SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ca9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 4ca9 39 KDA FK506-BINDING
NUCLEAR PROTEIN
(Drosophila
melanogaster) 		5 / 12 ILE A  29
LEU A  87
VAL A  85
ALA A  80
TYR A  78
 None
 1.26A 3ozuA-4ca9A:
undetectable		 3ozuA-4ca9A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 4ca9 39 KDA FK506-BINDING
NUCLEAR PROTEIN
(Drosophila
melanogaster) 		5 / 12 LEU A  65
GLY A  10
LEU A  11
SER A  86
PHE A  77
 None
 1.22A 3tbgC-4ca9A:
undetectable		 3tbgC-4ca9A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 4ca9 39 KDA FK506-BINDING
NUCLEAR PROTEIN
(Drosophila
melanogaster) 		4 / 8 SER A  30
LEU A  88
PHE A   8
TYR A  90
 None
 0.98A 4j7uD-4ca9A:
undetectable		 4j7uD-4ca9A:
15.30