SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c57'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 4c57 NANOBODY
(Lama
glama) 		4 / 7 ASP C  69
VAL C  71
GLY C  55
ILE C  56
 None
 0.75A 1t7iB-4c57C:
undetectable		 1t7iB-4c57C:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 4c57 NANOBODY
(Lama
glama) 		4 / 8 ASP C  69
VAL C  71
GLY C  55
ILE C  56
 None
 0.77A 3nu9A-4c57C:
undetectable		 3nu9A-4c57C:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4c57 NANOBODY
(Lama
glama) 		4 / 5 TYR C 102
LEU C  89
LEU C  94
ARG C  75
 None
 1.26A 4em2A-4c57C:
undetectable		 4em2A-4c57C:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 4c57 NANOBODY
(Lama
glama) 		4 / 6 VAL C  42
SER C 119
ALA C  25
PHE C  30
 None
 1.14A 4nedA-4c57C:
undetectable		 4nedA-4c57C:
16.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 4c57 NANOBODY
(Lama
glama) 		3 / 3 TYR C  67
GLY C  74
THR C  77
 None
 0.18A 6cjkB-4c57C:
17.0		 6cjkB-4c57C:
35.22