SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c60'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 5 HIS A 111
HIS A 287
HIS A 307
ASP A 378
 None
 0.71A 1e9yB-4c60A:
17.2		 1e9yB-4c60A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 6 HIS A 111
HIS A 191
HIS A 287
HIS A 307
ASP A 378
 None
 1.25A 1fweC-4c60A:
17.7		 1fweC-4c60A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 10 SER A 285
SER A 304
ILE A 324
GLY A 323
GLY A 416
 None
 1.21A 1mehA-4c60A:
3.8		 1mehA-4c60A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		6 / 12 GLY A 459
ALA A 431
ASP A 432
GLY A 428
VAL A  49
ILE A  72
 None
 1.49A 1muiB-4c60A:
undetectable		 1muiB-4c60A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		3 / 3 THR A 385
PRO A 381
TYR A 154
 None
 0.49A 2dxrA-4c60A:
undetectable		 2dxrA-4c60A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 8 HIS A 307
SER A 304
SER A 414
ASP A 378
 None
 1.19A 2obvA-4c60A:
undetectable		 2obvA-4c60A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 8 HIS A 307
SER A 304
SER A 414
ASP A 378
 None
 1.24A 2p02A-4c60A:
undetectable		 2p02A-4c60A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 10 THR A 408
ILE A 404
GLY A 106
PRO A 440
ILE A 434
 None
 1.32A 2y7wB-4c60A:
undetectable		 2y7wB-4c60A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 12 ILE A 404
LEU A 389
VAL A 102
PRO A 440
LEU A 436
 None
 1.07A 3a51C-4c60A:
undetectable		 3a51C-4c60A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		3 / 3 TYR A 160
ASP A 117
HIS A 131
 None
 0.85A 3e23A-4c60A:
undetectable		 3e23A-4c60A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 8 LEU A 103
SER A  96
GLY A 465
PRO A 466
 None
 0.87A 3hcrA-4c60A:
undetectable		 3hcrA-4c60A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 12 GLY A 290
GLY A 293
ALA A 297
PRO A 260
ALA A 311
 None
 0.96A 3jb2A-4c60A:
undetectable		 3jb2A-4c60A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		3 / 3 LYS A 320
GLU A 317
TRP A 316
 None
 1.31A 3v4tH-4c60A:
undetectable		 3v4tH-4c60A:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 5 GLU A 145
GLY A 382
TYR A 151
ASP A 109
 None
 1.25A 3w9tD-4c60A:
undetectable		 3w9tD-4c60A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 4 GLU A 269
ASP A 225
ARG A 232
THR A 188
 None
 1.12A 4ej1A-4c60A:
undetectable		 4ej1A-4c60A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 8 SER A 285
SER A 304
GLY A 323
GLY A 416
 None
 0.86A 4fo4B-4c60A:
3.8		 4fo4B-4c60A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 5 HIS A 111
HIS A 191
HIS A 287
HIS A 307
ASP A 378
 None
 1.30A 4h9mA-4c60A:
18.6		 4h9mA-4c60A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 8 HIS A 307
SER A 304
SER A 414
ASP A 378
 None
 1.20A 4kttA-4c60A:
undetectable		 4kttA-4c60A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 8 HIS A 307
SER A 304
SER A 414
ASP A 378
 None
 1.20A 4kttC-4c60A:
undetectable		 4kttC-4c60A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 8 HIS A 307
SER A 304
SER A 414
ASP A 378
 None
 1.18A 4ndnA-4c60A:
undetectable		 4ndnA-4c60A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 5 THR A 377
THR A 379
ASP A 109
TYR A 151
 None
 1.35A 4oltB-4c60A:
undetectable		 4oltB-4c60A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 12 ILE A 373
THR A 372
ALA A 409
LEU A 325
LEU A 413
 None
 1.36A 4pbhA-4c60A:
undetectable		 4pbhA-4c60A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		3 / 3 TYR A 160
GLY A 219
PRO A 220
 None
 0.55A 4qwpA-4c60A:
undetectable		 4qwpA-4c60A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 7 ALA A 362
SER A 304
ALA A 328
GLU A 306
 None
 0.84A 4r1zB-4c60A:
undetectable		 4r1zB-4c60A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 5 LEU A 305
ALA A 249
VAL A 274
ILE A 273
 None
 0.92A 4xe3A-4c60A:
undetectable		 4xe3A-4c60A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 5 LEU A 305
ALA A 249
VAL A 274
ILE A 273
 None
 0.90A 4xe3B-4c60A:
undetectable		 4xe3B-4c60A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 8 HIS A 307
SER A 304
SER A 414
ASP A 378
 None
 1.21A 5a1iA-4c60A:
undetectable		 5a1iA-4c60A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 12 SER A 250
HIS A 289
HIS A 287
HIS A 307
VAL A 332
 None
 1.15A 5jnaA-4c60A:
undetectable		 5jnaA-4c60A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 12 SER A 250
HIS A 289
HIS A 287
HIS A 307
VAL A 332
 None
 1.18A 5jnaB-4c60A:
undetectable		 5jnaB-4c60A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 11 SER A 250
HIS A 289
HIS A 287
HIS A 307
VAL A 332
 None
 1.13A 5jnaC-4c60A:
undetectable		 5jnaC-4c60A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 12 SER A 250
HIS A 289
HIS A 287
HIS A 307
VAL A 332
 None
 1.19A 5jnaD-4c60A:
undetectable		 5jnaD-4c60A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 8 PRO A  87
ALA A  69
ALA A  78
GLU A 427
 None
 0.70A 5mvmA-4c60A:
undetectable
5mvmB-4c60A:
undetectable		 5mvmA-4c60A:
10.34
5mvmB-4c60A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AY6_A_VORA501_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 9 TYR A 363
ALA A 403
ALA A 406
LEU A 325
CYH A 110
 None
 1.38A 6ay6A-4c60A:
undetectable		 6ay6A-4c60A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		6 / 12 GLY A 159
VAL A 244
ILE A 173
GLY A 136
ALA A 165
ALA A 167
 None
 1.36A 6c2mD-4c60A:
undetectable		 6c2mD-4c60A:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 5 ARG A 330
ALA A 328
TYR A 326
ILE A 367
 None
 1.37A 6f6sA-4c60A:
undetectable
6f6sB-4c60A:
undetectable		 6f6sA-4c60A:
10.80
6f6sB-4c60A:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 8 HIS A 307
SER A 304
SER A 414
ASP A 378
 None
 1.18A 6fbnB-4c60A:
undetectable		 6fbnB-4c60A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 8 HIS A 307
SER A 304
SER A 414
ASP A 378
 None
 1.19A 6fboA-4c60A:
undetectable		 6fboA-4c60A:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 8 HIS A 307
SER A 304
SER A 414
ASP A 378
 None
 1.20A 6fcdA-4c60A:
undetectable		 6fcdA-4c60A:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		5 / 12 LEU A 107
GLY A 376
ALA A 407
ASP A 378
PRO A 384
 None
 0.97A 6iftA-4c60A:
undetectable		 6iftA-4c60A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 4c60 OCHRATOXINASE
(Aspergillus
niger) 		4 / 7 SER A 304
ALA A 374
ILE A 367
ALA A 366
 None
 0.76A 6ma7A-4c60A:
undetectable		 6ma7A-4c60A:
11.52