SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y1P_A_ACTA803_0
(ALDEHYDE REDUCTASE
II)		 4c0n 2-ON-2 HEMOGLOBIN
(Arabidopsis
thaliana) 		4 / 4 HIS A 105
GLU A 109
GLN A 106
PHE A 142
 None
 1.44A 1y1pA-4c0nA:
0.0		 1y1pA-4c0nA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 4c0n 2-ON-2 HEMOGLOBIN
(Arabidopsis
thaliana) 		5 / 12 HIS A 139
SER A   9
ALA A 146
ILE A  95
LEU A 150
 None
None
None
CL  A1152 (-4.1A)
None
 1.35A 3lcvB-4c0nA:
undetectable		 3lcvB-4c0nA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 4c0n 2-ON-2 HEMOGLOBIN
(Arabidopsis
thaliana) 		4 / 5 ILE A  68
ARG A  88
TYR A  72
GLU A  73
 None
 0.93A 4zzcE-4c0nA:
2.3		 4zzcE-4c0nA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4c0n 2-ON-2 HEMOGLOBIN
(Arabidopsis
thaliana) 		5 / 12 GLU A 149
VAL A 145
HIS A 105
ALA A 108
GLY A  13
 None
None
None
HEM  A1157 ( 3.9A)
None
 1.13A 5syeB-4c0nA:
undetectable		 5syeB-4c0nA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 4c0n 2-ON-2 HEMOGLOBIN
(Arabidopsis
thaliana) 		4 / 8 GLY A  32
GLN A  34
LEU A  33
THR A  35
 None
 0.95A 5syjB-4c0nA:
undetectable		 5syjB-4c0nA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 4c0n 2-ON-2 HEMOGLOBIN
(Arabidopsis
thaliana) 		4 / 7 SER A 122
ILE A 125
LEU A 119
MET A 115
 None
 0.96A 5u4sA-4c0nA:
undetectable		 5u4sA-4c0nA:
20.66