SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bz2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 4bz2 FAB 2D73 HEAVY CHAIN
(Mus
musculus) 		4 / 6 VAL H  48
GLY H  49
LEU H  70
GLU H  82
 None
 1.02A 1fduD-4bz2H:
undetectable		 1fduD-4bz2H:
19.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 4bz2 FAB 2D73 HEAVY CHAIN
(Mus
musculus) 		4 / 7 ARG H  98
TYR H 101
TYR H  54
TYR H  52
 None
 0.86A 2ajvH-4bz2H:
23.2
2ajvL-4bz2H:
15.6		 2ajvH-4bz2H:
63.06
2ajvL-4bz2H:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4bz2 FAB 2D73 HEAVY CHAIN
(Mus
musculus) 		3 / 3 ASN H  33
ARG H  99
ASP H 104
 None
PEG  H 226 (-3.0A)
None
 0.89A 2qe6A-4bz2H:
undetectable		 2qe6A-4bz2H:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4bz2 FAB 2D73 HEAVY CHAIN
(Mus
musculus) 		3 / 3 ASN H  33
ARG H  99
ASP H 104
 None
PEG  H 226 (-3.0A)
None
 0.88A 2qe6B-4bz2H:
undetectable		 2qe6B-4bz2H:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4bz2 FAB 2D73 HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER H 211
ALA H 206
VAL H 205
 None
 0.58A 5eypA-4bz2H:
undetectable		 5eypA-4bz2H:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4bz2 FAB 2D73 HEAVY CHAIN
(Mus
musculus) 		3 / 3 TYR H  27
ARG H  77
THR H  30
 None
GOL  H 228 (-3.3A)
None
 0.64A 5z84J-4bz2H:
undetectable		 5z84J-4bz2H:
16.13