SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1USQ_F_CLMF1144_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4bz1	FAB 3E31 HEAVY CHAIN (Mus musculus)	5 / 7	GLY H 54 PRO H 53 THR H 58 ILE H 51 GLY H 56	None	1.33A	1usqF-4bz1H: undetectable	1usqF-4bz1H: 21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKJ_E_CLME1141_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4bz1	FAB 3E31 HEAVY CHAIN (Mus musculus)	5 / 7	GLY H 54 PRO H 53 THR H 58 ILE H 51 GLY H 56	None	1.34A	2jkjE-4bz1H: undetectable	2jkjE-4bz1H: 21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKL_E_CLME1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	4bz1	FAB 3E31 HEAVY CHAIN (Mus musculus)	5 / 7	GLY H 54 PRO H 53 THR H 58 ILE H 51 GLY H 56	None	1.33A	2jklE-4bz1H: undetectable	2jklE-4bz1H: 21.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4M7K_H_ACTH302_0 (10H10 HEAVY CHAIN)	4bz1	FAB 3E31 HEAVY CHAIN (Mus musculus)	4 / 5	VAL H 2 TYR H 27 ARG H 98 TYR H 106	None	0.19A	4m7kH-4bz1H: 26.9	4m7kH-4bz1H: 69.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MTH_A_ACTA302_0 (ANTIBODY FAB HEAVY CHAIN)	4bz1	FAB 3E31 HEAVY CHAIN (Mus musculus)	4 / 5	SER H 116 ALA H 118 PHE H 150 LEU H 174	None	0.33A	5mthA-4bz1H: 29.0	5mthA-4bz1H: 82.27

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1USQ_F_CLMF1144_0","DR HEMAGGLUTININ STRUCTURAL SUBUNIT","4bz1","FAB 3E31 HEAVY CHAIN","Mus musculus",5,"GLY H  54;PRO H  53;THR H  58;ILE H  51;GLY H  56","None","1.33A","1usqF-4bz1H:undetectable","1usqF-4bz1H:21.46"],["2JKJ_E_CLME1141_0","DR HEMAGGLUTININ STRUCTURAL SUBUNIT","4bz1","FAB 3E31 HEAVY CHAIN","Mus musculus",5,"GLY H  54;PRO H  53;THR H  58;ILE H  51;GLY H  56","None","1.34A","2jkjE-4bz1H:undetectable","2jkjE-4bz1H:21.46"],["2JKL_E_CLME1143_0","DR HEMAGGLUTININ STRUCTURAL SUBUNIT","4bz1","FAB 3E31 HEAVY CHAIN","Mus musculus",5,"GLY H  54;PRO H  53;THR H  58;ILE H  51;GLY H  56","None","1.33A","2jklE-4bz1H:undetectable","2jklE-4bz1H:21.46"],["4M7K_H_ACTH302_0","10H10 HEAVY CHAIN","4bz1","FAB 3E31 HEAVY CHAIN","Mus musculus",4,"VAL H   2;TYR H  27;ARG H  98;TYR H 106","None","0.19A","4m7kH-4bz1H:26.9","4m7kH-4bz1H:69.30"],["5MTH_A_ACTA302_0","ANTIBODY FAB HEAVY CHAIN","4bz1","FAB 3E31 HEAVY CHAIN","Mus musculus",4,"SER H 116;ALA H 118;PHE H 150;LEU H 174","None","0.33A","5mthA-4bz1H:29.0","5mthA-4bz1H:82.27"]]