SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c9g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 4c9g ADP, ATP CARRIER
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 ALA A 241
VAL A 236
TRP A 235
 ALA  A 241 ( 0.0A)
VAL  A 236 ( 0.6A)
TRP  A 235 ( 0.5A)
 0.88A 1kqeB-4c9gA:
undetectable
1kqeD-4c9gA:
undetectable		 1kqeB-4c9gA:
3.45
1kqeD-4c9gA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 4c9g ADP, ATP CARRIER
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 6 TYR A 177
GLY A 192
PHE A 193
ARG A 252
 TYR  A 177 ( 1.3A)
GLY  A 192 (-0.0A)
PHE  A 193 (-1.3A)
ARG  A 252 (-0.6A)
 1.38A 2a3cA-4c9gA:
undetectable		 2a3cA-4c9gA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4c9g ADP, ATP CARRIER
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 GLY A  89
SER A  85
ARG A 152
GLU A  81
 GLY  A  89 (-0.0A)
SER  A  85 ( 0.0A)
ARG  A 152 ( 0.6A)
GLU  A  81 ( 0.6A)
 0.93A 2c8aB-4c9gA:
undetectable		 2c8aB-4c9gA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4c9g ADP, ATP CARRIER
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 GLY A  89
SER A  85
ARG A 152
GLU A  81
 GLY  A  89 (-0.0A)
SER  A  85 ( 0.0A)
ARG  A 152 ( 0.6A)
GLU  A  81 ( 0.6A)
 0.99A 2c8aD-4c9gA:
undetectable		 2c8aD-4c9gA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 4c9g ADP, ATP CARRIER
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 142
SER A 141
ILE A 200
SER A 133
GLY A 134
 LEU  A 142 ( 0.6A)
SER  A 141 ( 0.0A)
ILE  A 200 ( 0.7A)
SER  A 133 ( 0.0A)
GLY  A 134 ( 0.0A)
 1.33A 3iluB-4c9gA:
undetectable
3iluE-4c9gA:
undetectable		 3iluB-4c9gA:
22.02
3iluE-4c9gA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 4c9g ADP, ATP CARRIER
PROTEIN 2
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 200
SER A 133
GLY A 134
LEU A 142
SER A 141
 ILE  A 200 ( 0.7A)
SER  A 133 ( 0.0A)
GLY  A 134 ( 0.0A)
LEU  A 142 ( 0.6A)
SER  A 141 ( 0.0A)
 1.36A 3iluB-4c9gA:
undetectable
3iluE-4c9gA:
undetectable		 3iluB-4c9gA:
22.02
3iluE-4c9gA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4c9g ADP, ATP CARRIER
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A  93
ALA A  92
ARG A 154
ALA A 156
 ASN  A  93 ( 0.6A)
ALA  A  92 ( 0.0A)
ARG  A 154 ( 0.6A)
ALA  A 156 ( 0.0A)
 0.91A 3twpA-4c9gA:
undetectable		 3twpA-4c9gA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4c9g ADP, ATP CARRIER
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A  93
ALA A  92
ARG A 154
ALA A 156
 ASN  A  93 ( 0.6A)
ALA  A  92 ( 0.0A)
ARG  A 154 ( 0.6A)
ALA  A 156 ( 0.0A)
 0.97A 3twpB-4c9gA:
undetectable		 3twpB-4c9gA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4c9g ADP, ATP CARRIER
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 7 ASN A  93
ALA A  92
ARG A 154
ALA A 156
 ASN  A  93 ( 0.6A)
ALA  A  92 ( 0.0A)
ARG  A 154 ( 0.6A)
ALA  A 156 ( 0.0A)
 1.10A 3twpC-4c9gA:
undetectable		 3twpC-4c9gA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 4c9g ADP, ATP CARRIER
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 5 VAL A 251
ARG A 254
MET A 255
GLU A  56
 VAL  A 251 ( 0.6A)
ARG  A 254 ( 0.6A)
MET  A 255 (-0.0A)
GLU  A  56 ( 0.6A)
 0.82A 4hojA-4c9gA:
undetectable		 4hojA-4c9gA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 4c9g ADP, ATP CARRIER
PROTEIN 2
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 155
THR A 153
ARG A 253
SER A  42
 LEU  A 155 ( 0.6A)
THR  A 153 ( 0.8A)
ARG  A 253 ( 0.6A)
SER  A  42 ( 0.0A)
 1.17A 4qknA-4c9gA:
undetectable		 4qknA-4c9gA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 4c9g ADP, ATP CARRIER
PROTEIN 2
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  55
LEU A  58
ARG A  76
 ASP  A  55 (-0.6A)
LEU  A  58 (-0.6A)
ARG  A  76 ( 0.6A)
 0.84A 7dfrA-4c9gA:
undetectable		 7dfrA-4c9gA:
19.18