
THR A 572
THR A 545
ILE A 547
None
1.10A 5ef3J-4bx9A:
undetectable
5ef3K-4bx9A:
undetectable
5ef3J-4bx9A:
7.91
5ef3K-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5ef3A-4bx9A:
undetectable
5ef3K-4bx9A:
undetectable
5ef3A-4bx9A:
7.91
5ef3K-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef3N-4bx9A:
undetectable
5ef3O-4bx9A:
undetectable
5ef3N-4bx9A:
7.91
5ef3O-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef3O-4bx9A:
undetectable
5ef3P-4bx9A:
undetectable
5ef3O-4bx9A:
7.91
5ef3P-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef3P-4bx9A:
undetectable
5ef3Q-4bx9A:
undetectable
5ef3P-4bx9A:
7.91
5ef3Q-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 9 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.12A 5ef3Q-4bx9A:
undetectable
5ef3R-4bx9A:
undetectable
5ef3Q-4bx9A:
7.91
5ef3R-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.14A 5ef3R-4bx9A:
undetectable
5ef3S-4bx9A:
undetectable
5ef3R-4bx9A:
7.91
5ef3S-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.14A 5ef3S-4bx9A:
undetectable
5ef3T-4bx9A:
undetectable
5ef3S-4bx9A:
7.91
5ef3T-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.13A 5ef3T-4bx9A:
undetectable
5ef3U-4bx9A:
undetectable
5ef3T-4bx9A:
7.91
5ef3U-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 10 ALA A 500
THR A 572
THR A 545
ILE A 547
SER A 504
None
1.11A 5ef3U-4bx9A:
undetectable
5ef3V-4bx9A:
undetectable
5ef3U-4bx9A:
7.91
5ef3V-4bx9A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 ILE A 111
LEU A 125
GLU A 139
PHE A 113
HIS A 174
None
1.31A 5k7uA-4bx9A:
undetectable
5k7uA-4bx9A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 ILE A  80
VAL A  83
PHE A 113
VAL A 114
ILE A 135
None
1.09A 5n0sA-4bx9A:
undetectable
5n0sA-4bx9A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 ILE A  80
VAL A  83
PHE A 113
VAL A 114
ILE A 135
None
1.09A 5n0sB-4bx9A:
undetectable
5n0sB-4bx9A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
5 / 12 SER A 259
ILE A 250
HIS A   4
LEU A   5
LEU A  48
None
1.46A 5ycpA-4bx9A:
undetectable
5ycpA-4bx9A:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYN_A_HSMA901_0
(EBONY)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 4 GLU A  22
VAL A  19
LEU A  15
THR A 181
None
None
None
FMT  A1596 ( 4.0A)
1.37A 6dynA-4bx9A:
undetectable
6dynA-4bx9A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 5 GLU A  22
VAL A  19
LEU A  15
THR A 181
None
None
None
FMT  A1596 ( 4.0A)
1.38A 6dyoA-4bx9A:
undetectable
6dyoA-4bx9A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo
sapiens)
4 / 6 VAL A 406
LEU A 447
LEU A 444
HIS A 440
None
0.99A 6e43D-4bx9A:
undetectable
6e43D-4bx9A:
22.42