SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4c9y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 4c9y SPINDLE AND
KINETOCHORE-ASSOCIAT
ED PROTEIN 1
(Homo
sapiens) 		4 / 7 LEU A 101
ASN A 102
MET A   6
MET A  21
 None
 1.13A 2w8yA-4c9yA:
undetectable		 2w8yA-4c9yA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 4c9y SPINDLE AND
KINETOCHORE-ASSOCIAT
ED PROTEIN 1
(Homo
sapiens) 		4 / 6 ILE A  30
PHE A   8
PHE A  97
THR A  89
 None
 1.32A 5g08A-4c9yA:
undetectable		 5g08A-4c9yA:
21.16