SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		6 / 8 HIS A 270
GLY A 273
LYS A 274
THR A 275
LEU A 378
ASP A 381
 HEM  A1741 (-3.4A)
HEM  A1741 (-3.4A)
None
HEM  A1741 (-3.8A)
None
None
 0.34A 1aegA-4c51A:
32.0		 1aegA-4c51A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 7 LYS A 613
LEU A 617
LEU A 619
VAL A 694
 None
 0.87A 1dvxB-4c51A:
undetectable		 1dvxB-4c51A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 0.97A 1gfzA-4c51A:
undetectable		 1gfzA-4c51A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 GLU A 454
GLN A 525
LYS A 537
VAL A 450
 None
GLC  A1742 (-3.4A)
None
None
 1.45A 1l2iB-4c51A:
undetectable		 1l2iB-4c51A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 1.01A 1l5qA-4c51A:
undetectable		 1l5qA-4c51A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 0.99A 1l7xA-4c51A:
undetectable		 1l7xA-4c51A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 1.02A 1l7xB-4c51A:
undetectable		 1l7xB-4c51A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 122
ALA A 109
LEU A 415
ILE A 103
LEU A 173
 None
None
None
HEM  A1741 ( 3.9A)
None
 1.06A 1rg7A-4c51A:
undetectable		 1rg7A-4c51A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 LYS A 613
LEU A 617
LEU A 619
SER A 620
 None
 0.95A 1tz8C-4c51A:
undetectable
1tz8D-4c51A:
undetectable		 1tz8C-4c51A:
11.11
1tz8D-4c51A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_D_DESD128_1
(TRANSTHYRETIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 4 LYS A 613
LEU A 617
LEU A 619
SER A 620
 None
 1.35A 1tz8D-4c51A:
undetectable		 1tz8D-4c51A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 521
LEU A 467
GLY A 548
ALA A 476
ALA A 480
 None
 0.93A 2bm9A-4c51A:
undetectable		 2bm9A-4c51A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 521
LEU A 467
GLY A 548
ALA A 476
ALA A 480
 None
 0.86A 2bm9C-4c51A:
undetectable		 2bm9C-4c51A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 521
LEU A 467
GLY A 548
ALA A 476
ALA A 480
 None
 0.92A 2bm9D-4c51A:
undetectable		 2bm9D-4c51A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 521
LEU A 467
GLY A 548
ALA A 476
ALA A 480
 None
 0.99A 2bm9E-4c51A:
undetectable		 2bm9E-4c51A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 521
LEU A 467
GLY A 548
ALA A 476
ALA A 480
 None
 1.04A 2bm9F-4c51A:
undetectable		 2bm9F-4c51A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 521
LEU A 467
GLY A 548
ALA A 476
ALA A 480
 None
 0.92A 2br4A-4c51A:
undetectable		 2br4A-4c51A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 521
LEU A 467
GLY A 548
ALA A 476
ALA A 480
 None
 0.88A 2br4C-4c51A:
undetectable		 2br4C-4c51A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 521
LEU A 467
GLY A 548
ALA A 476
ALA A 480
 None
 0.92A 2br4D-4c51A:
undetectable		 2br4D-4c51A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 521
LEU A 467
GLY A 548
ALA A 476
ALA A 480
 None
 0.91A 2br4E-4c51A:
undetectable		 2br4E-4c51A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 521
LEU A 467
GLY A 548
ALA A 476
ALA A 480
 None
 1.03A 2br4F-4c51A:
undetectable		 2br4F-4c51A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 10 TYR A 390
GLU A 407
THR A 262
ALA A 263
ALA A 264
 None
 1.12A 2ej3B-4c51A:
undetectable		 2ej3B-4c51A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 573
GLY A 495
GLY A 570
VAL A 739
ASP A 738
 GLC  A1742 (-3.5A)
None
None
None
None
 1.31A 2fqyA-4c51A:
undetectable		 2fqyA-4c51A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 ASP A 117
ARG A 119
ASP A 194
ASP A 612
 None
 1.05A 2j2pE-4c51A:
undetectable
2j2pF-4c51A:
undetectable		 2j2pE-4c51A:
15.72
2j2pF-4c51A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMQ_A_BEZA3_0
(PROTEIN NDRG2)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 7 TYR A 413
TYR A 426
PHE A 183
HIS A 417
 None
 1.10A 2qmqA-4c51A:
undetectable		 2qmqA-4c51A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X08_A_ASCA1253_0
(CYTOCHROME C
PEROXIDASE,
MITOCHONDRIAL)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 9 ALA A  93
ASP A  94
TYR A  98
PRO A 100
HIS A 276
 None
HEM  A1741 ( 4.9A)
None
HEM  A1741 (-4.7A)
HEM  A1741 (-3.9A)
 0.75A 2x08A-4c51A:
31.9		 2x08A-4c51A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 8 LEU A 458
ILE A 524
ARG A 463
GLY A 466
 None
 0.94A 3b9lA-4c51A:
2.3		 3b9lA-4c51A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 5 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 1.01A 3bcrA-4c51A:
undetectable		 3bcrA-4c51A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 7 VAL A 544
VAL A 545
GLY A 547
ARG A 571
 None
 0.66A 3bjwC-4c51A:
undetectable		 3bjwC-4c51A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 7 VAL A 544
VAL A 545
GLY A 548
ARG A 571
 None
 0.88A 3bjwC-4c51A:
undetectable		 3bjwC-4c51A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 8 VAL A 544
VAL A 545
GLY A 547
ARG A 571
 None
 0.60A 3bjwA-4c51A:
undetectable		 3bjwA-4c51A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 8 VAL A 544
VAL A 545
GLY A 548
ARG A 571
 None
 0.83A 3bjwA-4c51A:
undetectable		 3bjwA-4c51A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		3 / 3 GLY A 125
ASP A 189
SER A 160
 None
 0.63A 3brfA-4c51A:
undetectable		 3brfA-4c51A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 1.02A 3dd1A-4c51A:
undetectable		 3dd1A-4c51A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 0.96A 3dd1B-4c51A:
undetectable		 3dd1B-4c51A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 1.00A 3ddsA-4c51A:
undetectable		 3ddsA-4c51A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 0.99A 3ddsB-4c51A:
undetectable		 3ddsB-4c51A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 0.98A 3ddwA-4c51A:
undetectable		 3ddwA-4c51A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 1.00A 3ddwB-4c51A:
undetectable		 3ddwB-4c51A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 4 GLN A 500
PRO A 501
VAL A 581
GLU A 582
 None
 1.32A 3huoA-4c51A:
undetectable		 3huoA-4c51A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 121
ALA A 222
ASP A 117
GLY A 199
ARG A 209
 None
 1.31A 3jzjA-4c51A:
undetectable		 3jzjA-4c51A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 595
THR A 647
THR A 468
 None
 0.64A 3k2hB-4c51A:
undetectable		 3k2hB-4c51A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 4 GLY A 121
TYR A 113
GLY A 118
ASP A 487
 None
 1.13A 3kl3A-4c51A:
undetectable		 3kl3A-4c51A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 7 GLY A 691
PHE A 724
PHE A 720
PHE A 658
 None
 1.15A 3ko0L-4c51A:
undetectable
3ko0N-4c51A:
undetectable		 3ko0L-4c51A:
9.18
3ko0N-4c51A:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 548
THR A 475
ARG A 498
LEU A 543
LEU A 472
 None
None
GLC  A1742 ( 4.3A)
None
None
 1.30A 3ndvA-4c51A:
undetectable
3ndvB-4c51A:
undetectable		 3ndvA-4c51A:
20.30
3ndvB-4c51A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 472
GLY A 548
THR A 475
ARG A 498
LEU A 543
 None
None
None
GLC  A1742 ( 4.3A)
None
 1.29A 3ndvC-4c51A:
undetectable
3ndvD-4c51A:
undetectable		 3ndvC-4c51A:
20.30
3ndvD-4c51A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 11 VAL A 517
LEU A 521
LEU A 514
GLY A 548
ALA A 476
 None
 1.20A 3pghB-4c51A:
undetectable		 3pghB-4c51A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 4 ASP A 511
ASP A 509
GLY A 504
THR A 475
 None
 1.19A 3tl9B-4c51A:
undetectable		 3tl9B-4c51A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		3 / 3 THR A 579
VAL A 581
GLU A 577
 None
 0.63A 3v4tA-4c51A:
undetectable
3v4tD-4c51A:
undetectable		 3v4tA-4c51A:
21.60
3v4tD-4c51A:
21.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 8 TRP A  90
TRP A  91
LYS A 143
LEU A 298
GLY A 307
 None
 0.40A 3wxoA-4c51A:
61.5		 3wxoA-4c51A:
54.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		3 / 3 TYR A 678
ARG A 693
SER A 692
 None
 1.15A 4dr2I-4c51A:
undetectable
4dr2J-4c51A:
undetectable		 4dr2I-4c51A:
10.95
4dr2J-4c51A:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 616
ASN A 615
LEU A 617
ALA A 614
ALA A 591
 None
 1.05A 4fn9A-4c51A:
undetectable		 4fn9A-4c51A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 473
ALA A 556
PHE A 724
MET A 732
LEU A 617
 None
 1.40A 4iarA-4c51A:
undetectable		 4iarA-4c51A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 PRO A 432
TYR A 426
GLY A 184
ILE A 416
PHE A 181
 None
 0.91A 4kosA-4c51A:
undetectable		 4kosA-4c51A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 PRO A 432
TYR A 426
GLY A 184
ILE A 416
PHE A 181
 None
 0.88A 4kotA-4c51A:
undetectable		 4kotA-4c51A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 PRO A 432
TYR A 426
GLY A 184
ILE A 416
PHE A 181
 None
 1.01A 4kovA-4c51A:
undetectable		 4kovA-4c51A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 ILE A 103
ILE A 416
PHE A 408
LEU A 265
 HEM  A1741 ( 3.9A)
None
None
HEM  A1741 (-4.2A)
 0.93A 4m51A-4c51A:
undetectable		 4m51A-4c51A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 7 TYR A 197
GLU A 217
GLU A 208
GLU A 201
 None
 1.11A 4mi4A-4c51A:
undetectable
4mi4C-4c51A:
undetectable		 4mi4A-4c51A:
13.96
4mi4C-4c51A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 735
VAL A 545
ALA A 476
SER A 481
ASP A 542
 None
 1.21A 4mm8A-4c51A:
undetectable		 4mm8A-4c51A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NSB_A_AINA402_1
(CHITINASE-3-LIKE
PROTEIN 1)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 7 THR A 314
ARG A 104
TRP A  91
LEU A 101
 HEM  A1741 (-3.5A)
HEM  A1741 (-4.0A)
None
HEM  A1741 ( 3.9A)
 1.27A 4nsbA-4c51A:
undetectable		 4nsbA-4c51A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 631
GLY A 630
LEU A 653
VAL A 469
THR A 647
 None
 1.14A 4ojbA-4c51A:
undetectable		 4ojbA-4c51A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 631
GLY A 630
LEU A 653
VAL A 469
THR A 647
 None
 1.12A 4okbA-4c51A:
undetectable		 4okbA-4c51A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 631
GLY A 630
LEU A 653
VAL A 469
THR A 647
 None
 1.16A 4okxA-4c51A:
undetectable		 4okxA-4c51A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 631
GLY A 630
LEU A 653
VAL A 469
THR A 647
 None
 1.19A 4olmA-4c51A:
undetectable		 4olmA-4c51A:
15.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 6 ASP A  94
TYR A  98
LEU A 101
HIS A 276
THR A 314
 HEM  A1741 ( 4.9A)
None
HEM  A1741 ( 3.9A)
HEM  A1741 (-3.9A)
HEM  A1741 (-3.5A)
 0.30A 4paeA-4c51A:
60.5		 4paeA-4c51A:
54.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 6 LYS A 613
LEU A 617
LEU A 619
SER A 620
 None
 1.04A 4pwjA-4c51A:
undetectable		 4pwjA-4c51A:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 320
PRO A 325
THR A 326
SER A 175
GLY A 177
 None
 1.25A 4q15A-4c51A:
undetectable		 4q15A-4c51A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 320
PRO A 325
THR A 326
SER A 175
GLY A 177
 None
 1.25A 4q15B-4c51A:
undetectable		 4q15B-4c51A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 320
PRO A 325
THR A 326
SER A 175
GLY A 177
 None
 1.27A 4ydqB-4c51A:
undetectable		 4ydqB-4c51A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 8 SER A 160
TYR A  64
ALA A 110
GLY A 123
 None
 0.73A 5albL-4c51A:
undetectable		 5albL-4c51A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 5 LYS A 613
LEU A 617
LEU A 619
VAL A 694
 None
 0.82A 5cr1A-4c51A:
undetectable		 5cr1A-4c51A:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 11 ASN A 493
VAL A 538
SER A 539
THR A 572
LEU A 458
 None
 1.20A 5jh7B-4c51A:
undetectable		 5jh7B-4c51A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 11 ASN A 493
VAL A 538
SER A 539
THR A 572
LEU A 458
 None
 1.23A 5jh7D-4c51A:
undetectable		 5jh7D-4c51A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 517
LEU A 521
LEU A 514
GLY A 548
ALA A 476
 None
 1.14A 5jvzB-4c51A:
0.8		 5jvzB-4c51A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 8 GLU A 318
PRO A 367
GLY A 309
ASP A  94
 None
None
None
HEM  A1741 ( 4.9A)
 0.95A 5kf8A-4c51A:
undetectable		 5kf8A-4c51A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 8 GLU A 318
PRO A 367
GLY A 309
ASP A  94
 None
None
None
HEM  A1741 ( 4.9A)
 0.98A 5kgpA-4c51A:
undetectable		 5kgpA-4c51A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 8 GLU A 318
PRO A 367
GLY A 309
ASP A  94
 None
None
None
HEM  A1741 ( 4.9A)
 1.00A 5kgpB-4c51A:
undetectable		 5kgpB-4c51A:
18.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KSG_B_NIZB809_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		6 / 9 ARG A 119
VAL A 196
GLY A 485
SER A 486
LEU A 616
THR A 618
 None
 0.27A 5ksgB-4c51A:
66.5		 5ksgB-4c51A:
65.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KSN_A_NIZA809_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		6 / 9 ARG A 119
VAL A 196
GLY A 485
SER A 486
LEU A 616
THR A 618
 None
 0.22A 5ksnA-4c51A:
66.6		 5ksnA-4c51A:
65.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KSN_B_NIZB809_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		6 / 9 ARG A 119
VAL A 196
GLY A 485
SER A 486
LEU A 616
THR A 618
 None
 0.25A 5ksnB-4c51A:
66.5		 5ksnB-4c51A:
65.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KT8_B_NIZB809_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		6 / 9 ARG A 119
VAL A 196
GLY A 485
SER A 486
LEU A 616
THR A 618
 None
 0.22A 5kt8B-4c51A:
66.6		 5kt8B-4c51A:
65.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 8 ARG A 119
VAL A 196
GLY A 485
LEU A 616
THR A 618
 None
 0.24A 5sxqA-4c51A:
66.7		 5sxqA-4c51A:
65.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 8 ARG A 119
VAL A 196
GLY A 485
LEU A 616
THR A 618
 None
 0.27A 5sxqB-4c51A:
66.6		 5sxqB-4c51A:
65.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SXS_B_NIZB806_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		6 / 9 ARG A 119
VAL A 196
GLY A 485
SER A 486
LEU A 616
THR A 618
 None
 0.23A 5sxsB-4c51A:
66.5		 5sxsB-4c51A:
65.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 8 ARG A 119
VAL A 196
GLY A 485
LEU A 616
THR A 618
 None
 0.23A 5sxtA-4c51A:
66.7		 5sxtA-4c51A:
65.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 8 ARG A 119
VAL A 196
GLY A 485
LEU A 616
THR A 618
 None
 0.24A 5sxtB-4c51A:
66.6		 5sxtB-4c51A:
65.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYI_A_NIZA805_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 5 ARG A 104
TRP A 107
HIS A 108
PRO A 232
 HEM  A1741 (-4.0A)
HEM  A1741 (-3.6A)
None
HEM  A1741 ( 4.3A)
 0.36A 5syiA-4c51A:
66.6		 5syiA-4c51A:
65.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYI_B_NIZB805_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		6 / 9 ARG A 119
VAL A 196
GLY A 485
SER A 486
LEU A 616
THR A 618
 None
 0.25A 5syiB-4c51A:
66.6		 5syiB-4c51A:
65.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYI_B_NIZB806_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 5 ARG A 104
TRP A 107
HIS A 108
PRO A 232
SER A 315
 HEM  A1741 (-4.0A)
HEM  A1741 (-3.6A)
None
HEM  A1741 ( 4.3A)
HEM  A1741 (-2.9A)
 0.34A 5syiB-4c51A:
66.6		 5syiB-4c51A:
65.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 8 ARG A 119
VAL A 196
GLY A 485
LEU A 616
THR A 618
 None
 0.25A 5syjA-4c51A:
66.5		 5syjA-4c51A:
65.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		6 / 6 ARG A 104
TRP A 107
HIS A 108
LEU A 227
PRO A 232
SER A 315
 HEM  A1741 (-4.0A)
HEM  A1741 (-3.6A)
None
None
HEM  A1741 ( 4.3A)
HEM  A1741 (-2.9A)
 0.32A 5syjA-4c51A:
66.5		 5syjA-4c51A:
65.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 8 ARG A 119
VAL A 196
GLY A 485
LEU A 616
THR A 618
 None
 0.27A 5syjB-4c51A:
66.2		 5syjB-4c51A:
65.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		6 / 6 ARG A 104
TRP A 107
HIS A 108
LEU A 227
PRO A 232
SER A 315
 HEM  A1741 (-4.0A)
HEM  A1741 (-3.6A)
None
None
HEM  A1741 ( 4.3A)
HEM  A1741 (-2.9A)
 0.33A 5syjB-4c51A:
66.2		 5syjB-4c51A:
65.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 634
LEU A 631
GLY A 630
GLY A 629
VAL A 626
 None
 1.09A 5uc1A-4c51A:
undetectable		 5uc1A-4c51A:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 634
LEU A 631
GLY A 630
GLY A 629
VAL A 626
 None
 1.09A 5uc1B-4c51A:
undetectable		 5uc1B-4c51A:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		4 / 7 VAL A 320
PRO A 365
SER A 331
THR A 322
 None
 1.03A 5vkqA-4c51A:
0.0
5vkqD-4c51A:
undetectable		 5vkqA-4c51A:
18.50
5vkqD-4c51A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 320
PRO A 325
THR A 326
SER A 175
GLY A 177
 None
 1.20A 5xipA-4c51A:
undetectable		 5xipA-4c51A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 11 ASP A 542
SER A 539
VAL A 503
ILE A 497
ILE A 518
 None
 1.34A 5y80A-4c51A:
undetectable		 5y80A-4c51A:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDQ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		6 / 9 ARG A 119
VAL A 196
GLY A 485
SER A 486
LEU A 616
THR A 618
 None
 0.24A 6cdqA-4c51A:
66.3		 6cdqA-4c51A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		6 / 9 ARG A 119
VAL A 196
GLY A 485
SER A 486
LEU A 616
THR A 618
 None
 0.25A 6cdqB-4c51A:
66.2		 6cdqB-4c51A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CFQ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		6 / 9 ARG A 119
VAL A 196
GLY A 485
SER A 486
LEU A 616
THR A 618
 None
 0.24A 6cfqB-4c51A:
66.6		 6cfqB-4c51A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 187
PHE A 102
PHE A 185
 None
 0.87A 6nknC-4c51A:
undetectable
6nknJ-4c51A:
undetectable		 6nknC-4c51A:
17.05
6nknJ-4c51A:
5.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 4c51 CATALASE-PEROXIDASE
(Mycobacterium
tuberculosis) 		5 / 9 ILE A  80
ALA A 168
GLY A 169
LEU A 173
GLY A 184
 None
 1.05A 6nm4B-4c51A:
undetectable		 6nm4B-4c51A:
12.64