SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4bzj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 4bzj PROTEIN TRANSPORT
PROTEIN SEC13
(Saccharomyces
cerevisiae) 		4 / 8 ALA B 145
GLY B 176
LYS B 183
ALA B 143
 None
 0.83A 2vh3B-4bzjB:
undetectable		 2vh3B-4bzjB:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 4bzj PROTEIN TRANSPORT
PROTEIN SEC13
(Saccharomyces
cerevisiae) 		5 / 11 SER B 213
ALA B 211
LEU B 248
SER B 261
LEU B 269
 None
 1.06A 2xn5A-4bzjB:
undetectable		 2xn5A-4bzjB:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 4bzj PROTEIN TRANSPORT
PROTEIN SEC13
(Saccharomyces
cerevisiae) 		4 / 7 ILE B 141
HIS B 144
LYS B 183
TYR B 187
 None
 1.11A 3eteD-4bzjB:
undetectable
3eteF-4bzjB:
undetectable		 3eteD-4bzjB:
20.00
3eteF-4bzjB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 4bzj PROTEIN TRANSPORT
PROTEIN SEC13
(Saccharomyces
cerevisiae) 		4 / 8 VAL B  97
ILE B 140
SER B 120
ALA B 143
 None
 1.00A 4eyzA-4bzjB:
undetectable		 4eyzA-4bzjB:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 4bzj PROTEIN TRANSPORT
PROTEIN SEC13
(Saccharomyces
cerevisiae) 		4 / 8 VAL B  97
ILE B 140
SER B 120
ALA B 143
 None
 0.98A 4eyzB-4bzjB:
undetectable		 4eyzB-4bzjB:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RUJ_A_VDXA501_1
(VITAMIN D3 RECEPTOR
A)		 4bzj PROTEIN TRANSPORT
PROTEIN SEC13
(Saccharomyces
cerevisiae) 		5 / 12 VAL B  59
SER B  74
SER B 101
TRP B  57
HIS B   8
 None
 1.48A 4rujA-4bzjB:
undetectable		 4rujA-4bzjB:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 4bzj PROTEIN TRANSPORT
PROTEIN SEC13
(Saccharomyces
cerevisiae) 		3 / 3 TRP B  61
ARG B  23
LEU B  49
 None
 0.86A 5dbyA-4bzjB:
undetectable		 5dbyA-4bzjB:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 4bzj PROTEIN TRANSPORT
PROTEIN SEC13
(Saccharomyces
cerevisiae) 		3 / 3 GLU B  41
HIS B  43
VAL B   2
 None
 0.91A 5trqB-4bzjB:
undetectable		 5trqB-4bzjB:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4bzj PROTEIN TRANSPORT
PROTEIN SEC13
(Saccharomyces
cerevisiae) 		4 / 5 GLN B 236
THR B 235
HIS B 203
LEU B 200
 None
 1.42A 6aphA-4bzjB:
undetectable		 6aphA-4bzjB:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 4bzj PROTEIN TRANSPORT
PROTEIN SEC13
(Saccharomyces
cerevisiae) 		4 / 5 GLN B 236
THR B 235
HIS B 203
LEU B 200
 None
 1.41A 6gbnB-4bzjB:
undetectable		 6gbnB-4bzjB:
21.57