SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c0t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 LEU A 246
VAL A 254
ALA A 267
GLU A 288
GLY A 324
LEU A 371
 None
 0.63A 1iepA-4c0tA:
21.5		 1iepA-4c0tA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		4 / 7 LEU A 304
SER A 303
ASP A 319
PHE A 306
 None
 0.90A 1ismB-4c0tA:
undetectable		 1ismB-4c0tA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M17_A_AQ4A999_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
ALA A 267
LYS A 269
GLU A 288
GLY A 324
LEU A 371
THR A 381
ASP A 382
 None
 0.83A 1m17A-4c0tA:
23.8		 1m17A-4c0tA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUO_A_ADNA1_1
(AURORA-RELATED
KINASE 1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 9 LEU A 246
GLY A 247
VAL A 254
ALA A 267
TYR A 320
ALA A 321
LEU A 371
 None
 0.44A 1muoA-4c0tA:
10.8		 1muoA-4c0tA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_1
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
GLU A 288
LEU A 292
GLY A 324
LEU A 371
 None
 0.80A 1t46A-4c0tA:
22.6		 1t46A-4c0tA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XBB_A_STIA1_1
(TYROSINE-PROTEIN
KINASE SYK)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 9 LEU A 246
VAL A 254
ALA A 267
ALA A 321
GLY A 324
LEU A 371
 None
 0.74A 1xbbA-4c0tA:
23.8		 1xbbA-4c0tA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 ALA A 267
GLY A 324
LEU A 327
LEU A 371
THR A 381
ASP A 382
PHE A 383
 None
 1.06A 1xkkA-4c0tA:
20.8		 1xkkA-4c0tA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 10 LEU A 246
ALA A 267
ILE A 302
LEU A 318
LEU A 371
 None
 0.53A 1yi4A-4c0tA:
28.0		 1yi4A-4c0tA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EVA_A_ADNA498_1
(TAK1 KINASE - TAB1
CHIMERA FUSION
PROTEIN)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 11 GLY A 247
VAL A 254
ALA A 267
TYR A 320
ALA A 321
LEU A 371
 None
 0.39A 2evaA-4c0tA:
22.3		 2evaA-4c0tA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 11 TYR A 354
ILE A 380
LEU A 388
ILE A 361
PHE A 383
 None
 1.28A 2h42A-4c0tA:
undetectable		 2h42A-4c0tA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITY_A_IREA2020_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		9 / 12 LEU A 246
GLY A 247
VAL A 254
ALA A 267
LYS A 269
GLU A 288
GLY A 324
LEU A 371
ASP A 382
 None
 0.95A 2ityA-4c0tA:
23.1		 2ityA-4c0tA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_0
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
GLY A 247
VAL A 254
GLU A 288
LEU A 292
TYR A 320
ALA A 321
ASP A 382
 None
 0.71A 2ivuA-4c0tA:
24.7		 2ivuA-4c0tA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_0
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
GLY A 247
VAL A 254
LYS A 269
LEU A 292
TYR A 320
ALA A 321
 None
 0.51A 2ivuA-4c0tA:
24.7		 2ivuA-4c0tA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_0
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
GLY A 247
VAL A 254
TYR A 320
ALA A 321
LEU A 371
ASP A 382
 None
 0.63A 2ivuA-4c0tA:
24.7		 2ivuA-4c0tA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 ASP A 430
GLY A 429
ILE A 496
GLY A 435
ALA A 351
ILE A 352
 None
 1.46A 2nmzB-4c0tA:
undetectable		 2nmzB-4c0tA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WGJ_A_VGHA2346_1
(HEPATOCYTE GROWTH
FACTOR RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 GLY A 247
VAL A 254
ALA A 267
LEU A 318
TYR A 320
ASP A 382
 None
 0.75A 2wgjA-4c0tA:
22.8		 2wgjA-4c0tA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LYS A 244
ALA A 267
LYS A 269
GLU A 288
TYR A 320
GLY A 324
LEU A 371
 None
 0.88A 2y6oA-4c0tA:
22.5		 2y6oA-4c0tA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_A_B49A1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 VAL A 254
ALA A 267
ILE A 302
GLY A 324
GLU A 325
LEU A 371
ASP A 382
 None
 0.79A 2y7jA-4c0tA:
29.4		 2y7jA-4c0tA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_B_B49B1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 10 VAL A 254
ALA A 267
ILE A 302
GLY A 324
LEU A 371
ASP A 382
 None
 0.77A 2y7jB-4c0tA:
29.6		 2y7jB-4c0tA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BBT_B_FMMB91_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 VAL A 254
ALA A 267
GLY A 324
LEU A 371
THR A 381
ASP A 382
PHE A 383
 None
 0.97A 3bbtB-4c0tA:
20.2		 3bbtB-4c0tA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BBT_D_FMMD91_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 VAL A 254
ALA A 267
GLY A 324
LEU A 371
THR A 381
ASP A 382
PHE A 383
 None
 1.03A 3bbtD-4c0tA:
20.3		 3bbtD-4c0tA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C7Q_A_XINA1172_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 LEU A 246
GLY A 247
ALA A 267
LYS A 269
GLY A 324
LEU A 371
 None
 0.51A 3c7qA-4c0tA:
21.8		 3c7qA-4c0tA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_D_NILD600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		4 / 6 LEU A 246
VAL A 254
LYS A 269
LEU A 371
 None
 0.70A 3cs9D-4c0tA:
20.4		 3cs9D-4c0tA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		4 / 4 ILE A 352
GLN A 347
ILE A 496
LEU A 372
 None
 1.31A 3dzyD-4c0tA:
undetectable		 3dzyD-4c0tA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		4 / 5 ILE A 302
PHE A 240
PHE A 306
TYR A 305
 None
 1.07A 3em0A-4c0tA:
undetectable		 3em0A-4c0tA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUP_B_MI1B1_1
(TYROSINE-PROTEIN
KINASE JAK2)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
GLY A 247
GLY A 249
VAL A 254
ALA A 267
TYR A 320
LEU A 371
 None
 0.48A 3fupB-4c0tA:
23.8		 3fupB-4c0tA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUP_B_MI1B1_1
(TYROSINE-PROTEIN
KINASE JAK2)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
GLY A 247
VAL A 254
ALA A 267
LYS A 269
TYR A 320
LEU A 371
 None
 0.53A 3fupB-4c0tA:
23.8		 3fupB-4c0tA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0E_A_B49A9000_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 11 LEU A 246
VAL A 254
ALA A 267
TYR A 320
GLY A 324
LEU A 371
 None
 0.41A 3g0eA-4c0tA:
21.5		 3g0eA-4c0tA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0F_A_B49A9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 11 LEU A 246
VAL A 254
ALA A 267
TYR A 320
GLY A 324
LEU A 371
 None
 0.41A 3g0fA-4c0tA:
22.8		 3g0fA-4c0tA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0F_B_B49B9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 10 LEU A 246
VAL A 254
ALA A 267
TYR A 320
GLY A 324
LEU A 371
 None
 0.46A 3g0fB-4c0tA:
22.9		 3g0fB-4c0tA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 12 ALA A 267
LYS A 269
GLU A 288
LEU A 292
ILE A 302
 None
 0.80A 3hecA-4c0tA:
22.4		 3hecA-4c0tA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXN_A_MI1A1_1
(NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
GLY A 247
VAL A 254
ALA A 267
LYS A 269
ILE A 302
TYR A 320
LEU A 371
 None
 0.58A 3lxnA-4c0tA:
23.2		 3lxnA-4c0tA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 LEU A 246
VAL A 254
ALA A 267
GLU A 288
GLY A 324
LEU A 371
 None
 0.64A 3ms9B-4c0tA:
21.3		 3ms9B-4c0tA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 LEU A 246
VAL A 254
ALA A 267
GLU A 288
GLY A 324
LEU A 371
 None
 0.66A 3mssB-4c0tA:
21.3		 3mssB-4c0tA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_1
(TYROSINE-PROTEIN
KINASE BTK)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
TYR A 320
GLY A 324
LEU A 371
 None
 0.64A 3octA-4c0tA:
21.3		 3octA-4c0tA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OG7_A_032A1_1
(AKAP9-BRAF FUSION
PROTEIN)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 12 VAL A 254
ALA A 267
LYS A 269
LEU A 292
PHE A 383
 None
 0.72A 3og7A-4c0tA:
22.4		 3og7A-4c0tA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_1
(P38A)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 GLY A 247
VAL A 254
ALA A 267
LYS A 269
LEU A 292
ILE A 302
 None
 0.69A 3ohtA-4c0tA:
5.6		 3ohtA-4c0tA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_1
(P38A)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 GLY A 247
VAL A 254
ALA A 267
LYS A 269
LEU A 292
ILE A 302
 None
 0.71A 3ohtB-4c0tA:
5.6		 3ohtB-4c0tA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QLG_A_1N1A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
GLU A 288
TYR A 320
GLY A 324
LEU A 371
 None
 0.81A 3qlgA-4c0tA:
22.7		 3qlgA-4c0tA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QLG_B_1N1B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
VAL A 254
ALA A 267
GLU A 288
TYR A 320
GLY A 324
LEU A 371
ASP A 382
 None
 0.81A 3qlgB-4c0tA:
22.9		 3qlgB-4c0tA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_1
(CYCLIN-DEPENDENT
KINASE 8)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 VAL A 254
ALA A 267
GLU A 288
LEU A 292
ILE A 302
TYR A 320
ALA A 321
HIS A 362
 None
 0.84A 3rgfA-4c0tA:
5.5		 3rgfA-4c0tA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZE_A_BAXA1201_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
LEU A 292
GLY A 324
HIS A 362
 None
 0.57A 3wzeA-4c0tA:
22.4		 3wzeA-4c0tA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 11 ILE A 437
GLY A 435
PHE A 434
GLY A 345
ARG A 298
 None
 0.94A 4ac9B-4c0tA:
undetectable
4ac9C-4c0tA:
undetectable		 4ac9B-4c0tA:
21.23
4ac9C-4c0tA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 9 ILE A 437
GLY A 435
PHE A 434
GLY A 345
ARG A 298
 None
 0.94A 4acaB-4c0tA:
undetectable
4acaC-4c0tA:
undetectable		 4acaB-4c0tA:
21.23
4acaC-4c0tA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AG8_A_AXIA2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
GLU A 288
GLY A 324
LEU A 371
 None
 0.72A 4ag8A-4c0tA:
22.3		 4ag8A-4c0tA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGC_A_AXIA2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
VAL A 254
ALA A 267
GLU A 288
LEU A 292
GLY A 324
LEU A 371
 None
 0.75A 4agcA-4c0tA:
22.0		 4agcA-4c0tA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGC_A_AXIA2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
LEU A 292
GLY A 324
LEU A 371
 None
 0.60A 4agcA-4c0tA:
22.0		 4agcA-4c0tA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
GLU A 288
LEU A 292
GLY A 324
HIS A 362
 None
 0.71A 4asdA-4c0tA:
22.3		 4asdA-4c0tA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CKJ_A_ADNA2014_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 10 LEU A 246
GLY A 247
GLY A 249
VAL A 254
ALA A 267
TYR A 320
ALA A 321
LEU A 371
 None
 0.56A 4ckjA-4c0tA:
25.3		 4ckjA-4c0tA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HJO_A_AQ4A1001_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
VAL A 254
ALA A 267
GLY A 324
LEU A 371
THR A 381
ASP A 382
 None
 0.88A 4hjoA-4c0tA:
21.5		 4hjoA-4c0tA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I22_A_IREA9001_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
GLY A 247
VAL A 254
ALA A 267
GLY A 324
LEU A 371
THR A 381
ASP A 382
 None
 0.88A 4i22A-4c0tA:
20.4		 4i22A-4c0tA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I22_A_IREA9001_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
GLY A 247
VAL A 254
ALA A 267
LYS A 269
GLY A 324
LEU A 371
THR A 381
 None
 0.80A 4i22A-4c0tA:
20.4		 4i22A-4c0tA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAA_A_RTZA401_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 11 VAL A 254
ALA A 267
LYS A 269
LEU A 318
LEU A 371
 None
 0.42A 4iaaA-4c0tA:
27.7		 4iaaA-4c0tA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFG_A_1E8A601_1
(CALMODULIN-DOMAIN
PROTEIN KINASE 1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 GLY A 247
VAL A 254
ALA A 267
LEU A 304
GLY A 324
GLU A 325
LEU A 371
 None
 0.48A 4ifgA-4c0tA:
23.7		 4ifgA-4c0tA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MKC_A_4MKA1503_1
(ALK TYROSINE KINASE
RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
LEU A 318
GLY A 324
LEU A 371
ASP A 382
 None
 0.87A 4mkcA-4c0tA:
22.8		 4mkcA-4c0tA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXY_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
TYR A 320
GLY A 324
LEU A 371
ASP A 382
 None
 0.97A 4mxyB-4c0tA:
24.0		 4mxyB-4c0tA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXZ_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
TYR A 320
GLY A 324
LEU A 371
ASP A 382
 None
 0.97A 4mxzB-4c0tA:
24.0		 4mxzB-4c0tA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0W_A_ADNA501_1
(AURORA KINASE A)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 6 LEU A 246
GLY A 247
VAL A 254
ALA A 267
LEU A 371
 None
 0.51A 4o0wA-4c0tA:
30.9		 4o0wA-4c0tA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMN_A_DB8A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 ALA A 267
LYS A 269
GLU A 288
TYR A 320
LEU A 371
ASP A 382
 None
 0.72A 4qmnA-4c0tA:
28.4		 4qmnA-4c0tA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMS_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 11 ALA A 267
LYS A 269
GLU A 288
TYR A 320
LEU A 371
ASP A 382
 None
 0.78A 4qmsA-4c0tA:
28.2		 4qmsA-4c0tA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		4 / 6 ALA A 351
ILE A 438
GLY A 345
ILE A 380
 None
 0.69A 4r21A-4c0tA:
undetectable		 4r21A-4c0tA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZ7_A_1E8A901_1
(CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 10 ALA A 267
LYS A 269
ILE A 302
PHE A 316
LEU A 371
 None
 0.58A 4rz7A-4c0tA:
9.6		 4rz7A-4c0tA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 12 ALA A 267
GLU A 288
ALA A 321
HIS A 362
LEU A 371
 None
 0.70A 4tyjA-4c0tA:
22.6		 4tyjA-4c0tA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U0I_A_0LIA1001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 10 LEU A 246
VAL A 254
GLU A 288
LEU A 295
TYR A 320
ILE A 380
 None
 0.87A 4u0iA-4c0tA:
22.6		 4u0iA-4c0tA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U5J_B_RXTB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 9 LEU A 246
VAL A 254
ALA A 267
TYR A 320
GLY A 324
LEU A 371
 None
 0.76A 4u5jB-4c0tA:
24.1		 4u5jB-4c0tA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		4 / 7 ILE A 302
ALA A 321
ARG A 363
ILE A 380
 None
 0.81A 4uxqA-4c0tA:
22.8		 4uxqA-4c0tA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		4 / 7 VAL A 254
ILE A 302
ALA A 321
ILE A 380
 None
 0.35A 4uxqA-4c0tA:
22.8		 4uxqA-4c0tA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 9 LEU A 246
VAL A 254
LYS A 269
ILE A 302
TYR A 320
ARG A 363
LEU A 371
ILE A 380
 None
 0.86A 4v01A-4c0tA:
22.4		 4v01A-4c0tA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 9 LEU A 246
VAL A 254
LYS A 269
TYR A 320
LEU A 371
ILE A 370
 None
 1.22A 4v01A-4c0tA:
22.4		 4v01A-4c0tA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_B_0LIB1770_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 9 LEU A 246
ILE A 302
TYR A 320
ARG A 363
LEU A 371
ILE A 380
 None
 1.01A 4v01B-4c0tA:
22.9		 4v01B-4c0tA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_B_0LIB1770_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 9 LEU A 246
VAL A 254
LYS A 269
ILE A 302
TYR A 320
LEU A 371
ILE A 380
 None
 0.58A 4v01B-4c0tA:
22.9		 4v01B-4c0tA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_B_0LIB1771_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 10 LEU A 246
ILE A 302
TYR A 320
ARG A 363
LEU A 371
ILE A 380
 None
 1.03A 4v04B-4c0tA:
23.3		 4v04B-4c0tA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_B_0LIB1771_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 10 LEU A 246
VAL A 254
LYS A 269
ILE A 302
TYR A 320
LEU A 371
ILE A 380
 None
 0.64A 4v04B-4c0tA:
23.3		 4v04B-4c0tA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WKQ_A_IREA1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
ALA A 267
LYS A 269
GLU A 288
GLY A 324
LEU A 371
THR A 381
 None
 0.84A 4wkqA-4c0tA:
23.4		 4wkqA-4c0tA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 12 ALA A 267
LYS A 269
LEU A 292
ASP A 382
PHE A 383
 None
 0.91A 4xv2B-4c0tA:
22.5		 4xv2B-4c0tA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AAB_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 10 LEU A 246
VAL A 254
ALA A 267
LYS A 269
GLY A 324
LEU A 371
ASP A 382
 None
 0.98A 5aabA-4c0tA:
22.5		 5aabA-4c0tA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BVW_A_1N1A1009_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		9 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
GLU A 288
ILE A 302
TYR A 320
GLY A 324
LEU A 371
 None
 0.71A 5bvwA-4c0tA:
21.7		 5bvwA-4c0tA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 12 VAL A 254
ALA A 267
LYS A 269
LEU A 292
PHE A 383
 None
 0.83A 5cswA-4c0tA:
22.0		 5cswA-4c0tA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 VAL A 254
ALA A 267
ILE A 302
TYR A 320
ALA A 321
PHE A 383
 None
 0.86A 5hesA-4c0tA:
7.1		 5hesA-4c0tA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 VAL A 254
ALA A 267
LYS A 269
TYR A 320
ALA A 321
PHE A 383
 None
 0.69A 5hesB-4c0tA:
21.9		 5hesB-4c0tA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_F_AZ1F2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR-DAR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		4 / 7 GLY A 247
GLY A 249
VAL A 254
LEU A 271
 None
 0.30A 5izjB-4c0tA:
30.2		 5izjB-4c0tA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_G_AZ1G2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 7 GLY A 247
GLY A 249
VAL A 254
LYS A 269
LEU A 271
 None
 0.35A 5izjA-4c0tA:
30.7		 5izjA-4c0tA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J5X_B_AZ1B2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAL-DAR-DAR-
DAR-DAR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		4 / 7 GLY A 247
GLY A 249
VAL A 254
LYS A 269
 None
 0.34A 5j5xA-4c0tA:
30.5		 5j5xA-4c0tA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LVN_A_ADNA402_1
(3-PHOSPHOINOSITIDE-D
EPENDENT PROTEIN
KINASE 1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		9 / 11 LEU A 246
GLY A 247
VAL A 254
ALA A 267
LEU A 318
TYR A 320
ALA A 321
GLU A 325
LEU A 371
 None
 0.50A 5lvnA-4c0tA:
35.3		 5lvnA-4c0tA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_1
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		9 / 12 GLY A 247
VAL A 254
ALA A 267
LYS A 269
GLU A 288
LEU A 318
TYR A 320
GLY A 324
GLU A 325
 None
 0.65A 5mafA-4c0tA:
30.7		 5mafA-4c0tA:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 10 LEU A 246
VAL A 254
LYS A 269
GLU A 288
GLY A 324
 None
 0.56A 5mo4A-4c0tA:
15.8		 5mo4A-4c0tA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N3H_A_NCAA401_0
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 10 LEU A 246
VAL A 254
ALA A 267
TYR A 320
LEU A 371
THR A 381
 None
 0.56A 5n3hA-4c0tA:
30.6		 5n3hA-4c0tA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7Z_A_IREA401_0
(CYCLIN-G-ASSOCIATED
KINASE)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
GLU A 288
GLY A 324
LEU A 371
 None
 0.71A 5y7zA-4c0tA:
26.0		 5y7zA-4c0tA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7Z_A_IREA401_0
(CYCLIN-G-ASSOCIATED
KINASE)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
GLU A 288
GLY A 324
LEU A 371
 None
 0.71A 5y7zA-4c0tA:
26.0		 5y7zA-4c0tA:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA401_0
(CYCLIN-G-ASSOCIATED
KINASE)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
GLU A 288
GLY A 324
LEU A 371
ASP A 382
 None
 0.73A 5y80A-4c0tA:
25.8		 5y80A-4c0tA:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_A_1E8A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
GLY A 247
VAL A 254
ALA A 267
LEU A 371
THR A 381
ASP A 382
 None
 0.89A 5yu9A-4c0tA:
20.4		 5yu9A-4c0tA:
7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_B_1E8B1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 GLY A 247
VAL A 254
ALA A 267
LEU A 371
THR A 381
ASP A 382
 None
 0.81A 5yu9B-4c0tA:
20.6		 5yu9B-4c0tA:
7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_D_1E8D1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		6 / 12 VAL A 254
ALA A 267
GLY A 324
LEU A 371
THR A 381
ASP A 382
 None
 0.87A 5yu9D-4c0tA:
20.5		 5yu9D-4c0tA:
7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
GLY A 247
VAL A 254
ALA A 267
GLU A 288
TYR A 320
ALA A 321
 None
 0.92A 5zv2A-4c0tA:
22.8		 5zv2A-4c0tA:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
VAL A 254
ALA A 267
GLU A 288
TYR A 320
ALA A 321
GLY A 324
 None
 0.50A 5zv2A-4c0tA:
22.8		 5zv2A-4c0tA:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		3 / 3 LYS A 269
LEU A 371
ASP A 382
 None
 0.64A 5zv2A-4c0tA:
22.8		 5zv2A-4c0tA:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		7 / 12 LEU A 246
VAL A 254
ALA A 267
LYS A 269
GLU A 288
ALA A 321
GLY A 324
 None
 0.49A 5zv2B-4c0tA:
22.7		 5zv2B-4c0tA:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		3 / 3 TYR A 320
LEU A 371
ASP A 382
 None
 0.45A 5zv2B-4c0tA:
22.7		 5zv2B-4c0tA:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		8 / 12 VAL A 254
ALA A 267
LYS A 269
GLU A 288
ILE A 302
TYR A 320
GLY A 324
LEU A 371
 None
 0.76A 6bsdA-4c0tA:
21.5		 6bsdA-4c0tA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 4c0t LIKELY PROTEIN
KINASE
(Candida
albicans) 		5 / 12 LYS A 264
THR A 381
ILE A 302
LEU A 371
LEU A 256
 None
 1.24A 6ie8A-4c0tA:
undetectable		 6ie8A-4c0tA:
11.32