SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c3h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 11 PHE A1570
ILE A1575
LEU A1019
LEU A1027
LEU A1023
 None
 1.05A 1dtlA-4c3hA:
undetectable		 1dtlA-4c3hA:
7.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 912
VAL A 938
SER A 941
GLN A 942
 None
 0.82A 1e7aB-4c3hA:
undetectable		 1e7aB-4c3hA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 8 PHE A 817
THR A 818
HIS A 617
HIS A 673
 None
 0.91A 1ei6C-4c3hA:
undetectable		 1ei6C-4c3hA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 8 PHE A 817
THR A 818
HIS A 617
HIS A 673
 None
 0.90A 1ei6D-4c3hA:
undetectable		 1ei6D-4c3hA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 4 THR A1623
LEU A1627
LEU A 335
GLN A 332
 None
 1.14A 1fbmA-4c3hA:
2.5		 1fbmA-4c3hA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 125
THR A1605
SER A 207
THR A 209
 None
 0.81A 1ictD-4c3hA:
undetectable		 1ictD-4c3hA:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 7 LEU A1622
THR A1617
GLN A1601
MET A1603
 None
 1.26A 1kglA-4c3hA:
undetectable		 1kglA-4c3hA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 355
GLN A  93
LYS A1624
VAL A1626
 None
 1.32A 1l2iB-4c3hA:
undetectable		 1l2iB-4c3hA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 12 THR A1542
VAL A1549
ASP A1545
VAL A1524
ASN A1560
 None
 1.26A 1n2xA-4c3hA:
undetectable		 1n2xA-4c3hA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA43
(Saccharomyces
cerevisiae) 		4 / 5 LEU G 147
GLY G 146
HIS G 144
ILE G 157
 None
 0.77A 1xf1A-4c3hG:
undetectable		 1xf1A-4c3hG:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA43
(Saccharomyces
cerevisiae) 		4 / 6 LEU G 147
GLY G 146
HIS G 144
ILE G 157
 None
 0.78A 1xf1B-4c3hG:
undetectable		 1xf1B-4c3hG:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 LEU A1313
ILE A1498
LEU A1262
SER A1496
 None
 1.00A 2byoA-4c3hA:
undetectable		 2byoA-4c3hA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 617
ASP A 631
TYR A 624
HIS A 673
 None
 1.39A 2dysA-4c3hA:
undetectable
2dysC-4c3hA:
undetectable		 2dysA-4c3hA:
14.30
2dysC-4c3hA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 7 HIS A 617
ASP A 631
TYR A 624
HIS A 673
 None
 1.41A 2eijA-4c3hA:
2.5
2eijC-4c3hA:
undetectable		 2eijA-4c3hA:
14.30
2eijC-4c3hA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 358
ILE A 430
PHE A 427
GLN A 431
 None
 1.12A 2jc9A-4c3hA:
2.1		 2jc9A-4c3hA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 GLN A 906
LYS A 910
VAL A 908
 None
 0.82A 2jfaB-4c3hA:
undetectable		 2jfaB-4c3hA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 437
GLN A 431
ASN A 400
LEU A 423
 None
 1.10A 2nyrA-4c3hA:
undetectable		 2nyrA-4c3hA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 123
SER A 186
TYR A 337
 None
 0.94A 2q2hA-4c3hA:
undetectable
2q2hB-4c3hA:
undetectable		 2q2hA-4c3hA:
6.27
2q2hB-4c3hA:
6.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 12 THR A 681
SER A 784
ASN A 767
VAL A 769
GLY A 779
 None
 1.21A 2x2iC-4c3hA:
undetectable		 2x2iC-4c3hA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 10 THR A 681
SER A 784
ASN A 767
VAL A 769
GLY A 779
 None
 1.22A 2x2iD-4c3hA:
undetectable		 2x2iD-4c3hA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 THR A 594
THR A 653
HIS A 603
LEU A 616
 None
 1.18A 2zj0A-4c3hA:
undetectable		 2zj0A-4c3hA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA43
(Saccharomyces
cerevisiae) 		4 / 8 HIS G 144
ILE G 162
TRP G 217
PHE G 168
 None
 1.33A 3ccfB-4c3hG:
undetectable		 3ccfB-4c3hG:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 THR A 594
THR A 653
HIS A 603
LEU A 616
 None
 1.26A 3ce6A-4c3hA:
undetectable		 3ce6A-4c3hA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 THR A 594
THR A 653
HIS A 603
LEU A 616
 None
 1.25A 3ce6C-4c3hA:
undetectable		 3ce6C-4c3hA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 478
ASP A 585
GLU A 518
GLU A 509
 None
 1.30A 3dh0B-4c3hA:
undetectable		 3dh0B-4c3hA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA12
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 5 PRO I  38
VAL I  28
THR A1275
GLY A1277
 None
 1.09A 3elzB-4c3hI:
undetectable		 3elzB-4c3hI:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 7 HIS A1581
ILE A1179
VAL A1032
GLN A1047
 None
 0.91A 3fi0E-4c3hA:
undetectable		 3fi0E-4c3hA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 801
LEU A 736
SER A 789
VAL A 809
ILE A 732
 None
 1.23A 3frqA-4c3hA:
undetectable		 3frqA-4c3hA:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 859
LEU A 892
LEU A 864
GLY A 854
GLU A 856
 None
 1.07A 3g2oB-4c3hA:
undetectable		 3g2oB-4c3hA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 ASN A 748
MET A1170
PHE A1068
 None
 1.09A 3g4lD-4c3hA:
undetectable		 3g4lD-4c3hA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 ARG A1295
ASP A1298
ASP A1268
 None
 0.86A 3jayA-4c3hA:
undetectable		 3jayA-4c3hA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 ARG A1295
ASP A1298
ASP A1268
 None
 0.74A 3jb2A-4c3hA:
undetectable		 3jb2A-4c3hA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 ARG A1295
ASP A1298
ASP A1268
 None
 0.81A 3jb3A-4c3hA:
undetectable		 3jb3A-4c3hA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 438
VAL A 456
LEU A 460
LEU A1622
 None
 0.62A 3kp6A-4c3hA:
undetectable
3kp6B-4c3hA:
undetectable		 3kp6A-4c3hA:
6.93
3kp6B-4c3hA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA43
(Saccharomyces
cerevisiae) 		4 / 8 ILE G 107
PRO G 112
SER G  48
PRO G  51
 None
 0.95A 3lslA-4c3hG:
undetectable
3lslD-4c3hG:
undetectable		 3lslA-4c3hG:
19.46
3lslD-4c3hG:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA43
(Saccharomyces
cerevisiae) 		4 / 8 PRO G  51
ILE G 107
PRO G 112
SER G  48
 None
 0.91A 3lslA-4c3hG:
undetectable
3lslD-4c3hG:
undetectable		 3lslA-4c3hG:
19.46
3lslD-4c3hG:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 11 THR A1561
SER A1543
THR A1542
ALA A1558
ALA A1548
 None
 1.14A 3mg0H-4c3hA:
undetectable
3mg0I-4c3hA:
undetectable		 3mg0H-4c3hA:
9.77
3mg0I-4c3hA:
8.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 PHE A 223
GLN A 126
PHE A 108
 None
 0.78A 3rv5A-4c3hA:
undetectable		 3rv5A-4c3hA:
4.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 12 GLY A1593
GLY A1554
ALA A1558
ALA A1547
ALA A1548
 None
 1.03A 3sudD-4c3hA:
undetectable		 3sudD-4c3hA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA12
(Saccharomyces
cerevisiae) 		3 / 3 THR I 115
ASN I  95
GLU I  93
 None
 0.71A 3v4tA-4c3hI:
undetectable
3v4tC-4c3hI:
undetectable		 3v4tA-4c3hI:
16.26
3v4tC-4c3hI:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 658
ARG A 667
GLY A 792
SER A 789
 None
 0.89A 4cp3A-4c3hA:
undetectable
4cp3B-4c3hA:
undetectable		 4cp3A-4c3hA:
5.77
4cp3B-4c3hA:
5.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 9 LYS A 330
HIS A 107
ILE A 275
MET A 274
 None
 1.24A 4jvlA-4c3hA:
undetectable		 4jvlA-4c3hA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 LYS A 877
LEU A 875
GLU A 874
LEU A 864
 None
 1.32A 4k4yA-4c3hA:
undetectable		 4k4yA-4c3hA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 LYS A 877
LEU A 875
GLU A 874
LEU A 864
 None
 1.32A 4k4yI-4c3hA:
undetectable		 4k4yI-4c3hA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 THR A 594
THR A 653
HIS A 603
LEU A 616
 None
 1.23A 4lvcA-4c3hA:
undetectable		 4lvcA-4c3hA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 THR A 594
THR A 653
HIS A 603
LEU A 616
 None
 1.23A 4lvcC-4c3hA:
undetectable		 4lvcC-4c3hA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA43
(Saccharomyces
cerevisiae) 		4 / 5 GLY G 146
SER G 156
ALA G 155
PHE G 138
 None
 0.91A 4m93B-4c3hG:
undetectable
4m93C-4c3hG:
undetectable		 4m93B-4c3hG:
18.67
4m93C-4c3hG:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 ILE A 130
LEU A 125
ASP A 137
GLU A 132
 None
 0.98A 4nkxB-4c3hA:
undetectable		 4nkxB-4c3hA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 918
ASN A 840
ASP A 832
 None
 0.80A 4o1eA-4c3hA:
undetectable		 4o1eA-4c3hA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 794
PHE A 771
LEU A 776
VAL A 809
LEU A 813
 None
 1.39A 4po0A-4c3hA:
3.5		 4po0A-4c3hA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 11 THR A1561
SER A1543
THR A1542
ALA A1558
ALA A1548
 None
 1.15A 4qvvH-4c3hA:
undetectable		 4qvvH-4c3hA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 11 THR A1561
SER A1543
THR A1542
ALA A1558
ALA A1548
 None
 1.15A 4qvvV-4c3hA:
undetectable		 4qvvV-4c3hA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 990
GLY A 948
THR A 904
LEU A 847
 None
 0.94A 4zdzA-4c3hA:
undetectable		 4zdzA-4c3hA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 SER A 811
ARG A 615
GLY A 496
GLU A 611
 None
 1.12A 5cdqA-4c3hA:
5.4
5cdqB-4c3hA:
undetectable
5cdqC-4c3hA:
5.4		 5cdqA-4c3hA:
14.69
5cdqB-4c3hA:
8.35
5cdqC-4c3hA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 SER A 811
ARG A 615
GLY A 496
GLU A 611
 None
 1.12A 5cdqR-4c3hA:
5.1
5cdqS-4c3hA:
undetectable
5cdqT-4c3hA:
4.4		 5cdqR-4c3hA:
14.69
5cdqS-4c3hA:
8.35
5cdqT-4c3hA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 12 THR A1561
SER A1543
THR A1542
ALA A1558
ALA A1548
 None
 1.16A 5d0xH-4c3hA:
undetectable
5d0xI-4c3hA:
undetectable		 5d0xH-4c3hA:
9.80
5d0xI-4c3hA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 793
ALA A 806
VAL A 809
HIS A 798
 None
 0.83A 5eclD-4c3hA:
0.7		 5eclD-4c3hA:
16.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 990
GLY A 948
THR A 904
LEU A 847
 None
 0.93A 5esfA-4c3hA:
undetectable		 5esfA-4c3hA:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA12
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 ARG I 122
ASN I 124
ASP A 627
 None
 0.84A 5gwxA-4c3hI:
undetectable		 5gwxA-4c3hI:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA43
(Saccharomyces
cerevisiae) 		4 / 4 THR G  34
LEU G 133
HIS G 150
GLY G 135
 None
 1.41A 5gwyA-4c3hG:
undetectable		 5gwyA-4c3hG:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA43
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 MET G  52
HIS A 571
GLY G  60
 None
 0.59A 5gwzB-4c3hG:
undetectable		 5gwzB-4c3hG:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 ILE A1501
PRO A1502
ILE A1504
 None
 0.27A 5hw8F-4c3hA:
undetectable		 5hw8F-4c3hA:
5.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 912
GLN A 942
CYH A 945
 None
 0.47A 5icxA-4c3hA:
3.7
5icxE-4c3hA:
undetectable		 5icxA-4c3hA:
8.53
5icxE-4c3hA:
1.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 912
GLN A 942
CYH A 945
 None
 0.63A 5icxC-4c3hA:
3.7
5icxF-4c3hA:
undetectable		 5icxC-4c3hA:
8.53
5icxF-4c3hA:
1.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 11 ASN A 493
VAL A 812
SER A 811
THR A 492
GLU A 491
 None
 1.46A 5jh7B-4c3hA:
undetectable		 5jh7B-4c3hA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 9 ASN A1648
ASP A1040
ILE A1038
GLY A1186
ILE A1187
 None
 0.99A 5kr2C-4c3hA:
undetectable		 5kr2C-4c3hA:
4.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 12 THR A1561
SER A1543
THR A1542
ALA A1558
ALA A1548
 None
 1.11A 5l5zH-4c3hA:
undetectable
5l5zI-4c3hA:
undetectable		 5l5zH-4c3hA:
9.80
5l5zI-4c3hA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 12 THR A1561
SER A1543
THR A1542
ALA A1558
ALA A1548
 None
 1.11A 5l5zV-4c3hA:
undetectable
5l5zW-4c3hA:
undetectable		 5l5zV-4c3hA:
9.80
5l5zW-4c3hA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 THR A 318
PRO A  84
ASP A 358
 None
 0.88A 5l8dB-4c3hA:
undetectable		 5l8dB-4c3hA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 THR A 318
PRO A  84
ASP A 358
 None
 0.88A 5mwuB-4c3hA:
undetectable		 5mwuB-4c3hA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 576
LYS A   5
SER A   4
 None
 1.18A 5odiA-4c3hA:
undetectable		 5odiA-4c3hA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 584
ASN A 515
GLU A 509
ARG A 579
 None
 0.92A 6b8kA-4c3hA:
undetectable		 6b8kA-4c3hA:
3.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		5 / 12 LEU A1217
ASP A1390
ILE A1225
SER A1230
ILE A1233
 None
 0.98A 6ecxA-4c3hA:
undetectable		 6ecxA-4c3hA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 THR A 594
THR A 653
HIS A 603
LEU A 616
 None
 1.23A 6gbnA-4c3hA:
undetectable		 6gbnA-4c3hA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 THR A 594
THR A 653
HIS A 603
LEU A 616
 None
 1.22A 6gbnD-4c3hA:
undetectable		 6gbnD-4c3hA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 5 GLY A 663
LEU A 658
SER A1061
TYR A 791
 None
 1.30A 6ji6A-4c3hA:
undetectable		 6ji6A-4c3hA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 8 ALA A1168
GLY A1134
LEU A1133
GLU A1092
 None
 0.78A 6mdqA-4c3hA:
2.7		 6mdqA-4c3hA:
3.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 617
ASP A 631
TYR A 624
HIS A 673
 None
 1.40A 6nknA-4c3hA:
undetectable
6nknC-4c3hA:
undetectable		 6nknA-4c3hA:
14.30
6nknC-4c3hA:
9.38