SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c6o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 4c6o CAD PROTEIN
(Homo
sapiens) 		3 / 3 ALA A1616
VAL A1670
TRP A1674
 None
 0.97A 1c4dA-4c6oA:
undetectable
1c4dB-4c6oA:
undetectable		 1c4dA-4c6oA:
4.36
1c4dB-4c6oA:
4.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 4c6o CAD PROTEIN
(Homo
sapiens) 		3 / 3 TRP A1674
ALA A1616
VAL A1670
 None
 0.92A 1c4dA-4c6oA:
undetectable
1c4dB-4c6oA:
undetectable		 1c4dA-4c6oA:
4.36
1c4dB-4c6oA:
4.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 4c6o CAD PROTEIN
(Homo
sapiens) 		3 / 3 ALA A1616
VAL A1670
TRP A1674
 None
 0.70A 1c4dC-4c6oA:
undetectable
1c4dD-4c6oA:
undetectable		 1c4dC-4c6oA:
4.36
1c4dD-4c6oA:
4.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 4c6o CAD PROTEIN
(Homo
sapiens) 		3 / 3 TRP A1674
ALA A1616
VAL A1670
 None
 0.52A 1c4dC-4c6oA:
undetectable
1c4dD-4c6oA:
undetectable		 1c4dC-4c6oA:
4.36
1c4dD-4c6oA:
4.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 5 HIS A1471
HIS A1590
HIS A1614
ASP A1686
 ZN  A2822 ( 3.2A)
ZN  A2823 (-3.0A)
ZN  A2823 (-3.2A)
ZN  A2822 (-2.6A)
 0.59A 1e9yB-4c6oA:
18.9		 1e9yB-4c6oA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 6 HIS A1471
HIS A1473
HIS A1590
HIS A1614
ASP A1686
 ZN  A2822 ( 3.2A)
ZN  A2822 ( 3.2A)
ZN  A2823 (-3.0A)
ZN  A2823 (-3.2A)
ZN  A2822 (-2.6A)
 0.62A 1fweC-4c6oA:
5.4		 1fweC-4c6oA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 7 TRP A1581
THR A1547
GLY A1550
LEU A1535
 None
 0.83A 1gtiA-4c6oA:
undetectable		 1gtiA-4c6oA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 7 TRP A1581
THR A1547
GLY A1550
LEU A1535
 None
 0.89A 1gtiD-4c6oA:
undetectable		 1gtiD-4c6oA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 4 HIS A1687
ALA A1688
PHE A1704
GLY A1706
 None
FMT  A2824 ( 3.6A)
None
None
 1.32A 1mj2B-4c6oA:
undetectable		 1mj2B-4c6oA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 4 HIS A1687
ALA A1688
PHE A1704
GLY A1706
 None
FMT  A2824 ( 3.6A)
None
None
 1.23A 1mj2D-4c6oA:
undetectable		 1mj2D-4c6oA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 4 HIS A1687
ALA A1688
PHE A1704
GLY A1706
 None
FMT  A2824 ( 3.6A)
None
None
 1.32A 1mjoB-4c6oA:
undetectable		 1mjoB-4c6oA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 4 HIS A1687
ALA A1688
PHE A1704
GLY A1706
 None
FMT  A2824 ( 3.6A)
None
None
 1.33A 1mjoA-4c6oA:
undetectable		 1mjoA-4c6oA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 12 HIS A1647
GLY A1665
GLU A1592
GLN A1593
VAL A1670
 None
 1.02A 1qu3A-4c6oA:
undetectable		 1qu3A-4c6oA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 4c6o CAD PROTEIN
(Homo
sapiens) 		3 / 3 ALA A1616
VAL A1670
TRP A1674
 None
 0.68A 1tkqB-4c6oA:
undetectable		 1tkqB-4c6oA:
4.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 9 GLU A1592
LEU A1650
LEU A1664
HIS A1642
ARG A1617
 None
 1.48A 2bxcB-4c6oA:
undetectable		 2bxcB-4c6oA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 7 LEU A1729
ARG A1722
THR A1716
LEU A1715
 None
 1.09A 2eikA-4c6oA:
undetectable
2eikJ-4c6oA:
undetectable		 2eikA-4c6oA:
23.84
2eikJ-4c6oA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 6 PRO A1504
HIS A1577
ASP A1569
TYR A1558
 KCX  A1556 ( 4.1A)
None
None
KCX  A1556 ( 3.6A)
 1.40A 2lh8A-4c6oA:
undetectable		 2lh8A-4c6oA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 12 LEU A1474
GLY A1526
ALA A1523
ALA A1519
LEU A1533
 None
 0.91A 3p5nA-4c6oA:
undetectable		 3p5nA-4c6oA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 12 LEU A1474
GLY A1526
ALA A1523
ALA A1519
LEU A1533
 None
 0.91A 3p5nB-4c6oA:
undetectable		 3p5nB-4c6oA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 8 ASP A1686
SER A1613
HIS A1471
GLU A1592
 ZN  A2822 (-2.6A)
FMT  A2827 (-3.8A)
ZN  A2822 ( 3.2A)
None
 1.09A 3sg9B-4c6oA:
undetectable		 3sg9B-4c6oA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4c6o CAD PROTEIN
(Homo
sapiens) 		3 / 3 THR A1595
VAL A1599
GLU A1620
 None
 0.71A 3v4tA-4c6oA:
1.9
3v4tD-4c6oA:
1.4		 3v4tA-4c6oA:
23.68
3v4tD-4c6oA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 5 HIS A1471
HIS A1590
HIS A1614
ASP A1686
 ZN  A2822 ( 3.2A)
ZN  A2823 (-3.0A)
ZN  A2823 (-3.2A)
ZN  A2822 (-2.6A)
 0.59A 4h9mA-4c6oA:
21.1		 4h9mA-4c6oA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 4 HIS A1770
GLU A1694
HIS A1690
LEU A1474
 None
None
FMT  A2824 (-4.2A)
None
 1.25A 4m2rA-4c6oA:
undetectable		 4m2rA-4c6oA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 11 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.03A 4qvlK-4c6oA:
undetectable
4qvlL-4c6oA:
undetectable		 4qvlK-4c6oA:
20.34
4qvlL-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 11 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.02A 4qvlY-4c6oA:
undetectable
4qvlZ-4c6oA:
undetectable		 4qvlY-4c6oA:
20.34
4qvlZ-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 9 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.03A 4qvmK-4c6oA:
undetectable
4qvmL-4c6oA:
undetectable		 4qvmK-4c6oA:
20.34
4qvmL-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 10 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.03A 4qvmY-4c6oA:
undetectable
4qvmZ-4c6oA:
undetectable		 4qvmY-4c6oA:
20.34
4qvmZ-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 10 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.03A 4qvpK-4c6oA:
undetectable
4qvpL-4c6oA:
undetectable		 4qvpK-4c6oA:
20.34
4qvpL-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 10 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.02A 4qvpY-4c6oA:
undetectable
4qvpZ-4c6oA:
undetectable		 4qvpY-4c6oA:
20.34
4qvpZ-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 11 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.02A 4qw1K-4c6oA:
undetectable
4qw1L-4c6oA:
undetectable		 4qw1K-4c6oA:
20.06
4qw1L-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 10 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.02A 4qw1Y-4c6oA:
undetectable
4qw1Z-4c6oA:
undetectable		 4qw1Y-4c6oA:
20.06
4qw1Z-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 10 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.03A 4qw3K-4c6oA:
undetectable
4qw3L-4c6oA:
undetectable		 4qw3K-4c6oA:
20.34
4qw3L-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 10 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.03A 4qw3Y-4c6oA:
undetectable
4qw3Z-4c6oA:
undetectable		 4qw3Y-4c6oA:
20.34
4qw3Z-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 6 HIS A1471
HIS A1473
HIS A1590
HIS A1614
ASP A1686
 ZN  A2822 ( 3.2A)
ZN  A2822 ( 3.2A)
ZN  A2823 (-3.0A)
ZN  A2823 (-3.2A)
ZN  A2822 (-2.6A)
 0.45A 4ubpC-4c6oA:
23.5		 4ubpC-4c6oA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 4c6o CAD PROTEIN
(Homo
sapiens) 		3 / 3 ASP A1484
ARG A1528
PRO A1803
 None
 0.88A 4wanC-4c6oA:
undetectable		 4wanC-4c6oA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 11 MET A1710
LEU A1714
LEU A1729
LEU A1725
LEU A1467
 None
 1.24A 4zn7B-4c6oA:
undetectable		 4zn7B-4c6oA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 11 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.04A 5bxnY-4c6oA:
undetectable
5bxnZ-4c6oA:
undetectable		 5bxnY-4c6oA:
20.34
5bxnZ-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 9 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.02A 5d0xK-4c6oA:
undetectable
5d0xL-4c6oA:
undetectable		 5d0xK-4c6oA:
20.63
5d0xL-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 9 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 1.02A 5d0xY-4c6oA:
undetectable
5d0xZ-4c6oA:
undetectable		 5d0xY-4c6oA:
20.63
5d0xZ-4c6oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 11 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 0.97A 5lf3K-4c6oA:
undetectable
5lf3L-4c6oA:
undetectable		 5lf3K-4c6oA:
18.95
5lf3L-4c6oA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 11 ALA A1490
THR A1489
GLY A1496
GLY A1495
ALA A1494
 None
 0.96A 5lf3Y-4c6oA:
undetectable
5lf3Z-4c6oA:
undetectable		 5lf3Y-4c6oA:
18.95
5lf3Z-4c6oA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4c6o CAD PROTEIN
(Homo
sapiens) 		4 / 6 LEU A1729
ARG A1722
THR A1716
LEU A1715
 None
 1.08A 5x1fA-4c6oA:
undetectable
5x1fJ-4c6oA:
undetectable		 5x1fA-4c6oA:
23.84
5x1fJ-4c6oA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 5 GLY A1543
THR A1544
HIS A1577
SER A1539
SER A1538
 None
 1.08A 6jmjA-4c6oA:
undetectable		 6jmjA-4c6oA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 7 GLY A1543
THR A1544
HIS A1577
SER A1539
SER A1538
 None
 1.08A 6jnhA-4c6oA:
undetectable		 6jnhA-4c6oA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4c6o CAD PROTEIN
(Homo
sapiens) 		5 / 6 GLY A1543
THR A1544
HIS A1577
SER A1539
SER A1538
 None
 1.08A 6jogA-4c6oA:
undetectable		 6jogA-4c6oA:
18.37