SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bzg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 8 HIS A 101
LEU A  63
THR A  62
HIS A 177
 MAL  A 500 (-4.4A)
MAL  A 500 ( 4.5A)
MAL  A 500 (-4.1A)
MAL  A 500 (-4.0A)
 1.02A 1azmA-4bzgA:
undetectable		 1azmA-4bzgA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 7 PHE A  80
PRO A 171
PHE A  89
PHE A 139
 None
 1.30A 1lqtA-4bzgA:
undetectable		 1lqtA-4bzgA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 7 PHE A  80
PRO A 171
PHE A  89
PHE A 139
 None
 1.29A 1lquA-4bzgA:
undetectable		 1lquA-4bzgA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 12 MET A 147
HIS A 159
SER A 316
ILE A  66
TYR A 259
 None
 1.43A 1ot7B-4bzgA:
undetectable		 1ot7B-4bzgA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 8 THR A 178
GLY A  65
GLN A  46
ILE A  66
VAL A  35
 None
 1.46A 1rxcB-4bzgA:
undetectable		 1rxcB-4bzgA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 8 THR A 178
GLY A  65
GLN A  46
ILE A  66
VAL A  35
 None
 1.45A 1rxcE-4bzgA:
undetectable		 1rxcE-4bzgA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 6 HIS A  99
ASN A  92
ASN A  98
GLU A  93
 None
None
None
MAL  A 500 (-3.7A)
 1.44A 3galA-4bzgA:
undetectable		 3galA-4bzgA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_A_9PLA1_1
(CYTOCHROME P450 2A13)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 9 PHE A  80
ALA A 291
PHE A 139
PHE A  89
LEU A 303
 None
 1.44A 3t3sA-4bzgA:
undetectable		 3t3sA-4bzgA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		3 / 3 THR A 312
VAL A 162
GLU A 310
 None
 0.63A 3v4tA-4bzgA:
undetectable
3v4tD-4bzgA:
undetectable		 3v4tA-4bzgA:
21.36
3v4tD-4bzgA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 8 HIS A 101
LEU A  63
THR A  62
HIS A 177
 MAL  A 500 (-4.4A)
MAL  A 500 ( 4.5A)
MAL  A 500 (-4.1A)
MAL  A 500 (-4.0A)
 1.02A 3w6hA-4bzgA:
undetectable		 3w6hA-4bzgA:
22.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BZF_B_ACTB502_0
(ALDOSE 1-EPIMERASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 4 HIS A 101
HIS A 177
ASP A 230
TYR A 271
 MAL  A 500 (-4.4A)
MAL  A 500 (-4.0A)
MAL  A 500 (-2.7A)
MAL  A 500 (-3.9A)
 0.16A 4bzfB-4bzgA:
56.7		 4bzfB-4bzgA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 8 THR A 178
GLY A  65
GLN A  46
ILE A  66
VAL A  35
 None
 1.44A 4e1vA-4bzgA:
undetectable		 4e1vA-4bzgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 8 THR A 178
GLY A  65
GLN A  46
ILE A  66
VAL A  35
 None
 1.43A 4e1vC-4bzgA:
undetectable		 4e1vC-4bzgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 8 THR A 178
GLY A  65
GLN A  46
ILE A  66
VAL A  35
 None
 1.42A 4e1vD-4bzgA:
undetectable		 4e1vD-4bzgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 8 THR A 178
GLY A  65
GLN A  46
ILE A  66
VAL A  35
 None
 1.39A 4e1vE-4bzgA:
undetectable		 4e1vE-4bzgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 8 THR A 178
GLY A  65
GLN A  46
ILE A  66
VAL A  35
 None
 1.41A 4e1vG-4bzgA:
undetectable		 4e1vG-4bzgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 8 THR A 178
GLY A  65
GLN A  46
ILE A  66
VAL A  35
 None
 1.40A 4e1vH-4bzgA:
undetectable		 4e1vH-4bzgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 6 GLU A  93
ILE A  91
ASN A  92
VAL A 292
 MAL  A 500 (-3.7A)
None
None
None
 1.03A 4ejwB-4bzgA:
undetectable		 4ejwB-4bzgA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 12 LEU A 209
LEU A 218
PHE A 233
PRO A 213
ASP A 230
 None
None
None
None
MAL  A 500 (-2.7A)
 1.47A 4j7xJ-4bzgA:
undetectable		 4j7xJ-4bzgA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		5 / 6 ILE A  66
PRO A  67
HIS A 106
ILE A 127
VAL A 145
 None
 1.49A 4zj8A-4bzgA:
undetectable		 4zj8A-4bzgA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		3 / 3 TYR A 259
SER A 317
TRP A 268
 None
 0.88A 5n8jB-4bzgA:
2.4		 5n8jB-4bzgA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		3 / 3 TYR A 259
SER A 317
TRP A 268
 None
 0.90A 5n8jA-4bzgA:
2.4		 5n8jA-4bzgA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		3 / 3 TYR A 259
SER A 317
TRP A 268
 None
 0.97A 5n8jD-4bzgA:
2.4		 5n8jD-4bzgA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 5 ALA A 143
VAL A 145
PHE A 170
ILE A 174
 None
 0.97A 5of1A-4bzgA:
undetectable		 5of1A-4bzgA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 4bzg ALDOSE 1-EPIMERASE
(Bacillus
subtilis) 		4 / 5 ALA A 143
VAL A 145
PHE A 170
ILE A 174
 None
 1.00A 5of1B-4bzgA:
undetectable		 5of1B-4bzgA:
13.19