SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bza'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4bza TRANSLOCATION AND
ASSEMBLY MODULE TAMA
(Escherichia
coli) 		5 / 10 LEU A 105
ALA A 177
ILE A 106
ALA A  71
LEU A  35
 None
 1.14A 1xp0A-4bzaA:
undetectable		 1xp0A-4bzaA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 4bza TRANSLOCATION AND
ASSEMBLY MODULE TAMA
(Escherichia
coli) 		4 / 8 LEU A 127
LEU A 113
ASP A 120
ASP A 122
 None
 1.03A 2j2pA-4bzaA:
undetectable
2j2pB-4bzaA:
undetectable		 2j2pA-4bzaA:
22.30
2j2pB-4bzaA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 4bza TRANSLOCATION AND
ASSEMBLY MODULE TAMA
(Escherichia
coli) 		5 / 12 GLY A  68
ALA A  71
ILE A  65
LEU A  35
VAL A  39
 None
 1.28A 4azsA-4bzaA:
undetectable		 4azsA-4bzaA:
18.12