SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bz0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AQI_B_CHDB5_0 (FERROCHELATASE)	4bz0	PUTATIVE TYPE IV PILUS BIOSYNTHESIS PROTEIN (Burkholderia pseudomallei)	3 / 3	PRO A 186 LEU A 43 ARG A 61	None	0.72A	3aqiB-4bz0A: undetectable	3aqiB-4bz0A: 21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BQF_A_QPSA951_1 (ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC)	4bz0	PUTATIVE TYPE IV PILUS BIOSYNTHESIS PROTEIN (Burkholderia pseudomallei)	4 / 6	GLY A 16 TRP A 123 GLU A 129 ARG A 133	None	1.23A	4bqfA-4bz0A: undetectable	4bqfA-4bz0A: 12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PCL_B_SAMB301_0 (O-METHYLTRANSFERASE FAMILY PROTEIN)	4bz0	PUTATIVE TYPE IV PILUS BIOSYNTHESIS PROTEIN (Burkholderia pseudomallei)	5 / 12	LEU A 168 GLY A 83 ALA A 93 ASN A 144 TYR A 86	None	1.31A	4pclB-4bz0A: undetectable	4pclB-4bz0A: 21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RRW_C_LURC705_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4bz0	PUTATIVE TYPE IV PILUS BIOSYNTHESIS PROTEIN (Burkholderia pseudomallei)	5 / 12	LEU A 39 LEU A 17 GLY A 56 ALA A 55 LEU A 22	None K A1191 ( 4.1A) None None None	1.03A	4rrwC-4bz0A: undetectable	4rrwC-4bz0A: 16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RRZ_C_LURC705_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4bz0	PUTATIVE TYPE IV PILUS BIOSYNTHESIS PROTEIN (Burkholderia pseudomallei)	5 / 12	LEU A 39 LEU A 17 GLY A 56 ALA A 55 LEU A 22	None K A1191 ( 4.1A) None None None	1.03A	4rrzC-4bz0A: undetectable	4rrzC-4bz0A: 16.15

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3AQI_B_CHDB5_0","FERROCHELATASE","4bz0","PUTATIVE TYPE IV PILUS BIOSYNTHESIS PROTEIN","Burkholderia pseudomallei",3,"PRO A 186;LEU A  43;ARG A  61","None","0.72A","3aqiB-4bz0A:undetectable","3aqiB-4bz0A:21.78"],["4BQF_A_QPSA951_1","ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC","4bz0","PUTATIVE TYPE IV PILUS BIOSYNTHESIS PROTEIN","Burkholderia pseudomallei",4,"GLY A  16;TRP A 123;GLU A 129;ARG A 133","None","1.23A","4bqfA-4bz0A:undetectable","4bqfA-4bz0A:12.43"],["4PCL_B_SAMB301_0","O-METHYLTRANSFERASE FAMILY PROTEIN","4bz0","PUTATIVE TYPE IV PILUS BIOSYNTHESIS PROTEIN","Burkholderia pseudomallei",5,"LEU A 168;GLY A  83;ALA A  93;ASN A 144;TYR A  86","None","1.31A","4pclB-4bz0A:undetectable","4pclB-4bz0A:21.94"],["4RRW_C_LURC705_1","PROSTAGLANDIN G\/H SYNTHASE 2","4bz0","PUTATIVE TYPE IV PILUS BIOSYNTHESIS PROTEIN","Burkholderia pseudomallei",5,"LEU A  39;LEU A  17;GLY A  56;ALA A  55;LEU A  22","None;  K A1191 ( 4.1A);None;None;None","1.03A","4rrwC-4bz0A:undetectable","4rrwC-4bz0A:16.15"],["4RRZ_C_LURC705_1","PROSTAGLANDIN G\/H SYNTHASE 2","4bz0","PUTATIVE TYPE IV PILUS BIOSYNTHESIS PROTEIN","Burkholderia pseudomallei",5,"LEU A  39;LEU A  17;GLY A  56;ALA A  55;LEU A  22","None;  K A1191 ( 4.1A);None;None;None","1.03A","4rrzC-4bz0A:undetectable","4rrzC-4bz0A:16.15"]]