SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c53'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)
4c53 PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX

(Guanarito
mammarenavirus)
3 / 3 GLY A 377
TYR A 379
SER A 378
None
0.75A 2xatA-4c53A:
undetectable
2xatA-4c53A:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)
4c53 PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX

(Guanarito
mammarenavirus)
3 / 3 ASN A 307
MET A 400
PHE A 302
NAG  A1407 ( 4.6A)
None
None
1.10A 3g4lD-4c53A:
undetectable
3g4lD-4c53A:
18.90