SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bxx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 4bxx TRANSCRIPTION FACTOR
BYE1
(Saccharomyces
cerevisiae) 		5 / 12 LEU X 309
PHE X 245
LEU X 313
LEU X 330
VAL X 325
 None
 1.35A 2qd4A-4bxxX:
undetectable		 2qd4A-4bxxX:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 4bxx TRANSCRIPTION FACTOR
BYE1
(Saccharomyces
cerevisiae) 		4 / 5 ASN X 281
LEU X 332
LEU X 309
ASN X 339
 None
 1.09A 4n09C-4bxxX:
undetectable		 4n09C-4bxxX:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 4bxx TRANSCRIPTION FACTOR
BYE1
(Saccharomyces
cerevisiae) 		5 / 12 PHE X 278
LEU X 330
LEU X 335
PHE X 249
LEU X 319
 None
 0.90A 5iepA-4bxxX:
undetectable		 5iepA-4bxxX:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4bxx TRANSCRIPTION FACTOR
BYE1
(Saccharomyces
cerevisiae) 		3 / 3 GLU X 285
TYR X 287
ARG X 238
 None
 0.81A 5uunA-4bxxX:
undetectable		 5uunA-4bxxX:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4bxx TRANSCRIPTION FACTOR
BYE1
(Saccharomyces
cerevisiae) 		3 / 3 GLU X 285
TYR X 287
ARG X 238
 None
 0.71A 5uunB-4bxxX:
undetectable		 5uunB-4bxxX:
16.44