SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.07A 1dz9A-4c0rA:
undetectable		 1dz9A-4c0rA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 THR A  86
LEU A 211
VAL A 207
ASP A  28
 None
 1.16A 1dz9A-4c0rA:
undetectable		 1dz9A-4c0rA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 LEU A 211
ASN A 217
LEU A 223
LEU A 220
 None
 0.98A 1e7cA-4c0rA:
undetectable		 1e7cA-4c0rA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.09A 1o76B-4c0rA:
undetectable		 1o76B-4c0rA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 PHE A 196
LEU A 211
VAL A  35
ILE A  65
 None
 0.82A 1p2yA-4c0rA:
undetectable		 1p2yA-4c0rA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.03A 1t85A-4c0rA:
undetectable		 1t85A-4c0rA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.02A 1uyuA-4c0rA:
undetectable		 1uyuA-4c0rA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 THR A  86
LEU A 211
VAL A 207
ASP A  28
 None
 1.14A 1uyuA-4c0rA:
undetectable		 1uyuA-4c0rA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.10A 1uyuB-4c0rA:
undetectable		 1uyuB-4c0rA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 THR A  86
LEU A 211
VAL A 207
ASP A  28
 None
 1.14A 1uyuB-4c0rA:
undetectable		 1uyuB-4c0rA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.03A 1yrcA-4c0rA:
undetectable		 1yrcA-4c0rA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.00A 2feuB-4c0rA:
undetectable		 2feuB-4c0rA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.00A 3fwfA-4c0rA:
undetectable		 3fwfA-4c0rA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.01A 3fwfB-4c0rA:
undetectable		 3fwfB-4c0rA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.04A 3fwjA-4c0rA:
undetectable		 3fwjA-4c0rA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 4 LEU A 220
ALA A  87
VAL A 192
PRO A  85
 None
 1.18A 3gv1B-4c0rA:
undetectable		 3gv1B-4c0rA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 0.99A 3l63A-4c0rA:
undetectable		 3l63A-4c0rA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.00A 3wrhA-4c0rA:
undetectable		 3wrhA-4c0rA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.04A 3wrjA-4c0rA:
undetectable		 3wrjA-4c0rA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.01A 3wrlA-4c0rA:
undetectable		 3wrlA-4c0rA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.02A 3wrlE-4c0rA:
undetectable		 3wrlE-4c0rA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.03A 3wrmA-4c0rA:
undetectable		 3wrmA-4c0rA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 PHE A 196
LEU A 211
VAL A  35
ILE A  65
 None
 1.01A 4l4cB-4c0rA:
undetectable		 4l4cB-4c0rA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 0.99A 4l4eA-4c0rA:
undetectable		 4l4eA-4c0rA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 THR A  86
LEU A 211
VAL A 207
ASP A  28
 None
 1.15A 4l4eA-4c0rA:
undetectable		 4l4eA-4c0rA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.01A 4l4fA-4c0rA:
undetectable		 4l4fA-4c0rA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 8 THR A  86
LEU A 211
VAL A 207
ASP A  28
 None
 1.13A 4l4fA-4c0rA:
undetectable		 4l4fA-4c0rA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 1.03A 4l4gA-4c0rA:
undetectable		 4l4gA-4c0rA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 6 ASP A  59
ASN A  78
ALA A  77
TYR A  82
 None
 1.21A 4mdbA-4c0rA:
undetectable		 4mdbA-4c0rA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		5 / 12 LEU A 145
ILE A 170
ILE A 171
VAL A  94
VAL A 181
 GDS  A 500 ( 3.3A)
None
None
None
None
 0.93A 4nkvB-4c0rA:
undetectable		 4nkvB-4c0rA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		5 / 12 LEU A 145
ILE A 170
ILE A 161
VAL A  94
VAL A 181
 GDS  A 500 ( 3.3A)
None
None
None
None
 0.89A 4nkxC-4c0rA:
undetectable		 4nkxC-4c0rA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		5 / 12 LEU A 145
ILE A 170
ILE A 161
VAL A  94
VAL A 181
 GDS  A 500 ( 3.3A)
None
None
None
None
 0.87A 4nkxD-4c0rA:
undetectable		 4nkxD-4c0rA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 6 ALA A   8
GLN A  47
LEU A   7
LEU A  24
 None
CD  A1247 (-2.9A)
None
None
 1.19A 4xoyA-4c0rA:
undetectable		 4xoyA-4c0rA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		3 / 3 ASP A 235
SER A  88
TYR A 191
 None
 0.90A 5glmA-4c0rA:
undetectable		 5glmA-4c0rA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		5 / 10 LEU A 214
ALA A  38
PHE A 206
VAL A 207
PRO A  85
 None
 1.41A 5m0oA-4c0rA:
undetectable		 5m0oA-4c0rA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		4 / 7 THR A  86
LEU A 211
VAL A  35
ASP A  28
 None
 0.96A 5wk9A-4c0rA:
undetectable		 5wk9A-4c0rA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4c0r PUTATIVE AMINO ACID
BINDING PROTEIN
(Streptococcus
mutans) 		3 / 3 LEU A 138
GLN A 125
LYS A 160
 None
None
GDS  A 500 (-2.7A)
 1.00A 6exiA-4c0rA:
undetectable		 6exiA-4c0rA:
15.98