SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4c7q RNA-BINDING
GLYCINE-RICH PROTEIN
(Nicotiana
tabacum) 		4 / 7 THR A  17
VAL A  10
GLY A  11
ASP A  71
 None
 0.87A 2a1mA-4c7qA:
undetectable		 2a1mA-4c7qA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 4c7q RNA-BINDING
GLYCINE-RICH PROTEIN
(Nicotiana
tabacum) 		4 / 8 SER A  46
ASP A  73
LEU A  72
ASP A  19
 None
 1.17A 3n2oC-4c7qA:
undetectable
3n2oD-4c7qA:
undetectable		 3n2oC-4c7qA:
9.33
3n2oD-4c7qA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 4c7q RNA-BINDING
GLYCINE-RICH PROTEIN
(Nicotiana
tabacum) 		4 / 7 ILE A  64
SER A  84
TYR A   6
ARG A  85
 None
 0.97A 3pglA-4c7qA:
undetectable		 3pglA-4c7qA:
18.29