SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c7u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 4c7u SUPEROXIDE DISMUTASE
[MN] 1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		6 / 12 SER A 124
GLN A 146
LEU A  81
HIS A  74
ILE A  22
ALA A 168
 None
MN  A 302 ( 4.7A)
None
MN  A 302 (-3.4A)
None
MN  A 302 ( 4.9A)
 1.14A 2bxcA-4c7uA:
undetectable		 2bxcA-4c7uA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4c7u SUPEROXIDE DISMUTASE
[MN] 1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 GLY A  69
GLN A 146
HIS A  30
LEU A   4
HIS A  26
 None
MN  A 302 ( 4.7A)
None
None
MN  A 302 (-3.4A)
 1.39A 2prgA-4c7uA:
0.0		 2prgA-4c7uA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 4c7u SUPEROXIDE DISMUTASE
[MN] 1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 LEU A 181
VAL A 184
ILE A  18
TYR A 169
HIS A  26
 None
None
None
None
MN  A 302 (-3.4A)
 1.20A 3hgiA-4c7uA:
undetectable		 3hgiA-4c7uA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 4c7u SUPEROXIDE DISMUTASE
[MN] 1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 11 ALA A 120
VAL A 164
GLY A 125
ALA A 144
LEU A 181
 None
 1.04A 3sm2B-4c7uA:
undetectable		 3sm2B-4c7uA:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)		 4c7u SUPEROXIDE DISMUTASE
[MN] 1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		4 / 5 HIS A  74
HIS A 167
GLN A 146
TYR A  34
 MN  A 302 (-3.4A)
MN  A 302 (-3.4A)
MN  A 302 ( 4.7A)
None
 1.30A 4gboA-4c7uA:
undetectable		 4gboA-4c7uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 4c7u SUPEROXIDE DISMUTASE
[MN] 1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		4 / 7 ILE A  18
TYR A 180
PHE A  77
ASN A  80
 None
 1.42A 4o7gA-4c7uA:
undetectable
4o7gB-4c7uA:
undetectable		 4o7gA-4c7uA:
21.43
4o7gB-4c7uA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4c7u SUPEROXIDE DISMUTASE
[MN] 1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 VAL A 160
SER A 194
LEU A 107
ILE A 100
GLY A  97
 None
 1.12A 4y8wB-4c7uA:
undetectable		 4y8wB-4c7uA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_A_CUA301_0
(AA10A)		 4c7u SUPEROXIDE DISMUTASE
[MN] 1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		4 / 5 HIS A  74
HIS A 167
GLN A 146
TYR A  34
 MN  A 302 (-3.4A)
MN  A 302 (-3.4A)
MN  A 302 ( 4.7A)
None
 1.31A 5uizA-4c7uA:
undetectable		 5uizA-4c7uA:
22.27