SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c7p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 4c7p RALF
(Legionella
pneumophila) 		3 / 3 ARG A 293
ASP A  60
ASN A  69
 None
 0.95A 1nbhA-4c7pA:
undetectable		 1nbhA-4c7pA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 4c7p RALF
(Legionella
pneumophila) 		3 / 3 ARG A 293
ASP A  60
ASN A  69
 None
 0.93A 1nbhD-4c7pA:
undetectable		 1nbhD-4c7pA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4c7p RALF
(Legionella
pneumophila) 		5 / 12 ILE A 275
LEU A 264
VAL A 241
ILE A 237
ILE A 296
 None
 0.79A 1oipA-4c7pA:
undetectable		 1oipA-4c7pA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4c7p RALF
(Legionella
pneumophila) 		5 / 10 LEU A 110
SER A 113
PHE A  94
PHE A  76
THR A  77
 None
 0.91A 1wygA-4c7pA:
2.4		 1wygA-4c7pA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4c7p RALF
(Legionella
pneumophila) 		4 / 7 PHE A 114
THR A 139
LEU A 135
VAL A 126
 None
 1.05A 1yrcA-4c7pA:
undetectable		 1yrcA-4c7pA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4c7p RALF
(Legionella
pneumophila) 		4 / 7 PHE A 114
THR A 139
LEU A 135
VAL A 126
 None
 1.03A 1yrdA-4c7pA:
undetectable		 1yrdA-4c7pA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4c7p RALF
(Legionella
pneumophila) 		4 / 6 PHE A 114
THR A 139
LEU A 135
VAL A 126
 None
 1.00A 2feuA-4c7pA:
undetectable		 2feuA-4c7pA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4c7p RALF
(Legionella
pneumophila) 		4 / 5 PRO A 201
PRO A 101
ILE A 107
GLY A 102
 None
 1.05A 2jkjD-4c7pA:
undetectable		 2jkjD-4c7pA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4c7p RALF
(Legionella
pneumophila) 		4 / 5 PRO A 201
PRO A 101
ILE A 107
GLY A 102
 None
 1.04A 2jkjF-4c7pA:
undetectable		 2jkjF-4c7pA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 4c7p RALF
(Legionella
pneumophila) 		4 / 7 GLY A 169
GLY A 168
VAL A 126
LEU A 135
 None
 0.65A 2oa1B-4c7pA:
2.8		 2oa1B-4c7pA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 4c7p RALF
(Legionella
pneumophila) 		4 / 7 ILE A 107
TYR A 258
TYR A 278
ASP A 246
 None
 1.09A 2qebA-4c7pA:
undetectable		 2qebA-4c7pA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 4c7p RALF
(Legionella
pneumophila) 		5 / 11 LEU A  53
ILE A  27
ARG A 109
GLU A  66
LEU A  62
 None
 1.12A 2v0mA-4c7pA:
undetectable		 2v0mA-4c7pA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4c7p RALF
(Legionella
pneumophila) 		4 / 6 PHE A 114
THR A 139
LEU A 135
VAL A 126
 None
 1.07A 2zuiA-4c7pA:
undetectable		 2zuiA-4c7pA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4c7p RALF
(Legionella
pneumophila) 		4 / 7 PHE A 114
THR A 139
LEU A 135
VAL A 126
 None
 1.05A 2zwtA-4c7pA:
undetectable		 2zwtA-4c7pA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4c7p RALF
(Legionella
pneumophila) 		4 / 7 PHE A 114
THR A 139
LEU A 135
VAL A 126
 None
 1.05A 2zwuA-4c7pA:
undetectable		 2zwuA-4c7pA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4c7p RALF
(Legionella
pneumophila) 		4 / 7 PHE A 114
THR A 139
LEU A 135
VAL A 126
 None
 1.03A 3fwfA-4c7pA:
undetectable		 3fwfA-4c7pA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4c7p RALF
(Legionella
pneumophila) 		4 / 7 PHE A 114
THR A 139
LEU A 135
VAL A 126
 None
 1.05A 3fwjA-4c7pA:
undetectable		 3fwjA-4c7pA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 4c7p RALF
(Legionella
pneumophila) 		5 / 10 LEU A 264
ALA A 308
ILE A 305
GLY A 202
ILE A 295
 None
 1.05A 3ogpA-4c7pA:
undetectable		 3ogpA-4c7pA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4c7p RALF
(Legionella
pneumophila) 		4 / 7 PHE A 114
THR A 139
LEU A 135
VAL A 126
 None
 1.01A 3wrmF-4c7pA:
undetectable		 3wrmF-4c7pA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 4c7p RALF
(Legionella
pneumophila) 		4 / 7 VAL A 233
LEU A 264
VAL A 245
THR A 243
 None
 1.00A 5e4dA-4c7pA:
2.4
5e4dB-4c7pA:
2.5		 5e4dA-4c7pA:
22.08
5e4dB-4c7pA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4c7p RALF
(Legionella
pneumophila) 		4 / 7 ILE A  36
VAL A  58
ILE A  24
PHE A  76
 None
 0.91A 5hieC-4c7pA:
undetectable		 5hieC-4c7pA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 4c7p RALF
(Legionella
pneumophila) 		5 / 12 SER A  86
ASN A 122
GLN A 120
GLN A 121
GLY A  90
 None
 1.33A 5oj0A-4c7pA:
undetectable		 5oj0A-4c7pA:
21.52