SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 4c82 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
falciparum) 		5 / 12 VAL A 112
ILE A 120
ILE A 197
ASN A 196
LEU A 100
 None
 1.18A 1fm4A-4c82A:
undetectable		 1fm4A-4c82A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 4c82 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
falciparum) 		4 / 5 LEU A 100
GLY A 118
HIS A  73
ILE A 227
 None
None
ZN  A1240 (-3.2A)
None
 0.87A 1xf1A-4c82A:
2.1		 1xf1A-4c82A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 4c82 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
falciparum) 		4 / 6 LEU A 100
GLY A 118
HIS A  73
ILE A 227
 None
None
ZN  A1240 (-3.2A)
None
 0.90A 1xf1B-4c82A:
undetectable		 1xf1B-4c82A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4c82 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
falciparum) 		5 / 11 ILE A 165
ALA A 132
ASN A 174
ILE A 208
ILE A 172
 None
 1.28A 2blaA-4c82A:
undetectable		 2blaA-4c82A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 4c82 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
falciparum) 		5 / 12 PRO A 184
ALA A 155
LEU A 158
THR A 199
ILE A 193
 None
 1.03A 2jjpA-4c82A:
undetectable		 2jjpA-4c82A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 4c82 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
falciparum) 		5 / 9 GLY A 131
ALA A 132
ILE A  66
ILE A 125
LEU A 235
 None
 1.00A 3ogpA-4c82A:
undetectable		 3ogpA-4c82A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 4c82 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
falciparum) 		5 / 11 ILE A 197
LEU A 158
ILE A 186
VAL A 179
VAL A 210
 None
 1.13A 4h1nA-4c82A:
undetectable		 4h1nA-4c82A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)		 4c82 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
falciparum) 		5 / 10 ILE A 189
ASP A 119
LEU A 102
GLY A 103
ASN A 196
 None
 1.49A 6r2eC-4c82A:
undetectable		 6r2eC-4c82A:
19.17