SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cah'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 4cah DYSFERLIN
(Homo
sapiens) 		3 / 3 TRP B 965
GLU B1031
TYR B1014
 None
 1.09A 2a3aA-4cahB:
undetectable		 2a3aA-4cahB:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDM_A_ADNA904_1
(ATP-CITRATE SYNTHASE)		 4cah DYSFERLIN
(Homo
sapiens) 		4 / 4 THR B1001
ASP B1002
ARG B1005
LEU B1003
 None
 1.03A 5tdmA-4cahB:
undetectable		 5tdmA-4cahB:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 4cah DYSFERLIN
(Homo
sapiens) 		4 / 6 THR B1001
ASP B1002
ARG B1005
LEU B1003
 None
 0.98A 5tdzA-4cahB:
undetectable		 5tdzA-4cahB:
14.65