SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 4c98 CAS6B
(Thermus
thermophilus) 		5 / 9 ARG A  71
LEU A 260
ILE A 164
PRO A 263
VAL A 262
 None
 1.14A 2r5qA-4c98A:
undetectable		 2r5qA-4c98A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 4c98 CAS6B
(Thermus
thermophilus) 		5 / 9 ARG A  71
LEU A 260
ILE A 164
PRO A 263
VAL A 262
 None
 1.14A 2r5qC-4c98A:
undetectable		 2r5qC-4c98A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 4c98 CAS6B
(Thermus
thermophilus) 		3 / 3 PHE A 138
SER A 167
LEU A 163
 None
 0.72A 2w1bA-4c98A:
undetectable		 2w1bA-4c98A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 4c98 CAS6B
(Thermus
thermophilus) 		5 / 10 ALA A  86
LEU A   9
LEU A   7
LEU A 104
ARG A  32
 None
 1.13A 2xn6A-4c98A:
undetectable
2xn6B-4c98A:
undetectable		 2xn6A-4c98A:
23.37
2xn6B-4c98A:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4c98 CAS6B
(Thermus
thermophilus) 		3 / 3 VAL A 250
SER A 248
LEU A 168
 None
 0.66A 3n8xA-4c98A:
undetectable		 3n8xA-4c98A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 4c98 CAS6B
(Thermus
thermophilus) 		5 / 11 LEU A  70
LEU A  41
PHE A  27
PRO A 255
ALA A  22
 None
 1.49A 4hwkB-4c98A:
undetectable		 4hwkB-4c98A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 4c98 CAS6B
(Thermus
thermophilus) 		5 / 12 LEU A  70
LEU A  41
PHE A  27
PRO A 255
ALA A  22
 None
 1.48A 4hwkC-4c98A:
undetectable		 4hwkC-4c98A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 4c98 CAS6B
(Thermus
thermophilus) 		5 / 11 LEU A  70
LEU A  41
PHE A  27
PRO A 255
ALA A  22
 None
 1.50A 4hwkD-4c98A:
undetectable		 4hwkD-4c98A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 4c98 CAS6B
(Thermus
thermophilus) 		5 / 11 VAL A 250
GLY A 251
ALA A 245
SER A 167
LEU A 168
 None
 1.22A 5x6yA-4c98A:
undetectable		 5x6yA-4c98A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 4c98 CAS6B
(Thermus
thermophilus) 		5 / 10 VAL A 250
GLY A 251
ALA A 245
SER A 167
LEU A 168
 None
 1.14A 5x6yB-4c98A:
undetectable		 5x6yB-4c98A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 4c98 CAS6B
(Thermus
thermophilus) 		3 / 3 ASP A 160
LEU A 163
ARG A 189
 None
 0.88A 7dfrA-4c98A:
undetectable		 7dfrA-4c98A:
19.78