SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c41'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
4 / 8 SER A  44
SER A 341
ALA A 327
ILE A 160
None
1.16A 1gm7A-4c41A:
undetectable
1gm7B-4c41A:
undetectable
1gm7A-4c41A:
20.49
1gm7B-4c41A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
4 / 8 SER A  44
SER A 341
ALA A 327
ILE A 160
None
1.20A 1pnlA-4c41A:
undetectable
1pnlB-4c41A:
undetectable
1pnlA-4c41A:
20.49
1pnlB-4c41A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 10 LEU A 245
VAL A 254
ILE A 255
TYR A  29
ILE A  41
None
1.30A 1q6iB-4c41A:
undetectable
1q6iB-4c41A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
4 / 5 GLY A 106
ILE A 179
VAL A 176
SER A  47
None
1.19A 1rs7A-4c41A:
undetectable
1rs7A-4c41A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 LEU A  68
LEU A  67
VAL A 344
HIS A  84
ILE A  83
None
1.03A 1s9pA-4c41A:
undetectable
1s9pA-4c41A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 LEU A  68
LEU A  67
VAL A 344
HIS A  84
ILE A  83
None
1.13A 1s9pD-4c41A:
undetectable
1s9pD-4c41A:
21.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
8 / 12 ALA A  18
VAL A  22
GLN A 232
THR A 240
PHE A 242
ARG A 260
ILE A 263
PHE A 366
None
1.04A 2v95A-4c41A:
39.4
2v95A-4c41A:
61.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 GLN A 232
PHE A 242
ASN A 264
SER A 267
HIS A 368
None
1.17A 2vdyA-4c41A:
56.7
2vdyA-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 GLN A 232
THR A 240
PHE A 242
ASN A 264
SER A 267
None
0.85A 2vdyA-4c41A:
56.7
2vdyA-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 SER A  19
VAL A  22
GLN A 232
ARG A 260
PHE A 366
None
1.10A 2vdyA-4c41A:
56.7
2vdyA-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
7 / 12 VAL A  22
GLN A 232
PHE A 242
ILE A 263
ASN A 264
PHE A 366
HIS A 368
None
0.96A 2vdyA-4c41A:
56.7
2vdyA-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
7 / 12 VAL A  22
GLN A 232
THR A 240
PHE A 242
ARG A 260
ILE A 263
PHE A 366
None
1.13A 2vdyA-4c41A:
56.7
2vdyA-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
7 / 12 VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
None
0.67A 2vdyA-4c41A:
56.7
2vdyA-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
7 / 12 SER A  19
VAL A  22
GLN A 232
PHE A 242
ARG A 260
ILE A 263
PHE A 366
None
1.04A 2vdyB-4c41A:
57.2
2vdyB-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
8 / 12 VAL A  22
GLN A 232
THR A 240
PHE A 242
ARG A 260
ILE A 263
SER A 267
PHE A 366
None
0.98A 2vdyB-4c41A:
57.2
2vdyB-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
8 / 12 VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
HIS A 368
None
0.83A 2vdyB-4c41A:
57.2
2vdyB-4c41A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
8 / 12 VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
SER A 267
PHE A 366
None
0.63A 2vdyB-4c41A:
57.2
2vdyB-4c41A:
96.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 PHE A  24
MET A 297
LEU A  32
ILE A  43
HIS A 325
None
1.37A 2ydoA-4c41A:
undetectable
2ydoA-4c41A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
4 / 8 THR A 338
LEU A 329
HIS A 325
ASN A 177
None
1.15A 3kp2A-4c41A:
undetectable
3kp2B-4c41A:
undetectable
3kp2A-4c41A:
17.44
3kp2B-4c41A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 PHE A 366
PHE A  94
THR A 370
PHE A  26
ILE A 362
None
1.17A 3nxuB-4c41A:
undetectable
3nxuB-4c41A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
4 / 6 PHE A  87
ASN A  21
PHE A  24
ALA A  25
None
1.02A 3t3sB-4c41A:
undetectable
3t3sB-4c41A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
4 / 6 SER A  56
HIS A  62
THR A  59
ARG A 311
None
1.48A 3thrB-4c41A:
undetectable
3thrB-4c41A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
4 / 7 SER A 267
VAL A  22
ILE A 263
TYR A 235
None
1.03A 3tneB-4c41A:
undetectable
3tneB-4c41A:
22.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BB2_B_STRB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
6 / 11 ALA A  18
GLN A 232
THR A 240
PHE A 242
ARG A 260
ILE A 263
None
1.11A 4bb2A-4c41A:
48.5
4bb2B-4c41A:
undetectable
4bb2A-4c41A:
93.33
4bb2B-4c41A:
9.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BB2_B_STRB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
8 / 11 ALA A  18
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
SER A 267
HIS A 368
None
0.86A 4bb2A-4c41A:
48.5
4bb2B-4c41A:
undetectable
4bb2A-4c41A:
93.33
4bb2B-4c41A:
9.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 ALA A  18
SER A  19
VAL A  22
GLN A 232
PHE A 366
None
0.74A 4c49A-4c41A:
58.9
4c49A-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
7 / 12 ALA A  18
VAL A  22
GLN A 232
PHE A 242
ILE A 263
PHE A 366
HIS A 368
None
1.01A 4c49A-4c41A:
58.9
4c49A-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
8 / 12 ALA A  18
VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
None
0.70A 4c49A-4c41A:
58.9
4c49A-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 GLN A 232
THR A 240
PHE A 242
ASN A 264
SER A 267
None
0.96A 4c49A-4c41A:
58.9
4c49A-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 GLN A 232
THR A 240
PHE A 242
ASN A 264
SER A 267
None
0.90A 4c49B-4c41A:
58.8
4c49B-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 SER A  19
VAL A  22
GLN A 232
PHE A 242
PHE A 366
None
0.72A 4c49B-4c41A:
58.8
4c49B-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
6 / 12 VAL A  22
GLN A 232
PHE A 242
ILE A 263
PHE A 366
HIS A 368
None
1.11A 4c49B-4c41A:
58.8
4c49B-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
7 / 12 VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
None
0.72A 4c49B-4c41A:
58.8
4c49B-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 GLN A 232
THR A 240
PHE A 242
ASN A 264
SER A 267
None
0.84A 4c49C-4c41A:
58.2
4c49C-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 THR A 240
PHE A 242
ASN A 264
SER A 267
HIS A 368
None
1.03A 4c49C-4c41A:
58.2
4c49C-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
7 / 12 VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
None
0.67A 4c49C-4c41A:
58.2
4c49C-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
6 / 12 VAL A  22
THR A 240
PHE A 242
ASN A 264
PHE A 366
HIS A 368
None
0.82A 4c49C-4c41A:
58.2
4c49C-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
6 / 12 GLN A 232
THR A 240
PHE A 242
ASN A 264
SER A 267
PHE A 366
None
0.69A 4c49D-4c41A:
56.3
4c49D-4c41A:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
7 / 12 VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
None
0.71A 4c49D-4c41A:
56.3
4c49D-4c41A:
99.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
4 / 7 LEU A 346
SER A 114
VAL A 133
MET A 136
None
1.25A 4klrA-4c41A:
undetectable
4klrA-4c41A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
3 / 3 LYS A  39
ILE A  41
ILE A  43
None
0.56A 4y0qA-4c41A:
undetectable
4y0qA-4c41A:
18.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HGC_A_HCYA501_1
(SERPIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 12 THR A 240
PHE A 242
ILE A 263
SER A 267
PHE A 366
None
0.80A 5hgcA-4c41A:
45.2
5hgcA-4c41A:
41.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
3 / 3 SER A  56
HIS A  84
TYR A 129
None
0.97A 5y2tA-4c41A:
undetectable
5y2tA-4c41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
3 / 3 LYS A 319
ASN A 347
SER A 169
None
1.30A 5yw0A-4c41A:
undetectable
5yw0A-4c41A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9H_R_ADNR400_1
(CHIMERA PROTEIN OF
MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4 AND
ADENOSINE RECEPTOR
A1)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo
sapiens)
5 / 10 PHE A  24
MET A 297
LEU A  32
ILE A  43
HIS A 325
None
1.26A 6d9hR-4c41A:
undetectable
6d9hR-4c41A:
12.63