SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bxs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 10 TYR V 798
PRO V 857
ARG V 796
ILE V 967
PRO V 958
None
1.38A 13gsA-4bxsV:
undetectable
13gsA-4bxsV:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 HIS V 884
ILE V 959
LEU V 855
GLY V 856
VAL V 980
None
1.16A 1axwA-4bxsV:
undetectable
1axwA-4bxsV:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 8 ASP V 612
HIS V 884
HIS V 882
HIS V 598
None
0.98A 1ei6D-4bxsV:
undetectable
1ei6D-4bxsV:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.40A 1l7fA-4bxsV:
undetectable
1l7fA-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 ARG V 926
ILE V 961
TRP V 939
None
1.16A 1m8eB-4bxsV:
undetectable
1m8eB-4bxsV:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLY V 494
VAL V 520
LEU V 392
ILE V 488
LEU V 492
None
0.97A 1mx1D-4bxsV:
undetectable
1mx1D-4bxsV:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 ARG V 926
ILE V 961
TRP V 939
None
1.00A 1nodB-4bxsV:
undetectable
1nodB-4bxsV:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 LEU V1329
GLY V1282
GLY V1278
ILE V1289
THR V1315
None
1.08A 1p91B-4bxsV:
undetectable
1p91B-4bxsV:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 ARG V 926
ILE V 961
TRP V 939
None
0.95A 1qomA-4bxsV:
undetectable
1qomA-4bxsV:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 HIS V 884
ILE V 959
LEU V 855
GLY V 856
VAL V 980
None
1.11A 1tlsB-4bxsV:
undetectable
1tlsB-4bxsV:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLY V 957
ILE V 800
ALA V 802
ILE V 951
SER V 943
None
1.07A 1ve3B-4bxsV:
undetectable
1ve3B-4bxsV:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 LEU V 614
PHE V 604
ARG V 649
None
0.83A 1xdkF-4bxsV:
undetectable
1xdkF-4bxsV:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 5 TRP V1414
PRO V1411
LEU V1420
GLY V1346
None
1.42A 1ya4C-4bxsV:
undetectable
1ya4C-4bxsV:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 11 VAL V1202
ILE V1180
GLY V1182
ILE V1263
LEU V1250
None
0.97A 1z11A-4bxsV:
undetectable
1z11A-4bxsV:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 11 VAL V1202
ILE V1180
GLY V1182
ILE V1263
LEU V1250
None
0.96A 1z11B-4bxsV:
undetectable
1z11B-4bxsV:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 10 VAL V1202
ILE V1180
GLY V1182
ILE V1263
LEU V1250
None
0.96A 1z11C-4bxsV:
undetectable
1z11C-4bxsV:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 10 VAL V1202
ILE V1180
GLY V1182
ILE V1263
LEU V1250
None
1.00A 1z11D-4bxsV:
undetectable
1z11D-4bxsV:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 4 SER V 147
ASP V 113
ARG V 110
ASP V 107
None
CA  V2430 (-2.7A)
None
None
1.30A 2bm9C-4bxsV:
undetectable
2bm9C-4bxsV:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 LYS V1338
ASP V1114
ASP V1033
None
1.05A 2br4A-4bxsV:
undetectable
2br4A-4bxsV:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 6 LEU V 163
TYR V 143
ILE V 165
GLY V1056
None
0.91A 2du8A-4bxsV:
undetectable
2du8A-4bxsV:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 6 LEU V 163
TYR V 143
ILE V 165
GLY V1056
None
0.92A 2du8B-4bxsV:
undetectable
2du8B-4bxsV:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 7 TYR V 888
GLY V 894
TYR V 942
ASP V 909
None
None
None
CA  V2431 (-3.3A)
0.96A 2g72B-4bxsV:
undetectable
2g72B-4bxsV:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLY V1278
ILE V1407
ILE V1339
ILE V1343
ILE V1331
None
0.96A 2hs1A-4bxsV:
undetectable
2hs1A-4bxsV:
5.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLY V1278
ILE V1407
ILE V1339
ILE V1343
ILE V1331
None
0.87A 2hs1B-4bxsV:
undetectable
2hs1B-4bxsV:
5.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 6 GLY V1386
PHE V1359
PRO V1411
THR V1413
None
1.21A 2m2oB-4bxsV:
undetectable
2m2oB-4bxsV:
2.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 ARG V 926
ILE V 961
TRP V 939
None
0.96A 2nodB-4bxsV:
undetectable
2nodB-4bxsV:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 8 HIS V 225
SER V 274
SER V 424
ASP V 270
None
1.18A 2obvA-4bxsV:
undetectable
2obvA-4bxsV:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA504_0
(CHORISMATE SYNTHASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 5 SER V 283
HIS V 288
LEU V 261
SER V 241
None
1.36A 2qhfA-4bxsV:
undetectable
2qhfA-4bxsV:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 HIS V 479
MET V 619
MET V 484
None
1.34A 2vj1A-4bxsV:
undetectable
2vj1A-4bxsV:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 LEU V1149
GLU V1236
ILE V1183
None
0.57A 3czhA-4bxsV:
undetectable
3czhA-4bxsV:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 LEU V1040
ASN V1053
PRO V  87
VAL V1052
PRO V1086
None
1.06A 3dcjA-4bxsV:
undetectable
3dcjB-4bxsV:
undetectable
3dcjA-4bxsV:
9.92
3dcjB-4bxsV:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 ARG V 926
ILE V 961
TRP V 939
None
1.15A 3e68A-4bxsV:
undetectable
3e68A-4bxsV:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 ARG V 926
ILE V 961
TRP V 939
None
1.13A 3e6tB-4bxsV:
undetectable
3e6tB-4bxsV:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 ARG V 926
ILE V 961
TRP V 939
None
1.10A 3e7iB-4bxsV:
undetectable
3e7iB-4bxsV:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.24A 3k37A-4bxsV:
undetectable
3k37A-4bxsV:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.28A 3k39A-4bxsV:
undetectable
3k39A-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.27A 3k39C-4bxsV:
undetectable
3k39C-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.27A 3k39D-4bxsV:
undetectable
3k39D-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.27A 3k39E-4bxsV:
undetectable
3k39E-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.26A 3k39F-4bxsV:
undetectable
3k39F-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.27A 3k39G-4bxsV:
undetectable
3k39G-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.25A 3k39H-4bxsV:
undetectable
3k39H-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.27A 3k39I-4bxsV:
undetectable
3k39I-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.27A 3k39J-4bxsV:
undetectable
3k39J-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.28A 3k39K-4bxsV:
undetectable
3k39K-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.26A 3k39L-4bxsV:
undetectable
3k39L-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.29A 3k39M-4bxsV:
undetectable
3k39M-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.25A 3k39N-4bxsV:
undetectable
3k39N-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_P_BCZP1001_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.27A 3k39P-4bxsV:
undetectable
3k39P-4bxsV:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 LYS V 366
GLY V 589
ALA V 522
ASP V 592
ALA V 286
None
None
None
MAN  V1501 (-3.8A)
None
1.23A 3nmuA-4bxsV:
undetectable
3nmuF-4bxsV:
undetectable
3nmuA-4bxsV:
14.50
3nmuF-4bxsV:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 ARG V 926
ILE V 961
TRP V 939
None
0.99A 3nw2A-4bxsV:
undetectable
3nw2A-4bxsV:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 ARG V 926
ILE V 961
TRP V 939
None
0.95A 3nw2B-4bxsV:
undetectable
3nw2B-4bxsV:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 11 GLY V 118
SER V 120
PHE V  75
ALA V   9
ALA V  10
None
1.13A 3sufC-4bxsV:
undetectable
3sufC-4bxsV:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 6 TYR V 888
GLY V 601
HIS V 598
THR V 603
None
1.00A 3tj7A-4bxsV:
undetectable
3tj7B-4bxsV:
undetectable
3tj7A-4bxsV:
8.73
3tj7B-4bxsV:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 6 TYR V 888
GLY V 601
HIS V 598
THR V 603
None
0.98A 3tj7C-4bxsV:
undetectable
3tj7D-4bxsV:
undetectable
3tj7C-4bxsV:
8.73
3tj7D-4bxsV:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 6 HIS V 598
THR V 603
TYR V 888
GLY V 601
None
1.04A 3tj7C-4bxsV:
undetectable
3tj7D-4bxsV:
undetectable
3tj7C-4bxsV:
8.73
3tj7D-4bxsV:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 5 VAL V 368
GLY V 491
TYR V 416
ASP V 487
None
1.25A 3w9tA-4bxsV:
undetectable
3w9tA-4bxsV:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 5 VAL V 368
GLY V 491
TYR V 416
ASP V 487
None
1.24A 3w9tD-4bxsV:
undetectable
3w9tD-4bxsV:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 5 VAL V 368
GLY V 491
TYR V 416
ASP V 487
None
1.24A 3w9tE-4bxsV:
undetectable
3w9tE-4bxsV:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 5 VAL V 368
GLY V 491
TYR V 416
ASP V 487
None
1.25A 3w9tF-4bxsV:
undetectable
3w9tF-4bxsV:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 8 TYR V 941
TYR V 798
TRP V 921
ARG V 796
None
1.49A 3wipC-4bxsV:
undetectable
3wipD-4bxsV:
undetectable
3wipC-4bxsV:
10.98
3wipD-4bxsV:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
3 / 3 ARG V 895
TRP V 634
GLY V 601
None
0.93A 4e7cA-4bxsV:
undetectable
4e7cA-4bxsV:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 7 ASP V 487
ASN V 410
GLU V 449
GLU V 331
None
1.02A 4fevB-4bxsV:
undetectable
4fevB-4bxsV:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 LEU V 852
PHE V 982
VAL V 980
PHE V 986
GLY V1105
None
1.35A 4hvcB-4bxsV:
undetectable
4hvcB-4bxsV:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 8 HIS V 225
SER V 274
SER V 424
ASP V 270
None
1.18A 4kttA-4bxsV:
undetectable
4kttA-4bxsV:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 8 HIS V 225
SER V 274
SER V 424
ASP V 270
None
1.12A 4kttC-4bxsV:
undetectable
4kttC-4bxsV:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 ALA V  10
ILE V 231
TYR V 145
LEU V  63
LEU V 163
None
1.20A 4l9qB-4bxsV:
undetectable
4l9qB-4bxsV:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_0
(NEURAMINIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 978
LEU V 960
ARG V 860
GLU V1034
ARG V 977
None
1.39A 4mwvA-4bxsV:
undetectable
4mwvA-4bxsV:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 8 HIS V 225
SER V 274
SER V 424
ASP V 270
None
1.21A 4ndnA-4bxsV:
undetectable
4ndnA-4bxsV:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 LEU V 981
LEU V1040
VAL V1036
MET V1084
ILE V 858
None
1.19A 4oktA-4bxsV:
undetectable
4oktA-4bxsV:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 8 HIS V 225
SER V 274
SER V 424
ASP V 270
None
1.19A 5a1iA-4bxsV:
undetectable
5a1iA-4bxsV:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 4 ALA V 398
PRO V 495
LEU V 585
HIS V 584
None
1.47A 5eskA-4bxsV:
undetectable
5eskA-4bxsV:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 4 ALA V 940
PRO V 947
LEU V 635
HIS V 598
None
1.13A 5eskA-4bxsV:
undetectable
5eskA-4bxsV:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 5 HIS V1050
VAL V1071
GLY V 264
ALA V 265
None
1.05A 5hwaA-4bxsV:
undetectable
5hwaA-4bxsV:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 GLU V 893
LEU V 599
ASP V 654
LEU V 631
GLY V 632
CA  V2431 ( 4.6A)
None
None
None
None
0.98A 5j7wD-4bxsV:
undetectable
5j7wD-4bxsV:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 8 GLN V 247
ALA V 432
HIS V 421
HIS V 243
None
1.13A 5km8A-4bxsV:
undetectable
5km8B-4bxsV:
undetectable
5km8A-4bxsV:
6.93
5km8B-4bxsV:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 10 ILE V1339
ILE V1407
GLU V1288
ASP V1332
ILE V1284
None
1.20A 5lg3F-4bxsV:
undetectable
5lg3F-4bxsV:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 10 ILE V1339
ILE V1407
GLU V1288
ASP V1332
ILE V1284
None
1.23A 5lg3G-4bxsV:
undetectable
5lg3G-4bxsV:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 10 ILE V1339
ILE V1407
GLU V1288
ASP V1332
ILE V1284
None
1.21A 5lg3H-4bxsV:
undetectable
5lg3H-4bxsV:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 12 ILE V1339
ILE V1407
GLU V1288
ASP V1332
ILE V1284
None
1.21A 5lg3J-4bxsV:
undetectable
5lg3J-4bxsV:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
6 / 9 LEU V1265
PRO V1120
ILE V1183
GLY V1182
LEU V1123
LEU V1149
None
1.36A 5o96A-4bxsV:
undetectable
5o96B-4bxsV:
undetectable
5o96A-4bxsV:
11.11
5o96B-4bxsV:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 5 TYR V 145
TYR V 146
GLY V 161
GLY V  60
None
1.10A 5x7pA-4bxsV:
undetectable
5x7pA-4bxsV:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 7 THR V 463
ASP V 464
LEU V 461
THR V 459
None
0.78A 5zsfA-4bxsV:
undetectable
5zsfB-4bxsV:
undetectable
5zsfA-4bxsV:
4.77
5zsfB-4bxsV:
4.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 10 LEU V 297
LEU V 249
ASP V 270
ILE V 299
SER V 272
None
1.43A 6dlzB-4bxsV:
undetectable
6dlzC-4bxsV:
undetectable
6dlzB-4bxsV:
4.95
6dlzC-4bxsV:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 11 ILE V 299
SER V 272
LEU V 297
LEU V 249
ASP V 270
None
1.43A 6dlzA-4bxsV:
undetectable
6dlzD-4bxsV:
undetectable
6dlzA-4bxsV:
4.95
6dlzD-4bxsV:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 10 LEU V 297
LEU V 249
ASP V 270
ILE V 299
SER V 272
None
1.43A 6dm1B-4bxsV:
undetectable
6dm1C-4bxsV:
undetectable
6dm1B-4bxsV:
4.95
6dm1C-4bxsV:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 11 ILE V 299
SER V 272
LEU V 297
LEU V 249
ASP V 270
None
1.42A 6dm1A-4bxsV:
undetectable
6dm1D-4bxsV:
undetectable
6dm1A-4bxsV:
4.95
6dm1D-4bxsV:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 10 LEU V 297
LEU V 249
ASP V 270
ILE V 299
SER V 272
None
1.45A 6dm2B-4bxsV:
undetectable
6dm2C-4bxsV:
undetectable
6dm2B-4bxsV:
4.95
6dm2C-4bxsV:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 10 ILE V 299
SER V 272
LEU V 297
LEU V 249
ASP V 270
None
1.45A 6dm2A-4bxsV:
undetectable
6dm2D-4bxsV:
undetectable
6dm2A-4bxsV:
4.95
6dm2D-4bxsV:
4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 8 HIS V 225
SER V 274
SER V 424
ASP V 270
None
1.18A 6fbnB-4bxsV:
undetectable
6fbnB-4bxsV:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 8 HIS V 225
SER V 274
SER V 424
ASP V 270
None
1.15A 6fboA-4bxsV:
undetectable
6fboA-4bxsV:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 8 HIS V 225
SER V 274
SER V 424
ASP V 270
None
1.17A 6fcbA-4bxsV:
undetectable
6fcbA-4bxsV:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
4 / 8 HIS V 225
SER V 274
SER V 424
ASP V 270
None
1.18A 6fcdA-4bxsV:
undetectable
6fcdA-4bxsV:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_B_TRPB502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis)
5 / 10 TYR V 941
ALA V 940
LEU V1041
LEU V 855
VAL V 980
None
1.25A 6g2pB-4bxsV:
undetectable
6g2pB-4bxsV:
16.53