SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J96_B_TESB904_1 (3ALPHA-HYDROXYSTEROI D DEHYDROGENASE TYPE 3)	4c79	SMOOTHENED (Danio rerio)	4 / 7	VAL A 99 ILE A 100 GLU A 136 TRP A 141	None	0.80A	1j96B-4c79A: undetectable	1j96B-4c79A: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZJQ_A_NCAA300_0 (PROTOGLOBIN)	4c79	SMOOTHENED (Danio rerio)	4 / 7	TYR A 108 VAL A 107 PHE A 144 ILE A 100	None	0.95A	3zjqA-4c79A: undetectable	3zjqA-4c79A: 18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZJQ_B_NCAB300_0 (PROTOGLOBIN)	4c79	SMOOTHENED (Danio rerio)	4 / 7	TYR A 108 VAL A 107 PHE A 144 ILE A 100	None	0.96A	3zjqB-4c79A: undetectable	3zjqB-4c79A: 18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A84_A_DXCA1161_0 (MAJOR POLLEN ALLERGEN BET V 1-A)	4c79	SMOOTHENED (Danio rerio)	5 / 12	PRO A 142 LEU A 145 TYR A 108 VAL A 107 SER A 74	None	1.35A	4a84A-4c79A: undetectable	4a84A-4c79A: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FN9_A_STRA301_1 (STEROID RECEPTOR 2)	4c79	SMOOTHENED (Danio rerio)	5 / 12	LEU A 57 LEU A 104 LEU A 103 ALA A 106 ALA A 71	None None None None NA A1160 (-4.8A)	1.12A	4fn9A-4c79A: undetectable	4fn9A-4c79A: 20.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1J96_B_TESB904_1","3ALPHA-HYDROXYSTEROID DEHYDROGENASE TYPE 3","4c79","SMOOTHENED","Danio rerio",4,"VAL A  99;ILE A 100;GLU A 136;TRP A 141","None","0.80A","1j96B-4c79A:undetectable","1j96B-4c79A:19.82"],["3ZJQ_A_NCAA300_0","PROTOGLOBIN","4c79","SMOOTHENED","Danio rerio",4,"TYR A 108;VAL A 107;PHE A 144;ILE A 100","None","0.95A","3zjqA-4c79A:undetectable","3zjqA-4c79A:18.78"],["3ZJQ_B_NCAB300_0","PROTOGLOBIN","4c79","SMOOTHENED","Danio rerio",4,"TYR A 108;VAL A 107;PHE A 144;ILE A 100","None","0.96A","3zjqB-4c79A:undetectable","3zjqB-4c79A:18.78"],["4A84_A_DXCA1161_0","MAJOR POLLEN ALLERGEN BET V 1-A","4c79","SMOOTHENED","Danio rerio",5,"PRO A 142;LEU A 145;TYR A 108;VAL A 107;SER A  74","None","1.35A","4a84A-4c79A:undetectable","4a84A-4c79A:20.92"],["4FN9_A_STRA301_1","STEROID RECEPTOR 2","4c79","SMOOTHENED","Danio rerio",5,"LEU A  57;LEU A 104;LEU A 103;ALA A 106;ALA A  71","None;None;None;None; NA A1160 (-4.8A)","1.12A","4fn9A-4c79A:undetectable","4fn9A-4c79A:20.30"]]