SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 4c47 INNER MEMBRANE
LIPOPROTEIN
(Salmonella
enterica) 		4 / 8 PHE A 145
MET A 172
THR A 184
LEU A 178
 None
 1.27A 1ea1A-4c47A:
undetectable		 1ea1A-4c47A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 4c47 INNER MEMBRANE
LIPOPROTEIN
(Salmonella
enterica) 		4 / 8 TYR A  92
TYR A 200
LEU A 160
TRP A 163
 None
 1.23A 3uzzB-4c47A:
undetectable		 3uzzB-4c47A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CUT_A_TYLA2971_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 4c47 INNER MEMBRANE
LIPOPROTEIN
(Salmonella
enterica) 		4 / 4 VAL A 210
VAL A 140
ASN A 107
ILE A 205
 None
 1.08A 4cutA-4c47A:
undetectable		 4cutA-4c47A:
17.07