SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c45'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 4c45 PTERIN-4-ALPHA-CARBI
NOLAMINE DEHYDRATASE
2
(Homo
sapiens) 		4 / 6 ASP A  33
ILE A  35
GLU A  31
ARG A  14
 None
 1.08A 1mt1A-4c45A:
undetectable
1mt1F-4c45A:
undetectable		 1mt1A-4c45A:
17.65
1mt1F-4c45A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 4c45 PTERIN-4-ALPHA-CARBI
NOLAMINE DEHYDRATASE
2
(Homo
sapiens) 		4 / 8 LYS A  92
VAL A  91
THR A  79
LEU A   9
 None
 1.04A 1z2bB-4c45A:
undetectable		 1z2bB-4c45A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEK_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 4c45 PTERIN-4-ALPHA-CARBI
NOLAMINE DEHYDRATASE
2
(Homo
sapiens) 		5 / 12 GLY A  49
ASN A  69
ASN A  45
HIS A  42
TYR A  71
 None
 1.49A 3mekA-4c45A:
undetectable		 3mekA-4c45A:
11.42