SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bxv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	4bxv	PSEUDOAZURIN (Paracoccus pantotrophus)	4 / 5	CYH A 78 PRO A 80 HIS A 81 MET A 86	CU A1124 (-2.6A) None CU A1124 (-4.2A) CU A1124 (-2.8A)	0.95A	1oe2A-4bxvA: 5.7	1oe2A-4bxvA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	4bxv	PSEUDOAZURIN (Paracoccus pantotrophus)	4 / 5	HIS A 40 CYH A 78 PRO A 80 MET A 86	CU A1124 (-3.5A) CU A1124 (-2.6A) None CU A1124 (-2.8A)	0.89A	1oe2A-4bxvA: 5.7	1oe2A-4bxvA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQD_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	4bxv	PSEUDOAZURIN (Paracoccus pantotrophus)	4 / 4	HIS A 40 CYH A 78 HIS A 81 MET A 86	CU A1124 (-3.5A) CU A1124 (-2.6A) CU A1124 (-4.2A) CU A1124 (-2.8A)	0.57A	2fqdA-4bxvA: undetectable	2fqdA-4bxvA: 10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQE_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	4bxv	PSEUDOAZURIN (Paracoccus pantotrophus)	4 / 4	HIS A 40 CYH A 78 HIS A 81 MET A 86	CU A1124 (-3.5A) CU A1124 (-2.6A) CU A1124 (-4.2A) CU A1124 (-2.8A)	0.67A	2fqeA-4bxvA: undetectable	2fqeA-4bxvA: 10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQG_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	4bxv	PSEUDOAZURIN (Paracoccus pantotrophus)	4 / 4	HIS A 40 CYH A 78 HIS A 81 MET A 86	CU A1124 (-3.5A) CU A1124 (-2.6A) CU A1124 (-4.2A) CU A1124 (-2.8A)	0.68A	2fqgA-4bxvA: undetectable	2fqgA-4bxvA: 10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	4bxv	PSEUDOAZURIN (Paracoccus pantotrophus)	4 / 5	CYH A 78 PRO A 80 HIS A 81 MET A 86	CU A1124 (-2.6A) None CU A1124 (-4.2A) CU A1124 (-2.8A)	1.00A	2xxgC-4bxvA: 5.1	2xxgC-4bxvA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	4bxv	PSEUDOAZURIN (Paracoccus pantotrophus)	4 / 5	HIS A 40 CYH A 78 PRO A 80 MET A 86	CU A1124 (-3.5A) CU A1124 (-2.6A) None CU A1124 (-2.8A)	0.95A	2xxgC-4bxvA: 5.1	2xxgC-4bxvA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YV5_A_SVRA205_1 (BASIC PHOSPHOLIPASE A2 HOMOLOG 2)	4bxv	PSEUDOAZURIN (Paracoccus pantotrophus)	4 / 7	ASN A 41 TYR A 74 LEU A 89 PHE A 22	None	1.23A	4yv5A-4bxvA: undetectable	4yv5A-4bxvA: 16.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OE2_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","4bxv","PSEUDOAZURIN","Paracoccus pantotrophus",4,"CYH A  78;PRO A  80;HIS A  81;MET A  86"," CU A1124 (-2.6A);None; CU A1124 (-4.2A); CU A1124 (-2.8A)","0.95A","1oe2A-4bxvA:5.7","1oe2A-4bxvA:18.18"],["1OE2_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","4bxv","PSEUDOAZURIN","Paracoccus pantotrophus",4,"HIS A  40;CYH A  78;PRO A  80;MET A  86"," CU A1124 (-3.5A); CU A1124 (-2.6A);None; CU A1124 (-2.8A)","0.89A","1oe2A-4bxvA:5.7","1oe2A-4bxvA:18.18"],["2FQD_A_CUA601_0","BLUE COPPER OXIDASE CUEO","4bxv","PSEUDOAZURIN","Paracoccus pantotrophus",4,"HIS A  40;CYH A  78;HIS A  81;MET A  86"," CU A1124 (-3.5A); CU A1124 (-2.6A); CU A1124 (-4.2A); CU A1124 (-2.8A)","0.57A","2fqdA-4bxvA:undetectable","2fqdA-4bxvA:10.79"],["2FQE_A_CUA601_0","BLUE COPPER OXIDASE CUEO","4bxv","PSEUDOAZURIN","Paracoccus pantotrophus",4,"HIS A  40;CYH A  78;HIS A  81;MET A  86"," CU A1124 (-3.5A); CU A1124 (-2.6A); CU A1124 (-4.2A); CU A1124 (-2.8A)","0.67A","2fqeA-4bxvA:undetectable","2fqeA-4bxvA:10.79"],["2FQG_A_CUA601_0","BLUE COPPER OXIDASE CUEO","4bxv","PSEUDOAZURIN","Paracoccus pantotrophus",4,"HIS A  40;CYH A  78;HIS A  81;MET A  86"," CU A1124 (-3.5A); CU A1124 (-2.6A); CU A1124 (-4.2A); CU A1124 (-2.8A)","0.68A","2fqgA-4bxvA:undetectable","2fqgA-4bxvA:10.79"],["2XXG_C_CUC1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","4bxv","PSEUDOAZURIN","Paracoccus pantotrophus",4,"CYH A  78;PRO A  80;HIS A  81;MET A  86"," CU A1124 (-2.6A);None; CU A1124 (-4.2A); CU A1124 (-2.8A)","1.00A","2xxgC-4bxvA:5.1","2xxgC-4bxvA:18.18"],["2XXG_C_CUC1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","4bxv","PSEUDOAZURIN","Paracoccus pantotrophus",4,"HIS A  40;CYH A  78;PRO A  80;MET A  86"," CU A1124 (-3.5A); CU A1124 (-2.6A);None; CU A1124 (-2.8A)","0.95A","2xxgC-4bxvA:5.1","2xxgC-4bxvA:18.18"],["4YV5_A_SVRA205_1","BASIC PHOSPHOLIPASE A2 HOMOLOG 2","4bxv","PSEUDOAZURIN","Paracoccus pantotrophus",4,"ASN A  41;TYR A  74;LEU A  89;PHE A  22","None","1.23A","4yv5A-4bxvA:undetectable","4yv5A-4bxvA:16.30"]]