SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c0g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4c0g CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 8 PHE A 742
ILE A 715
TYR A 744
LEU A 747
 None
 0.95A 3rqwI-4c0gA:
undetectable
3rqwJ-4c0gA:
undetectable		 3rqwI-4c0gA:
14.43
3rqwJ-4c0gA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4c0g CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 5 LEU A 671
PHE A 673
LEU A 666
PHE A 662
 None
 1.14A 5iy5P-4c0gA:
undetectable
5iy5W-4c0gA:
undetectable		 5iy5P-4c0gA:
19.83
5iy5W-4c0gA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4c0g CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 6 LEU A 671
PHE A 673
LEU A 666
PHE A 662
 None
 1.06A 5w97C-4c0gA:
undetectable
5w97J-4c0gA:
undetectable		 5w97C-4c0gA:
19.83
5w97J-4c0gA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4c0g CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 5 LEU A 671
PHE A 673
LEU A 666
PHE A 662
 None
 1.11A 5x1fC-4c0gA:
undetectable
5x1fJ-4c0gA:
undetectable		 5x1fC-4c0gA:
19.83
5x1fJ-4c0gA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4c0g CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 5 LEU A 671
PHE A 673
LEU A 666
PHE A 662
 None
 1.15A 5xdxC-4c0gA:
undetectable
5xdxJ-4c0gA:
undetectable		 5xdxC-4c0gA:
19.83
5xdxJ-4c0gA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4c0g CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 5 LEU A 671
PHE A 673
LEU A 666
PHE A 662
 None
 1.13A 5xdxP-4c0gA:
undetectable
5xdxW-4c0gA:
undetectable		 5xdxP-4c0gA:
19.83
5xdxW-4c0gA:
16.09