SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cbp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4cbp NEURAL/ECTODERMAL
DEVELOPMENT FACTOR
IMP-L2
(Drosophila
melanogaster) 		4 / 7 PHE A  35
ALA A 125
ILE A  53
PRO A  39
 None
 0.93A 1oniA-4cbpA:
undetectable
1oniB-4cbpA:
undetectable		 1oniA-4cbpA:
21.14
1oniB-4cbpA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 4cbp NEURAL/ECTODERMAL
DEVELOPMENT FACTOR
IMP-L2
(Drosophila
melanogaster) 		4 / 6 LEU A 106
GLU A 140
PRO A 139
ARG A 110
 None
 1.39A 3ltwA-4cbpA:
0.5		 3ltwA-4cbpA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 4cbp NEURAL/ECTODERMAL
DEVELOPMENT FACTOR
IMP-L2
(Drosophila
melanogaster) 		5 / 12 LEU A 161
GLY A  59
ALA A  30
GLY A 119
ASP A  31
 None
 0.88A 4dc3A-4cbpA:
undetectable		 4dc3A-4cbpA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 4cbp NEURAL/ECTODERMAL
DEVELOPMENT FACTOR
IMP-L2
(Drosophila
melanogaster) 		4 / 8 TRP A  67
LEU A  43
GLU A  52
THR A 127
 None
 0.98A 6c71B-4cbpA:
undetectable		 6c71B-4cbpA:
14.29