SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
4c9v RNF43
(Xenopus
tropicalis)
3 / 3 ASN A 137
ASP A 134
ASP A 168
None
0.86A 4obwD-4c9vA:
undetectable
4obwD-4c9vA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)
4c9v RNF43
(Xenopus
tropicalis)
5 / 12 LEU A 122
ALA A  67
PHE A 133
LEU A 103
VAL A 101
None
0.95A 5tudA-4c9vA:
undetectable
5tudA-4c9vA:
19.91