SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c4b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 6 TRP A   9
HIS A  14
GLY A  35
TRP A 116
 None
FE2  A1001 (-3.4A)
None
None
 1.48A 1mxdA-4c4bA:
undetectable		 1mxdA-4c4bA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  14
HIS A 113
HIS A  46
HIS A  40
 FE2  A1001 (-3.4A)
FE2  A1001 (-3.2A)
FE2  A1001 (-3.4A)
FE2  A1001 (-3.4A)
 1.37A 2fqgA-4c4bA:
undetectable		 2fqgA-4c4bA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 6 ASP A   8
HIS A  40
HIS A  14
HIS A 113
 None
FE2  A1001 (-3.4A)
FE2  A1001 (-3.4A)
FE2  A1001 (-3.2A)
 1.01A 3c0zC-4c4bA:
undetectable		 3c0zC-4c4bA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA504_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.16A 5mejA-4c4bA:
undetectable		 5mejA-4c4bA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA504_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.18A 5mewA-4c4bA:
undetectable		 5mewA-4c4bA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA504_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.19A 5mhuA-4c4bA:
undetectable		 5mhuA-4c4bA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA504_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.20A 5mhvA-4c4bA:
undetectable		 5mhvA-4c4bA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA604_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.20A 5mhwA-4c4bA:
undetectable		 5mhwA-4c4bA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA604_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.19A 5mhxA-4c4bA:
undetectable		 5mhxA-4c4bA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA604_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.20A 5mhyA-4c4bA:
undetectable		 5mhyA-4c4bA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA604_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.20A 5mhzA-4c4bA:
undetectable		 5mhzA-4c4bA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA604_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.20A 5mi1A-4c4bA:
undetectable		 5mi1A-4c4bA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA604_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.20A 5mi2A-4c4bA:
undetectable		 5mi2A-4c4bA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA604_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.20A 5miaA-4c4bA:
undetectable		 5miaA-4c4bA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA604_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.20A 5mibA-4c4bA:
undetectable		 5mibA-4c4bA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA604_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.20A 5micA-4c4bA:
undetectable		 5micA-4c4bA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA604_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.21A 5midA-4c4bA:
undetectable		 5midA-4c4bA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA604_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.20A 5mieA-4c4bA:
undetectable		 5mieA-4c4bA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA604_0
(LACCASE 2)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  46
CYH A 110
ILE A 112
HIS A 113
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
None
FE2  A1001 (-3.2A)
 1.21A 5migA-4c4bA:
undetectable		 5migA-4c4bA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A  14
CYH A 110
HIS A  46
HIS A  40
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
FE2  A1001 (-3.4A)
FE2  A1001 (-3.4A)
 1.23A 5zrdA-4c4bA:
1.9		 5zrdA-4c4bA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A 113
CYH A 110
HIS A  46
HIS A  14
 FE2  A1001 (-3.2A)
FE2  A1001 (-2.4A)
FE2  A1001 (-3.4A)
FE2  A1001 (-3.4A)
 1.48A 5zrdA-4c4bA:
1.9		 5zrdA-4c4bA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 4 HIS A 113
CYH A 110
HIS A  46
HIS A  40
 FE2  A1001 (-3.2A)
FE2  A1001 (-2.4A)
FE2  A1001 (-3.4A)
FE2  A1001 (-3.4A)
 1.24A 5zrdA-4c4bA:
1.9		 5zrdA-4c4bA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 5 HIS A 113
CYH A 110
HIS A  46
HIS A  40
 FE2  A1001 (-3.2A)
FE2  A1001 (-2.4A)
FE2  A1001 (-3.4A)
FE2  A1001 (-3.4A)
 1.17A 5zrdB-4c4bA:
undetectable		 5zrdB-4c4bA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 5 HIS A  14
CYH A 110
HIS A  46
HIS A  40
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
FE2  A1001 (-3.4A)
FE2  A1001 (-3.4A)
 1.27A 5zrdC-4c4bA:
3.4		 5zrdC-4c4bA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 5 HIS A 113
CYH A 110
HIS A  46
HIS A  40
 FE2  A1001 (-3.2A)
FE2  A1001 (-2.4A)
FE2  A1001 (-3.4A)
FE2  A1001 (-3.4A)
 1.26A 5zrdC-4c4bA:
3.4		 5zrdC-4c4bA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 5 HIS A  14
CYH A 110
HIS A  46
HIS A  40
 FE2  A1001 (-3.4A)
FE2  A1001 (-2.4A)
FE2  A1001 (-3.4A)
FE2  A1001 (-3.4A)
 1.21A 5zrdD-4c4bA:
3.3		 5zrdD-4c4bA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4c4b SUPEROXIDE REDUCTASE
(Archaeoglobus
fulgidus) 		4 / 5 HIS A 113
CYH A 110
HIS A  46
HIS A  40
 FE2  A1001 (-3.2A)
FE2  A1001 (-2.4A)
FE2  A1001 (-3.4A)
FE2  A1001 (-3.4A)
 1.18A 5zrdD-4c4bA:
3.3		 5zrdD-4c4bA:
13.08