SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 9 GLU B  52
ARG B 293
ILE B 246
ALA B 212
ILE B 210
 None
 1.09A 1aj6A-4c1nB:
undetectable		 1aj6A-4c1nB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.36A 1d4fC-4c1nB:
undetectable		 1d4fC-4c1nB:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 9 GLY I 355
ALA I 322
THR I 299
THR I 302
ILE I 308
 None
 1.14A 1gtfD-4c1nI:
undetectable
1gtfE-4c1nI:
undetectable		 1gtfD-4c1nI:
10.47
1gtfE-4c1nI:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY B 129
VAL B  96
ASP B  55
SER B 156
LEU B  19
 None
 1.27A 1kiaD-4c1nB:
undetectable		 1kiaD-4c1nB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 ILE I 450
LEU I 559
GLY I 448
GLY I 446
LEU I 558
 None
 0.98A 1liiA-4c1nI:
undetectable		 1liiA-4c1nI:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 7 LEU A 301
LEU A 308
ILE B 217
GLU B 255
 None
 1.05A 1n13I-4c1nA:
undetectable
1n13L-4c1nA:
undetectable		 1n13I-4c1nA:
9.74
1n13L-4c1nA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 10 SER I 359
GLY I 297
SER I 574
ASP I 212
ILE I 213
 None
 1.26A 1pw7A-4c1nI:
undetectable		 1pw7A-4c1nI:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 244
ILE I 345
GLY I 297
ASN I 298
ILE I 213
 None
 1.16A 1q8jB-4c1nI:
undetectable		 1q8jB-4c1nI:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		5 / 12 ILE A 229
LEU A 230
VAL A  61
GLY A 288
ALA A 287
 None
 1.08A 1r9oA-4c1nA:
undetectable		 1r9oA-4c1nA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		5 / 12 ILE A 159
ALA A 146
GLY A 162
GLY A 135
LEU A 167
 None
 1.06A 1rjdA-4c1nA:
undetectable		 1rjdA-4c1nA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		5 / 12 ILE A 159
ALA A 146
GLY A 162
GLY A 135
LEU A 167
 None
 1.07A 1rjdB-4c1nA:
undetectable		 1rjdB-4c1nA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		5 / 12 ILE A 159
ALA A 146
GLY A 162
GLY A 135
LEU A 167
 None
 1.04A 1rjdC-4c1nA:
undetectable		 1rjdC-4c1nA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		3 / 3 LEU B 309
HIS B 304
ILE A 237
 None
 0.47A 1s9pB-4c1nB:
undetectable		 1s9pB-4c1nB:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 VAL B 243
CYH B  83
ALA B  88
ALA B  92
VAL B  53
 None
 1.03A 1sa1A-4c1nB:
undetectable
1sa1B-4c1nB:
undetectable		 1sa1A-4c1nB:
22.32
1sa1B-4c1nB:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 VAL B 243
CYH B  83
ALA B  88
ALA B  92
VAL B  53
 None
 1.00A 1sa1C-4c1nB:
undetectable
1sa1D-4c1nB:
undetectable		 1sa1C-4c1nB:
22.32
1sa1D-4c1nB:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 7 TYR I 547
THR I 216
THR I 217
MET I 415
 None
 1.01A 1tv8A-4c1nI:
undetectable		 1tv8A-4c1nI:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 5 ALA A 132
TYR A 182
ILE A 159
ASP A 231
 None
 1.26A 1upfA-4c1nA:
undetectable		 1upfA-4c1nA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 5 ILE I 562
LEU I 525
ALA I 534
GLU I 533
 None
 1.13A 1xvaA-4c1nI:
undetectable
1xvaB-4c1nI:
undetectable		 1xvaA-4c1nI:
19.69
1xvaB-4c1nI:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 6 ALA I 534
GLU I 533
ILE I 562
LEU I 525
 None
 0.99A 1xvaA-4c1nI:
undetectable
1xvaB-4c1nI:
undetectable		 1xvaA-4c1nI:
19.69
1xvaB-4c1nI:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 4 LEU A 292
PRO A  91
ILE A 304
LEU A 303
 None
 1.12A 1ya4B-4c1nA:
undetectable		 1ya4B-4c1nA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 4 LEU A 292
PRO A  91
ILE A 304
LEU A 303
 None
 1.07A 1ya4C-4c1nA:
undetectable		 1ya4C-4c1nA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 11 GLY I 577
ALA I 578
ILE I 345
GLY I 355
ILE I 357
 None
 0.87A 2aquB-4c1nI:
undetectable		 2aquB-4c1nI:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 6 THR B 276
VAL B 277
LEU B 213
ALA B 250
 None
 0.92A 2e1qA-4c1nB:
undetectable		 2e1qA-4c1nB:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU I 510
ILE I 468
ASN I 509
ALA I 402
PHE I 403
 None
None
B12  I1631 (-4.2A)
None
None
 1.21A 2ejtA-4c1nI:
undetectable		 2ejtA-4c1nI:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 8 TYR I 547
THR I 216
THR I 217
MET I 415
 None
 0.97A 2fb2A-4c1nI:
undetectable		 2fb2A-4c1nI:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 7 TYR I 547
THR I 216
THR I 217
MET I 415
 None
 1.03A 2fb2B-4c1nI:
undetectable		 2fb2B-4c1nI:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 ASN I 381
ILE I 213
ASN I 238
ALA I 296
ASP I 245
 B12  I1631 (-3.9A)
None
None
None
None
 1.39A 2iyfB-4c1nI:
undetectable		 2iyfB-4c1nI:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 577
ALA I 578
ILE I 345
GLY I 355
ILE I 357
 None
 0.89A 2nmyA-4c1nI:
undetectable		 2nmyA-4c1nI:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		5 / 10 ILE A 159
VAL A 291
ALA A  95
VAL A  66
ILE A  75
 None
 0.99A 2nnjA-4c1nA:
undetectable		 2nnjA-4c1nA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_1
(PROTEASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 11 GLY I 577
ALA I 578
ILE I 345
GLY I 355
ILE I 357
 None
 0.88A 2nnpA-4c1nI:
undetectable		 2nnpA-4c1nI:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 7 ILE I 424
PRO I 441
ILE I 500
ILE I 419
 None
 0.87A 2q83A-4c1nI:
undetectable		 2q83A-4c1nI:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 577
ALA I 578
ILE I 345
GLY I 355
ILE I 357
 None
 0.84A 2qakA-4c1nI:
undetectable		 2qakA-4c1nI:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 4 LEU A 156
PRO A 157
LEU A 130
ARG A 307
 None
 1.13A 2qd2A-4c1nA:
3.8		 2qd2A-4c1nA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 10 ALA I 515
ALA I 519
GLU I 612
ALA I 616
SER I 615
 None
 1.35A 2r2vC-4c1nI:
undetectable
2r2vF-4c1nI:
undetectable
2r2vG-4c1nI:
undetectable		 2r2vC-4c1nI:
6.55
2r2vF-4c1nI:
6.55
2r2vG-4c1nI:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		3 / 3 GLU B 275
GLN B 248
ARG B  94
 None
 0.69A 2w3bB-4c1nB:
undetectable		 2w3bB-4c1nB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.44A 2zj0A-4c1nB:
undetectable		 2zj0A-4c1nB:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 VAL I 538
SER I 568
SER I 573
VAL I 385
LEU I 525
 None
 1.42A 2zlcA-4c1nI:
undetectable		 2zlcA-4c1nI:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 8 THR B 276
VAL B 277
LEU B 213
ALA B 250
 None
 0.98A 3ax7A-4c1nB:
undetectable		 3ax7A-4c1nB:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 9 THR B 276
VAL B 277
LEU B 213
ALA B 253
ALA B 250
 None
 1.07A 3ax7B-4c1nB:
0.6		 3ax7B-4c1nB:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 VAL B 113
ALA B 116
ALA B 146
GLU B 109
THR B  56
 None
 1.30A 3dl9B-4c1nB:
undetectable		 3dl9B-4c1nB:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 577
ALA I 578
ILE I 345
GLY I 355
ILE I 357
 None
 0.90A 3ekqA-4c1nI:
undetectable		 3ekqA-4c1nI:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 577
ALA I 578
ILE I 345
GLY I 355
ILE I 357
 None
 0.84A 3el1B-4c1nI:
undetectable		 3el1B-4c1nI:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 10 GLY I 577
ALA I 578
ILE I 345
GLY I 355
ILE I 357
 None
 0.90A 3el9B-4c1nI:
undetectable		 3el9B-4c1nI:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		3 / 3 ASN A 400
HIS A 401
VAL A 336
 None
 0.90A 3elzB-4c1nA:
undetectable		 3elzB-4c1nA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLN I 240
THR I 302
VAL I 220
LEU I 275
ILE I 211
 None
 1.35A 3elzC-4c1nI:
undetectable		 3elzC-4c1nI:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 7 GLN A 166
GLY A 135
GLU A 106
ALA A 146
 None
 0.75A 3fpjB-4c1nA:
2.0		 3fpjB-4c1nA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 7 LEU I 269
VAL I 295
LEU I 306
LEU I 195
 None
 0.81A 3g8iA-4c1nI:
undetectable		 3g8iA-4c1nI:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.42A 3glqB-4c1nB:
undetectable		 3glqB-4c1nB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU I 231
GLY I 232
LEU I 222
ALA I 210
LEU I 583
 None
 0.86A 3gwvA-4c1nI:
undetectable		 3gwvA-4c1nI:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 THR B 233
LEU B 238
ILE B 224
ILE B 223
LEU B  34
 None
 1.30A 3gwxA-4c1nB:
undetectable		 3gwxA-4c1nB:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 7 ARG B 228
MET B  43
ILE B 283
GLN B 284
 None
 1.01A 3hgxA-4c1nB:
undetectable		 3hgxA-4c1nB:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 7 VAL A 201
TYR A 225
LYS A 198
GLU A 194
 None
 1.29A 3hs4A-4c1nA:
undetectable		 3hs4A-4c1nA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans
;
Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 400
LEU A 373
GLU I 404
ALA I 402
ASN I 509
 B12  I1631 ( 3.8A)
B12  I1631 (-4.1A)
None
None
B12  I1631 (-4.2A)
 1.14A 3kkzA-4c1nI:
undetectable		 3kkzA-4c1nI:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 446
GLY I 407
GLY I 411
GLU I 404
ALA I 402
 None
 1.05A 3kkzB-4c1nI:
undetectable		 3kkzB-4c1nI:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		5 / 10 VAL A  61
GLY A  76
GLN A 246
ILE A 229
GLY A 260
 None
 1.11A 3km6A-4c1nA:
undetectable		 3km6A-4c1nA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		5 / 11 GLN A 244
PRO A 232
ASP A 231
ALA A 132
ILE A 161
 None
 1.35A 3n23A-4c1nA:
undetectable		 3n23A-4c1nA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 ASP I 482
ALA I 505
GLY I 407
VAL I 501
ILE I 408
 None
 1.17A 3n3iA-4c1nI:
undetectable		 3n3iA-4c1nI:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 9 GLY B  87
ALA B  88
ASP B  89
ILE B  90
LEU B  51
 None
 0.69A 3ogpA-4c1nB:
undetectable		 3ogpA-4c1nB:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 9 GLY B  87
ALA B  88
ASP B  89
ILE B  90
LEU B  51
 None
 0.64A 3ogpB-4c1nB:
undetectable		 3ogpB-4c1nB:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 577
ALA I 578
ILE I 345
GLY I 355
ILE I 357
 None
 0.85A 3oxcB-4c1nI:
undetectable		 3oxcB-4c1nI:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		6 / 10 GLY I 297
ALA I 296
ASP I 212
VAL I 294
GLY I 360
VAL I 361
 None
 1.32A 3oxwA-4c1nI:
undetectable		 3oxwA-4c1nI:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 8 ILE A   8
GLN A  31
LEU A   3
LEU A  52
 None
 0.74A 3ozwA-4c1nA:
undetectable		 3ozwA-4c1nA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		5 / 9 ASP A 366
THR A 340
ASN A 341
GLY A 369
ASP A 368
 None
 1.16A 3sfuA-4c1nA:
undetectable		 3sfuA-4c1nA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU I 575
LEU I 582
GLY I 232
LEU I 231
GLN I 221
 None
 1.26A 3tbgA-4c1nI:
undetectable		 3tbgA-4c1nI:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU I 575
LEU I 582
GLY I 232
LEU I 231
GLN I 221
 None
 1.29A 3tbgC-4c1nI:
undetectable		 3tbgC-4c1nI:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 7 THR B 276
VAL B 277
LEU B 213
ALA B 250
 None
 0.98A 3uniA-4c1nB:
undetectable		 3uniA-4c1nB:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 ILE B 210
PHE B 245
ILE B 205
VAL B 176
LEU B 153
 None
 1.14A 3w68C-4c1nB:
undetectable		 3w68C-4c1nB:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 8 VAL I 538
MET I 384
ILE I 376
GLU I 533
 None
 1.06A 4a97C-4c1nI:
undetectable		 4a97C-4c1nI:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CUT_A_TYLA2971_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 4 VAL I 343
VAL I 295
ASN I 273
ILE I 276
 None
 1.11A 4cutA-4c1nI:
undetectable		 4cutA-4c1nI:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 466
SER I 465
ASP I 469
ILE I 468
PHE I 486
 None
 0.84A 4dx5B-4c1nI:
undetectable		 4dx5B-4c1nI:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 8 ALA B 299
GLU B 300
ILE B 272
ILE B  64
 None
 0.86A 4kttB-4c1nB:
undetectable		 4kttB-4c1nB:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.40A 4lvcA-4c1nB:
undetectable		 4lvcA-4c1nB:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.44A 4lvcB-4c1nB:
undetectable		 4lvcB-4c1nB:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 5 LEU A  39
GLY A  38
ILE A   8
LYS A   2
 None
 1.21A 4ma8C-4c1nA:
undetectable		 4ma8C-4c1nA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 7 THR I 373
ARG I 537
PHE I 567
SER I 568
 None
 1.22A 4o4dA-4c1nI:
undetectable		 4o4dA-4c1nI:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 379
GLY I 382
ILE I 540
MET I 384
GLY I 545
 None
 1.07A 4obwB-4c1nI:
undetectable		 4obwB-4c1nI:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLU I 404
GLY I 405
CYH I 445
ALA I 402
ASN I 509
 None
None
None
None
B12  I1631 (-4.2A)
 1.43A 4pclB-4c1nI:
undetectable		 4pclB-4c1nI:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 11 GLY I 577
ALA I 578
ILE I 345
GLY I 355
ILE I 357
 None
 0.91A 4qgiA-4c1nI:
undetectable		 4qgiA-4c1nI:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 466
SER I 465
ASP I 469
ILE I 468
PHE I 486
 None
 0.89A 4u8vB-4c1nI:
undetectable		 4u8vB-4c1nI:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 466
SER I 465
ASP I 469
ILE I 468
PHE I 486
 None
 0.83A 4u8yB-4c1nI:
undetectable		 4u8yB-4c1nI:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY I 466
SER I 465
ASP I 469
ILE I 468
PHE I 486
 None
 0.84A 4u95B-4c1nI:
undetectable		 4u95B-4c1nI:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLU B  52
ARG B 293
ILE B 246
ALA B 212
ILE B 210
 None
 0.92A 4uroC-4c1nB:
undetectable		 4uroC-4c1nB:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY A 428
ILE I 251
GLY A 379
THR A 382
LEU A 413
 B12  I1631 ( 4.0A)
None
None
None
None
 1.18A 4zdyA-4c1nA:
undetectable		 4zdyA-4c1nA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 10 GLY I 355
ALA I 322
THR I 299
THR I 302
ILE I 308
 None
 1.17A 5eevA-4c1nI:
undetectable
5eevB-4c1nI:
undetectable		 5eevA-4c1nI:
10.47
5eevB-4c1nI:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 10 GLY I 355
ALA I 322
THR I 299
THR I 302
ILE I 308
 None
 1.17A 5eexA-4c1nI:
undetectable
5eexB-4c1nI:
undetectable		 5eexA-4c1nI:
10.47
5eexB-4c1nI:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.43A 5hm8A-4c1nB:
undetectable		 5hm8A-4c1nB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 5 GLU A 165
GLU A 172
THR A 173
LEU A 160
 None
 1.11A 5hm8A-4c1nA:
undetectable		 5hm8A-4c1nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.43A 5hm8B-4c1nB:
undetectable		 5hm8B-4c1nB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 5 GLU A 165
GLU A 172
THR A 173
LEU A 160
 None
 1.11A 5hm8B-4c1nA:
undetectable		 5hm8B-4c1nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.43A 5hm8C-4c1nB:
undetectable		 5hm8C-4c1nB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 5 GLU A 165
GLU A 172
THR A 173
LEU A 160
 None
 1.11A 5hm8C-4c1nA:
undetectable		 5hm8C-4c1nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.43A 5hm8D-4c1nB:
undetectable		 5hm8D-4c1nB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 5 GLU A 165
GLU A 172
THR A 173
LEU A 160
 None
 1.11A 5hm8D-4c1nA:
undetectable		 5hm8D-4c1nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.43A 5hm8E-4c1nB:
undetectable		 5hm8E-4c1nB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 5 GLU A 165
GLU A 172
THR A 173
LEU A 160
 None
 1.11A 5hm8E-4c1nA:
undetectable		 5hm8E-4c1nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.43A 5hm8F-4c1nB:
undetectable		 5hm8F-4c1nB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 5 GLU A 165
GLU A 172
THR A 173
LEU A 160
 None
 1.11A 5hm8F-4c1nA:
undetectable		 5hm8F-4c1nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.43A 5hm8G-4c1nB:
undetectable		 5hm8G-4c1nB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 5 GLU A 165
GLU A 172
THR A 173
LEU A 160
 None
 1.15A 5hm8G-4c1nA:
undetectable		 5hm8G-4c1nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.43A 5hm8H-4c1nB:
undetectable		 5hm8H-4c1nB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 5 GLU A 165
GLU A 172
THR A 173
LEU A 160
 None
 1.11A 5hm8H-4c1nA:
2.6		 5hm8H-4c1nA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_G_IPHG101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		4 / 6 LEU A  53
CYH A  42
HIS A  11
LEU A  12
 None
SF4  A1444 (-2.3A)
None
SF4  A1444 ( 4.5A)
 1.38A 5hrqD-4c1nA:
undetectable
5hrqG-4c1nA:
undetectable
5hrqH-4c1nA:
undetectable		 5hrqD-4c1nA:
7.37
5hrqG-4c1nA:
3.76
5hrqH-4c1nA:
7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 5 GLY I 354
THR I 299
GLY I 228
LEU I 575
 None
 0.84A 5jlcA-4c1nI:
undetectable		 5jlcA-4c1nI:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 7 GLY I 577
ALA I 578
GLY I 355
ILE I 357
 None
 0.67A 5kqyB-4c1nI:
undetectable		 5kqyB-4c1nI:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 8 GLY I 577
ALA I 578
GLY I 355
ILE I 357
 None
 0.67A 5kr1B-4c1nI:
undetectable		 5kr1B-4c1nI:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.44A 5m66B-4c1nB:
undetectable		 5m66B-4c1nB:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 7 GLY I 460
GLU I 426
ASP I 469
ASN I 473
 None
 0.99A 5n5dB-4c1nI:
undetectable		 5n5dB-4c1nI:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLU I 289
LEU I 122
ASP I 224
ALA I 292
GLY I 184
 None
 1.23A 5syeB-4c1nI:
undetectable		 5syeB-4c1nI:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		4 / 6 ARG I 585
LEU I 189
PRO I 327
SER I 186
 None
 1.38A 5syjB-4c1nI:
undetectable		 5syjB-4c1nI:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.45A 5utuH-4c1nB:
undetectable		 5utuH-4c1nB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.44A 5v96B-4c1nB:
undetectable		 5v96B-4c1nB:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 4c1n CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU B 305
ASP B  31
GLY B 287
HIS B 288
PHE B  36
 None
 1.45A 5v96C-4c1nB:
undetectable		 5v96C-4c1nB:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU A 156
ILE A  96
ALA A 132
ILE A 264
ALA A 265
 None
 1.21A 5vc0A-4c1nA:
undetectable		 5vc0A-4c1nA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
(Carboxydothermus
hydrogenoformans) 		5 / 12 SER A 137
THR A 185
ALA A 146
ALA A 169
GLU A 165
 None
 1.29A 5vcgA-4c1nA:
undetectable		 5vcgA-4c1nA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN
(Carboxydothermus
hydrogenoformans) 		3 / 3 ILE I 313
ASN I 381
CYH I 395
 None
B12  I1631 (-3.9A)
None
 0.80A 6bp4A-4c1nI:
undetectable		 6bp4A-4c1nI:
20.94