SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 ALA A  20
LEU A   9
ILE A  46
HIS A 225
LEU A 251
 None
 1.43A 1ereA-4c30A:
undetectable		 1ereA-4c30A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 ALA A  20
LEU A   9
ILE A  46
HIS A 225
LEU A 251
 None
 1.44A 1ereB-4c30A:
undetectable		 1ereB-4c30A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 ALA A  20
LEU A   9
ILE A  46
HIS A 225
LEU A 251
 None
 1.44A 1ereC-4c30A:
undetectable		 1ereC-4c30A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 ALA A  20
LEU A   9
ILE A  46
HIS A 225
LEU A 251
 None
 1.45A 1ereD-4c30A:
undetectable		 1ereD-4c30A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 5 HIS A  56
GLU A  59
ALA A 221
HIS A 225
 None
 1.36A 1errA-4c30A:
1.9
1errB-4c30A:
undetectable		 1errA-4c30A:
17.40
1errB-4c30A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.93A 1hpvB-4c30A:
undetectable		 1hpvB-4c30A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A  69
VAL A 226
GLN A 236
ARG A 264
TYR A 261
 None
 1.34A 1kt4A-4c30A:
undetectable		 1kt4A-4c30A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 GLU A 202
GLY A 197
ASP A 195
ILE A 148
ALA A 178
 None
 1.30A 1oltA-4c30A:
undetectable		 1oltA-4c30A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 10 ALA A  20
LEU A   9
ILE A  46
HIS A 225
LEU A 251
 None
 1.43A 1qkuA-4c30A:
undetectable		 1qkuA-4c30A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 10 ALA A  20
LEU A   9
ILE A  46
HIS A 225
LEU A 251
 None
 1.44A 1qkuB-4c30A:
undetectable		 1qkuB-4c30A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 10 ALA A  20
LEU A   9
ILE A  46
HIS A 225
LEU A 251
 None
 1.43A 1qkuC-4c30A:
undetectable		 1qkuC-4c30A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.85A 1rxcB-4c30A:
undetectable		 1rxcB-4c30A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.92A 1rxcE-4c30A:
undetectable		 1rxcE-4c30A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.84A 1rxcI-4c30A:
undetectable		 1rxcI-4c30A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.91A 1rxcK-4c30A:
undetectable		 1rxcK-4c30A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.95A 1sdtB-4c30A:
undetectable		 1sdtB-4c30A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.91A 1sduB-4c30A:
undetectable		 1sduB-4c30A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 VAL A 369
GLU A 336
GLY A 585
TYR A 361
GLN A 588
 None
 1.34A 1vidA-4c30A:
4.2		 1vidA-4c30A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 6 GLU A 646
ASP A 641
PHE A 327
ARG A 329
 None
 1.08A 2a3bB-4c30A:
undetectable		 2a3bB-4c30A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 6 GLU A 649
ASP A 641
PHE A 327
ARG A 329
 None
 1.33A 2a3bB-4c30A:
undetectable		 2a3bB-4c30A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.89A 2avvE-4c30A:
undetectable		 2avvE-4c30A:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 11 ALA A 180
ILE A 125
GLY A 130
ILE A 135
ILE A 144
 None
 0.88A 2b60B-4c30A:
undetectable		 2b60B-4c30A:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.95A 2f81B-4c30A:
undetectable		 2f81B-4c30A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
ILE A 125
GLY A 130
ILE A 135
ILE A 144
 None
 0.99A 2hs1A-4c30A:
undetectable		 2hs1A-4c30A:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.92A 2ienB-4c30A:
undetectable		 2ienB-4c30A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		3 / 3 ASP A 231
ASP A 267
ASP A 255
 None
 0.74A 2igtA-4c30A:
4.5		 2igtA-4c30A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		3 / 3 ASP A 231
ASP A 267
ASP A 255
 None
 0.77A 2igtB-4c30A:
3.4		 2igtB-4c30A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 1.01A 2q5kA-4c30A:
undetectable		 2q5kA-4c30A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.99A 2q63B-4c30A:
undetectable		 2q63B-4c30A:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 11 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.93A 2qhcA-4c30A:
undetectable		 2qhcA-4c30A:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
ILE A 125
GLY A 130
ILE A 135
ILE A 144
 None
 0.94A 2rkgB-4c30A:
undetectable		 2rkgB-4c30A:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 7 ASN A 301
LEU A 297
TYR A 612
THR A 616
 None
 1.17A 2uz2A-4c30A:
undetectable		 2uz2A-4c30A:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 6 LYS A  38
TYR A 612
LEU A 297
ASN A 289
 ANP  A1662 (-2.9A)
None
None
None
 1.37A 2w98A-4c30A:
5.0
2w98B-4c30A:
5.2		 2w98A-4c30A:
18.93
2w98B-4c30A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_B_ACTB501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 6 ASP A 117
ARG A 403
VAL A 412
TYR A 116
 None
 1.08A 2yfbB-4c30A:
undetectable		 2yfbB-4c30A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 THR A  64
ASP A 549
ASP A 541
GLU A  72
 None
 0.90A 2zw9A-4c30A:
4.9		 2zw9A-4c30A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 SER A  90
PHE A  92
ILE A 200
THR A 203
 None
 0.98A 3bpxA-4c30A:
undetectable
3bpxB-4c30A:
undetectable		 3bpxA-4c30A:
14.76
3bpxB-4c30A:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.92A 3d1xB-4c30A:
undetectable		 3d1xB-4c30A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		3 / 3 ASP A 231
ASP A 267
ASP A 255
 None
 0.72A 3douA-4c30A:
2.6		 3douA-4c30A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 11 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.87A 3ekxB-4c30A:
undetectable		 3ekxB-4c30A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 10 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.99A 3ekyA-4c30A:
undetectable		 3ekyA-4c30A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 11 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.95A 3el1A-4c30A:
undetectable		 3el1A-4c30A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 ALA A 402
LEU A 487
VAL A 490
ILE A 395
LEU A 514
 None
 1.20A 3fl9H-4c30A:
undetectable		 3fl9H-4c30A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		3 / 3 ASP A 118
ARG A 145
ARG A 552
 MG  A1664 (-2.9A)
None
None
 0.82A 3k37A-4c30A:
undetectable		 3k37A-4c30A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.96A 3k4vD-4c30A:
undetectable		 3k4vD-4c30A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP4_A_MIIA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 THR A 203
LEU A 100
ALA A  95
HIS A  93
ASN A 233
 None
 1.47A 3kp4A-4c30A:
0.1
3kp4B-4c30A:
2.3		 3kp4A-4c30A:
12.01
3kp4B-4c30A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 11 GLN A 588
PRO A 592
ALA A 299
PHE A 327
ILE A 615
 None
 1.34A 3n23A-4c30A:
undetectable		 3n23A-4c30A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.90A 3nbqC-4c30A:
undetectable		 3nbqC-4c30A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 GLY A 614
MET A 568
LEU A 610
ARG A 617
ILE A 260
 None
None
None
ANP  A1662 (-3.0A)
None
 1.41A 3nbqD-4c30A:
undetectable		 3nbqD-4c30A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.95A 3ndtD-4c30A:
undetectable		 3ndtD-4c30A:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.89A 3nduB-4c30A:
undetectable		 3nduB-4c30A:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.90A 3nduD-4c30A:
undetectable		 3nduD-4c30A:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.95A 3ndwB-4c30A:
undetectable		 3ndwB-4c30A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		6 / 9 ALA A 180
ILE A 125
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 1.11A 3nu4A-4c30A:
undetectable		 3nu4A-4c30A:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 10 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.98A 3nu6B-4c30A:
undetectable		 3nu6B-4c30A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_1
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 1.09A 3nuoA-4c30A:
undetectable		 3nuoA-4c30A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.89A 3oxcA-4c30A:
undetectable		 3oxcA-4c30A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.95A 3oxcB-4c30A:
undetectable		 3oxcB-4c30A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.96A 3pwrA-4c30A:
undetectable		 3pwrA-4c30A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.89A 3pwrB-4c30A:
undetectable		 3pwrB-4c30A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 LEU A 315
ALA A  34
SER A 292
TYR A 612
 None
ANP  A1662 (-3.8A)
None
None
 1.10A 3rodA-4c30A:
undetectable		 3rodA-4c30A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 6 LEU A 286
ASP A 227
LEU A  42
THR A  41
 None
MG  A1663 ( 4.0A)
None
None
 1.12A 3rozA-4c30A:
undetectable		 3rozA-4c30A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 ALA A 180
ILE A 125
GLY A 130
ILE A 135
ILE A 144
 None
 0.98A 3s43A-4c30A:
undetectable		 3s43A-4c30A:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 ALA A 180
ILE A 125
GLY A 130
ILE A 135
ILE A 144
 None
 0.98A 3s45A-4c30A:
undetectable		 3s45A-4c30A:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 11 ALA A 180
ILE A 125
GLY A 130
ILE A 135
ILE A 144
 None
 0.98A 3s53B-4c30A:
undetectable		 3s53B-4c30A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.98A 3tkgB-4c30A:
undetectable		 3tkgB-4c30A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.95A 3tkgC-4c30A:
undetectable		 3tkgC-4c30A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TX2_A_BEZA251_0
(PROBABLE
6-PHOSPHOGLUCONOLACT
ONASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 7 ALA A 520
TRP A 524
MET A 551
ALA A 555
 None
 1.26A 3tx2A-4c30A:
undetectable		 3tx2A-4c30A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		3 / 3 LYS A 188
ARG A 205
LEU A 109
 None
 1.27A 3v4tE-4c30A:
undetectable		 3v4tE-4c30A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ILE A 260
LEU A 645
ILE A 583
LEU A 622
VAL A 296
 None
 1.13A 3w68B-4c30A:
undetectable		 3w68B-4c30A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 GLY A 337
ALA A 335
ILE A 370
VAL A 340
ILE A 359
 None
 1.11A 4aztA-4c30A:
3.9		 4aztA-4c30A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		3 / 3 LYS A 152
THR A 201
ILE A 107
 None
 0.79A 4e0fB-4c30A:
undetectable		 4e0fB-4c30A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.91A 4e1vA-4c30A:
undetectable		 4e1vA-4c30A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.95A 4e1vC-4c30A:
undetectable		 4e1vC-4c30A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.93A 4e1vD-4c30A:
undetectable		 4e1vD-4c30A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.92A 4e1vE-4c30A:
undetectable		 4e1vE-4c30A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 8 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.93A 4e1vH-4c30A:
undetectable		 4e1vH-4c30A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 10 ALA A 180
ILE A 125
GLY A 130
ILE A 135
VAL A 143
 None
 1.07A 4j5jB-4c30A:
undetectable		 4j5jB-4c30A:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 6 ARG A 403
ASP A 117
ASP A 391
ARG A 396
 None
None
MG  A1664 (-3.5A)
None
 1.38A 4kcnB-4c30A:
undetectable		 4kcnB-4c30A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 11 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.95A 4qgiB-4c30A:
undetectable		 4qgiB-4c30A:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 5 GLN A 236
SER A 153
ASP A 195
ASP A 120
 None
 1.24A 4qtuB-4c30A:
4.1		 4qtuB-4c30A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 5 GLN A 236
SER A 153
ASP A 195
ASP A 120
 None
 1.23A 4qtuD-4c30A:
4.5		 4qtuD-4c30A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 5 LEU A 155
SER A 153
ASP A 195
ASP A 120
 None
 1.32A 4qtuD-4c30A:
4.5		 4qtuD-4c30A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 627
ARG A 630
GLY A 585
ALA A 341
GLY A 337
 None
 1.29A 4r29B-4c30A:
undetectable		 4r29B-4c30A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 7 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.92A 4txnA-4c30A:
2.5		 4txnA-4c30A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 7 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.91A 4txnB-4c30A:
undetectable		 4txnB-4c30A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 7 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.89A 4txnC-4c30A:
undetectable		 4txnC-4c30A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 7 THR A  39
GLY A  35
GLN A 258
ARG A 617
 MG  A1663 ( 2.8A)
ANP  A1662 (-3.1A)
ANP  A1662 (-3.2A)
ANP  A1662 (-3.0A)
 0.88A 4txnD-4c30A:
undetectable		 4txnD-4c30A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_C_ANWC601_0
(RHODOPSIN KINASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 6 ARG A 403
LEU A 539
ALA A 542
MET A 551
LEU A 517
 None
 1.47A 4wboC-4c30A:
undetectable		 4wboC-4c30A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 VAL A 369
GLU A 336
GLY A 585
TYR A 361
GLN A 588
 None
 1.32A 4xucA-4c30A:
3.3		 4xucA-4c30A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 VAL A 369
GLU A 336
GLY A 585
TYR A 361
GLN A 588
 None
 1.32A 4xudA-4c30A:
3.0		 4xudA-4c30A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 5 GLU A 185
LYS A 188
ASP A 198
GLU A 202
 None
 1.47A 5a06A-4c30A:
undetectable		 5a06A-4c30A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 7 PHE A 113
ARG A 101
ASP A 540
ILE A 115
 None
 1.30A 5a06B-4c30A:
undetectable		 5a06B-4c30A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 VAL A  63
ILE A  46
LEU A 251
TYR A 284
ALA A  20
 None
 1.44A 5fctB-4c30A:
undetectable		 5fctB-4c30A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 VAL A 369
GLU A 336
GLY A 585
TYR A 361
GLN A 588
 None
 1.35A 5fhrA-4c30A:
3.1		 5fhrA-4c30A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 LEU A 414
ILE A 124
ASP A 195
LEU A 404
ALA A 413
 None
 1.17A 5h5fA-4c30A:
undetectable		 5h5fA-4c30A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 244
ILE A 260
TYR A 261
GLY A 575
PHE A  92
 None
None
None
ANP  A1662 ( 3.7A)
None
 1.29A 5jlcA-4c30A:
undetectable		 5jlcA-4c30A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		3 / 3 LYS A 554
ASP A 550
ARG A 382
 None
 0.97A 5jwaA-4c30A:
undetectable
5jwaH-4c30A:
undetectable		 5jwaA-4c30A:
21.42
5jwaH-4c30A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.87A 5kqxA-4c30A:
undetectable		 5kqxA-4c30A:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 9 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 1.06A 5kr0A-4c30A:
undetectable		 5kr0A-4c30A:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 VAL A 369
GLU A 336
GLY A 585
TYR A 361
GLN A 588
 None
 1.30A 5lsaA-4c30A:
3.9		 5lsaA-4c30A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 10 ILE A 379
ALA A 341
LEU A 344
ILE A 370
ILE A 383
 None
 1.03A 5mvmD-4c30A:
undetectable
5mvmE-4c30A:
undetectable		 5mvmD-4c30A:
9.24
5mvmE-4c30A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 7 GLY A  96
PHE A  92
SER A  90
ARG A 205
 None
 0.93A 5n5dB-4c30A:
3.4		 5n5dB-4c30A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 GLU A 523
LEU A 487
ALA A 521
PHE A 538
ARG A 392
 None
 1.10A 5nd4B-4c30A:
2.1		 5nd4B-4c30A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		3 / 3 VAL A 253
VAL A  30
GLN A  17
 None
None
ANP  A1662 (-3.0A)
 0.66A 5qgjA-4c30A:
undetectable		 5qgjA-4c30A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		3 / 3 VAL A 253
VAL A  30
GLN A  17
 None
None
ANP  A1662 (-3.0A)
 0.67A 5qgmA-4c30A:
undetectable		 5qgmA-4c30A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		3 / 3 VAL A 253
VAL A  30
GLN A  17
 None
None
ANP  A1662 (-3.0A)
 0.67A 5qh0A-4c30A:
undetectable		 5qh0A-4c30A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		3 / 3 VAL A 253
VAL A  30
GLN A  17
 None
None
ANP  A1662 (-3.0A)
 0.65A 5qhaA-4c30A:
undetectable		 5qhaA-4c30A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		3 / 3 VAL A 253
VAL A  30
GLN A  17
 None
None
ANP  A1662 (-3.0A)
 0.67A 5qhhA-4c30A:
undetectable		 5qhhA-4c30A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 10 MET A 624
VAL A 586
GLY A 585
ILE A 359
LEU A 360
 None
 1.05A 5vm8B-4c30A:
undetectable		 5vm8B-4c30A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 5 TYR A 361
GLN A 366
GLY A 388
ILE A 383
 None
 1.27A 6debB-4c30A:
undetectable		 6debB-4c30A:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		5 / 12 ALA A 180
GLY A 130
ILE A 135
VAL A 143
ILE A 144
 None
 0.91A 6difA-4c30A:
undetectable		 6difA-4c30A:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 7 LEU A 122
ASP A 119
ASP A 117
ARG A 145
 None
MG  A1664 ( 3.9A)
None
None
 1.13A 6g31D-4c30A:
undetectable		 6g31D-4c30A:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_E_ZOLE401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4c30 DNA HELICASE II
(Deinococcus
radiodurans) 		4 / 4 LEU A 122
ASP A 119
ASP A 117
ARG A 145
 None
MG  A1664 ( 3.9A)
None
None
 1.27A 6g31E-4c30A:
undetectable		 6g31E-4c30A:
8.87