SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c0z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 4c0z ANCILLARY PROTEIN 2
(Streptococcus
pyogenes) 		5 / 12 GLY A 116
ILE A 128
GLY A 127
ASN A 122
LEU A 181
 None
 1.12A 3eeyJ-4c0zA:
undetectable		 3eeyJ-4c0zA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 4c0z ANCILLARY PROTEIN 2
(Streptococcus
pyogenes) 		4 / 8 ASP A 129
ASN A 132
ALA A 133
VAL A 136
 None
 0.50A 4zbqA-4c0zA:
undetectable		 4zbqA-4c0zA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 4c0z ANCILLARY PROTEIN 2
(Streptococcus
pyogenes) 		3 / 3 SER A  33
TYR A  36
TYR A  39
 None
 0.90A 5lakA-4c0zA:
undetectable
5lakI-4c0zA:
undetectable		 5lakA-4c0zA:
22.09
5lakI-4c0zA:
2.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 4c0z ANCILLARY PROTEIN 2
(Streptococcus
pyogenes) 		3 / 3 SER A  33
TYR A  36
TYR A  39
 None
 0.84A 5lakC-4c0zA:
undetectable
5lakJ-4c0zA:
undetectable		 5lakC-4c0zA:
22.09
5lakJ-4c0zA:
2.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 4c0z ANCILLARY PROTEIN 2
(Streptococcus
pyogenes) 		4 / 7 ASP A 129
ASN A 132
ALA A 133
LEU A 166
 None
 0.96A 6ci6A-4c0zA:
undetectable		 6ci6A-4c0zA:
20.35