SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c89'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		4 / 8 GLY A 107
TYR A 110
SER A 174
HIS A 313
 None
 0.89A 1ax9A-4c89A:
15.3		 1ax9A-4c89A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		6 / 12 GLY A 106
GLY A 107
TYR A 110
SER A 174
PHE A 238
HIS A 313
 None
 0.89A 1dx6A-4c89A:
16.0		 1dx6A-4c89A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 12 GLY A 107
TYR A 110
SER A 174
PHE A 238
HIS A 313
 None
 0.99A 1maaC-4c89A:
8.8		 1maaC-4c89A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		4 / 8 GLY A 107
TYR A 110
SER A 174
HIS A 313
 None
 0.60A 1maaD-4c89A:
14.3		 1maaD-4c89A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		6 / 12 GLY A 106
GLY A 107
TYR A 110
SER A 174
PHE A 238
HIS A 313
 None
 0.87A 1qtiA-4c89A:
15.4		 1qtiA-4c89A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 12 TYR A 234
LEU A  38
LEU A  35
ILE A 223
LEU A 231
 None
 1.23A 1tw4B-4c89A:
undetectable		 1tw4B-4c89A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		4 / 5 TYR A 248
ILE A 244
ARG A  55
GLY A 111
 None
 1.32A 1ve9A-4c89A:
undetectable		 1ve9A-4c89A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 12 GLY A 106
GLY A 107
SER A 174
PHE A 238
HIS A 313
 None
 0.73A 1w6rA-4c89A:
16.0		 1w6rA-4c89A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 12 GLY A 106
GLY A 107
TYR A 110
SER A 174
HIS A 313
 None
 0.37A 1w6rA-4c89A:
16.0		 1w6rA-4c89A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 10 GLY A 106
GLY A 107
SER A 174
PHE A 238
HIS A 313
 None
 0.74A 1w76B-4c89A:
15.1		 1w76B-4c89A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 10 GLY A 106
GLY A 107
TYR A 110
SER A 174
HIS A 313
 None
 0.36A 1w76B-4c89A:
15.1		 1w76B-4c89A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		4 / 7 GLY A 107
SER A 174
PHE A 238
HIS A 313
 None
 1.06A 2ackA-4c89A:
16.3		 2ackA-4c89A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		4 / 7 GLY A 107
TYR A 110
SER A 174
HIS A 313
 None
 0.94A 2ackA-4c89A:
16.3		 2ackA-4c89A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 12 PHE A 156
TYR A 158
ALA A  80
ALA A 183
GLY A 148
 None
 1.27A 2igtC-4c89A:
3.1		 2igtC-4c89A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		4 / 8 ALA A  62
VAL A 119
THR A 118
ASP A 320
 None
 0.99A 2kotB-4c89A:
undetectable		 2kotB-4c89A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_D_TOPD200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 9 ALA A 177
VAL A 204
ILE A 261
PHE A 109
TYR A 137
 None
 1.23A 3fl9D-4c89A:
undetectable		 3fl9D-4c89A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 12 PHE A 156
ILE A 155
LEU A 101
ARG A  76
VAL A  87
 None
 1.17A 3fpjB-4c89A:
2.7		 3fpjB-4c89A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 12 GLY A 106
ALA A 314
PRO A 114
PHE A 104
ALA A 108
 None
 1.07A 3jb1A-4c89A:
undetectable		 3jb1A-4c89A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		4 / 7 GLY A 107
SER A 174
PHE A 285
HIS A 313
 None
 0.55A 3o9mA-4c89A:
2.2		 3o9mA-4c89A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 12 GLY A 106
ASN A 117
PHE A 285
GLY A 176
ASN A 178
 None
 1.32A 3ps9A-4c89A:
undetectable		 3ps9A-4c89A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 12 HIS A 313
ASP A 283
GLY A 106
SER A 174
ALA A 316
 None
 1.04A 3sueB-4c89A:
undetectable		 3sueB-4c89A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 12 HIS A 313
ASP A 283
GLY A 106
SER A 174
ALA A 316
 None
 1.05A 3sufA-4c89A:
undetectable		 3sufA-4c89A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		4 / 5 GLU A  88
GLY A 115
TYR A 103
ASP A 173
 None
 1.43A 3w9tD-4c89A:
undetectable		 3w9tD-4c89A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		6 / 12 GLY A 106
GLY A 107
TYR A 110
SER A 174
PHE A 238
HIS A 313
 None
 0.78A 4ey6A-4c89A:
16.5		 4ey6A-4c89A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		6 / 12 GLY A 106
GLY A 107
TYR A 110
SER A 174
PHE A 238
HIS A 313
 None
 0.78A 4ey6B-4c89A:
14.5		 4ey6B-4c89A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		5 / 12 ALA A 314
GLY A 107
GLY A 106
ILE A 244
LEU A  47
 None
 1.07A 4n48B-4c89A:
undetectable		 4n48B-4c89A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		4 / 5 TYR A  -3
SER A 128
ALA A 125
GLN A  93
 None
 1.12A 5n4iA-4c89A:
undetectable		 5n4iA-4c89A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 4c89 ESTERASE
(Lactobacillus
plantarum) 		4 / 5 ILE A 195
THR A 184
THR A 166
LEU A 133
 None
 1.13A 6f3mD-4c89A:
5.5		 6f3mD-4c89A:
22.62