SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 4c94 FRA A 3 ALLERGEN
(Fragaria
x
ananassa) 		6 / 12 ILE A  57
TYR A  82
TYR A  84
ILE A  99
TYR A 120
LEU A 143
 KXN  A 160 ( 4.7A)
None
None
None
None
None
 0.98A 1fm4A-4c94A:
24.2		 1fm4A-4c94A:
55.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 4c94 FRA A 3 ALLERGEN
(Fragaria
x
ananassa) 		4 / 8 PHE A 144
PHE A  10
TYR A 101
TYR A  84
 None
 1.35A 2aoxA-4c94A:
undetectable		 2aoxA-4c94A:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4c94 FRA A 3 ALLERGEN
(Fragaria
x
ananassa) 		6 / 12 ASP A  28
LYS A  55
ILE A  57
VAL A  68
TYR A  82
LEU A 143
 None
None
KXN  A 160 ( 4.7A)
None
None
None
 0.93A 4a81A-4c94A:
24.6		 4a81A-4c94A:
58.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4c94 FRA A 3 ALLERGEN
(Fragaria
x
ananassa) 		5 / 12 LYS A  55
VAL A  68
TYR A  82
TYR A  84
LEU A 143
 None
 0.92A 4a83A-4c94A:
24.6		 4a83A-4c94A:
58.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4c94 FRA A 3 ALLERGEN
(Fragaria
x
ananassa) 		6 / 12 ASP A  28
ILE A  57
TYR A  82
TYR A  84
ILE A  99
LEU A 143
 None
KXN  A 160 ( 4.7A)
None
None
None
None
 0.93A 4a84A-4c94A:
24.2		 4a84A-4c94A:
58.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4c94 FRA A 3 ALLERGEN
(Fragaria
x
ananassa) 		6 / 12 ASP A  28
TYR A  82
TYR A  84
ILE A  99
TYR A 120
LEU A 143
 None
 0.69A 4a84A-4c94A:
24.2		 4a84A-4c94A:
58.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4c94 FRA A 3 ALLERGEN
(Fragaria
x
ananassa) 		5 / 12 GLY A  62
GLY A  60
LEU A  59
ALA A 135
ASP A  90
 KXN  A 160 ( 4.8A)
None
KXN  A 160 (-4.4A)
None
KXN  A 160 (-4.4A)
 0.96A 5c0oF-4c94A:
undetectable		 5c0oF-4c94A:
undetectable