SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ccd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 TRP A 272
ALA A 329
VAL A 327
 None
 0.89A 1c4dA-4ccdA:
undetectable
1c4dB-4ccdA:
undetectable		 1c4dA-4ccdA:
4.07
1c4dB-4ccdA:
4.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 8 LEU A  70
ALA A 121
LEU A  79
THR A 335
 None
 0.81A 1dvtA-4ccdA:
undetectable
1dvtB-4ccdA:
undetectable		 1dvtA-4ccdA:
12.05
1dvtB-4ccdA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 9 VAL A 559
GLY A 557
ALA A 657
THR A 553
ILE A 551
 None
 1.16A 1gtnL-4ccdA:
undetectable
1gtnM-4ccdA:
undetectable		 1gtnL-4ccdA:
8.25
1gtnM-4ccdA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 10 LEU A 154
ILE A  86
GLY A  87
GLY A  88
PRO A 148
 None
 1.06A 1k6cA-4ccdA:
undetectable		 1k6cA-4ccdA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 10 LEU A 154
VAL A 159
ILE A  86
GLY A  87
GLY A  88
 None
 0.78A 1k6cA-4ccdA:
undetectable		 1k6cA-4ccdA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 6 PRO A 464
PHE A  71
LEU A  67
ILE A  66
 None
 1.14A 1sbrA-4ccdA:
undetectable
1sbrB-4ccdA:
undetectable		 1sbrA-4ccdA:
13.68
1sbrB-4ccdA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 11 LEU A 154
ILE A  86
GLY A  87
GLY A  88
PRO A 148
 None
 0.98A 1sduA-4ccdA:
undetectable		 1sduA-4ccdA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 6 ILE A  42
GLY A  43
ALA A  44
HIS A  80
 None
 0.99A 1wrqA-4ccdA:
undetectable		 1wrqA-4ccdA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 6 ILE A  42
GLY A  43
ALA A  44
HIS A  80
 None
 0.98A 1wrqB-4ccdA:
undetectable		 1wrqB-4ccdA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 GLY A  47
GLU A 114
ASN A 292
 None
 0.71A 1zq9A-4ccdA:
undetectable		 1zq9A-4ccdA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 LEU A 154
VAL A 159
ILE A  86
GLY A  87
GLY A  88
 None
 0.77A 2avsA-4ccdA:
undetectable		 2avsA-4ccdA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 LEU A 154
VAL A 159
ILE A  86
GLY A  87
GLY A  88
 None
 0.87A 2avvD-4ccdA:
undetectable		 2avvD-4ccdA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 6 PHE A 498
SER A 533
GLY A 650
THR A 651
 None
 1.02A 2f7fA-4ccdA:
3.3		 2f7fA-4ccdA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 ARG A 274
GLY A 240
PRO A 239
 None
 0.71A 2hreD-4ccdA:
undetectable		 2hreD-4ccdA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 7 THR A  51
ALA A 322
ASN A 264
PHE A 260
 None
 1.01A 2hzqA-4ccdA:
undetectable		 2hzqA-4ccdA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 TYR A 298
SER A 533
ALA A 492
ALA A 575
GLY A 563
 None
 1.09A 2igtA-4ccdA:
undetectable		 2igtA-4ccdA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 TYR A 298
SER A 533
ALA A 492
ALA A 575
GLY A 563
 None
 1.07A 2igtB-4ccdA:
undetectable		 2igtB-4ccdA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 LEU A 154
VAL A 159
ILE A  86
GLY A  87
GLY A  88
 None
 0.83A 2r5pA-4ccdA:
undetectable		 2r5pA-4ccdA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 LEU A 154
VAL A 159
ILE A  86
GLY A  87
GLY A  88
 None
 0.82A 2r5pC-4ccdA:
undetectable		 2r5pC-4ccdA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		6 / 12 TRP A 135
ASN A 181
GLU A 182
HIS A 237
TYR A 238
GLU A 258
 2DG  A1001 (-4.1A)
2DG  A1001 ( 4.2A)
2DG  A1001 (-3.5A)
None
2DG  A1001 (-4.8A)
2DG  A1001 (-1.6A)
 0.61A 2v3dA-4ccdA:
28.6		 2v3dA-4ccdA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		6 / 12 TRP A 135
ASN A 181
GLU A 182
HIS A 237
TYR A 238
SER A 261
 2DG  A1001 (-4.1A)
2DG  A1001 ( 4.2A)
2DG  A1001 (-3.5A)
None
2DG  A1001 (-4.8A)
2DG  A1001 (-2.6A)
 1.11A 2v3dA-4ccdA:
28.6		 2v3dA-4ccdA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 11 TRP A 135
ASN A 181
GLU A 182
TYR A 238
GLU A 258
 2DG  A1001 (-4.1A)
2DG  A1001 ( 4.2A)
2DG  A1001 (-3.5A)
2DG  A1001 (-4.8A)
2DG  A1001 (-1.6A)
 0.68A 2v3dB-4ccdA:
28.5		 2v3dB-4ccdA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 8 GLY A 577
ILE A 561
MET A 543
ALA A 575
 None
 0.84A 2x0pA-4ccdA:
undetectable		 2x0pA-4ccdA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 TYR A 238
GLU A 182
THR A  93
 2DG  A1001 (-4.8A)
2DG  A1001 (-3.5A)
2DG  A1001 (-3.0A)
 0.69A 2y7hB-4ccdA:
undetectable		 2y7hB-4ccdA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 7 ILE A 368
ILE A 404
LEU A 348
LEU A 342
 None
 0.82A 3adxA-4ccdA:
undetectable		 3adxA-4ccdA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 GLY A  48
GLY A  49
SER A  99
ALA A 525
ASP A 527
 2DG  A1001 (-3.5A)
None
None
None
None
 1.16A 3i5uB-4ccdA:
2.3		 3i5uB-4ccdA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 7 TYR A 109
HIS A 100
MET A 118
VAL A 205
 None
 1.07A 3jwqC-4ccdA:
undetectable		 3jwqC-4ccdA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 GLY A 618
VAL A 545
ALA A 666
ALA A 667
PHE A 623
 None
None
None
NAG  A1542 (-3.6A)
None
 1.06A 3mteB-4ccdA:
undetectable		 3mteB-4ccdA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 GLY A 618
VAL A 545
ALA A 666
ALA A 667
PHE A 623
 None
None
None
NAG  A1542 (-3.6A)
None
 1.08A 3p2kC-4ccdA:
undetectable		 3p2kC-4ccdA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 GLY A 595
ILE A 570
ALA A 528
ALA A 526
ALA A 525
 None
 0.98A 3sudC-4ccdA:
undetectable		 3sudC-4ccdA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 7 TYR A 474
VAL A 664
PHE A 470
PHE A 491
ILE A 649
 None
 1.14A 3zjqA-4ccdA:
undetectable		 3zjqA-4ccdA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 7 TYR A 474
VAL A 664
PHE A 470
PHE A 491
ILE A 649
 None
 1.16A 3zjqB-4ccdA:
undetectable		 3zjqB-4ccdA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC0_A_MIYA1204_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS B FROM
TRANSPOSON TN1 0)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 PHE A  39
HIS A  80
THR A 451
LEU A 453
LEU A 361
 None
None
None
None
NAG  A1364 (-4.4A)
 1.36A 4ac0A-4ccdA:
0.6		 4ac0A-4ccdA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 SER A 316
TYR A  58
PRO A 471
 None
 0.90A 4k8cA-4ccdA:
2.7		 4k8cA-4ccdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 SER A 316
TYR A  58
PRO A 471
 None
 0.88A 4kahA-4ccdA:
2.8		 4kahA-4ccdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 SER A 316
TYR A  58
PRO A 471
 None
 0.88A 4kahB-4ccdA:
undetectable		 4kahB-4ccdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 SER A 316
TYR A  58
PRO A 471
 None
 0.89A 4kanA-4ccdA:
2.8		 4kanA-4ccdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 SER A 316
TYR A  58
PRO A 471
 None
 0.89A 4kanB-4ccdA:
undetectable		 4kanB-4ccdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 SER A 316
TYR A  58
PRO A 471
 None
 0.87A 4kbeA-4ccdA:
undetectable		 4kbeA-4ccdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 SER A 316
TYR A  58
PRO A 471
 None
 0.88A 4kbeB-4ccdA:
undetectable		 4kbeB-4ccdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 GLY A  88
GLU A  97
THR A  96
 None
 0.58A 4kouA-4ccdA:
undetectable		 4kouA-4ccdA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 6 GLU A 182
ARG A 183
GLU A 258
ARG A 380
 2DG  A1001 (-3.5A)
None
2DG  A1001 (-1.6A)
None
 1.45A 4kr3A-4ccdA:
undetectable		 4kr3A-4ccdA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 4 VAL A 388
THR A 370
GLU A 444
GLU A 446
 None
 1.41A 4l78A-4ccdA:
undetectable		 4l78A-4ccdA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 SER A 316
TYR A  58
PRO A 471
 None
 0.91A 4lbgA-4ccdA:
undetectable		 4lbgA-4ccdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 SER A 316
TYR A  58
PRO A 471
 None
 0.89A 4lbgB-4ccdA:
undetectable		 4lbgB-4ccdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJQ_A_27RA401_1
(DNA POLYMERASE III
SUBUNIT BETA)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 5 ARG A  53
TYR A 113
PRO A  98
VAL A 516
 None
 1.18A 4mjqA-4ccdA:
0.0		 4mjqA-4ccdA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 7 PHE A  39
HIS A  80
ILE A  42
ASN A 277
 None
 1.33A 4o7gA-4ccdA:
undetectable
4o7gB-4ccdA:
undetectable		 4o7gA-4ccdA:
15.94
4o7gB-4ccdA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 5 THR A 451
THR A 449
HIS A  80
ASN A  74
 None
 1.30A 4pgfB-4ccdA:
undetectable		 4pgfB-4ccdA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 LEU A 357
ALA A 356
LEU A  35
GLY A 399
LEU A 397
 None
 0.90A 4pxmA-4ccdA:
undetectable		 4pxmA-4ccdA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 8 TYR A 158
PHE A 137
GLY A 178
ILE A 207
 None
 0.94A 4qoiA-4ccdA:
undetectable
4qoiB-4ccdA:
undetectable		 4qoiA-4ccdA:
16.90
4qoiB-4ccdA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 ASP A  89
GLY A  95
ALA A  50
GLU A 114
PHE A 498
 None
 1.20A 4xe5A-4ccdA:
undetectable		 4xe5A-4ccdA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 11 LEU A 293
LEU A  55
LEU A 130
LEU A  82
LEU A 172
 None
 1.00A 4zowA-4ccdA:
undetectable		 4zowA-4ccdA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 11 LEU A 357
ALA A 356
LEU A  35
GLY A 399
LEU A 397
 None
 0.91A 5dxgB-4ccdA:
undetectable		 5dxgB-4ccdA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 TRP A 214
ILE A 217
SER A 210
 None
 0.97A 5gqbA-4ccdA:
10.7		 5gqbA-4ccdA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 LEU A 357
ALA A 356
LEU A  35
GLY A 399
LEU A 397
 None
 0.94A 5gs4A-4ccdA:
undetectable		 5gs4A-4ccdA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 LEU A 357
ALA A 356
LEU A  35
GLY A 399
LEU A 397
 None
 0.96A 5gtrA-4ccdA:
undetectable		 5gtrA-4ccdA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 ALA A  44
ASP A 175
GLY A 132
SER A  46
GLU A 114
 None
 1.21A 5hfjG-4ccdA:
2.2		 5hfjG-4ccdA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA612_1
(PHIAB6 TAILSPIKE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 4 VAL A 294
THR A  51
GLU A  85
GLU A 114
 None
 1.42A 5jsdA-4ccdA:
1.9
5jsdB-4ccdA:
0.7		 5jsdA-4ccdA:
21.30
5jsdB-4ccdA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 4 GLU A  85
GLU A 114
VAL A 294
THR A  51
 None
 1.42A 5jsdA-4ccdA:
1.9
5jsdC-4ccdA:
0.7		 5jsdA-4ccdA:
21.30
5jsdC-4ccdA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 VAL A  45
SER A  46
TRP A 291
 None
None
2DG  A1001 ( 3.7A)
 1.00A 5jwaA-4ccdA:
undetectable		 5jwaA-4ccdA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 TYR A 298
SER A 296
TRP A 315
 None
 1.08A 5n8jB-4ccdA:
2.0		 5n8jB-4ccdA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 TYR A 298
SER A 296
TRP A 315
 None
 1.02A 5n8jA-4ccdA:
undetectable		 5n8jA-4ccdA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		3 / 3 TYR A 298
SER A 296
TRP A 315
 None
 1.00A 5n8jD-4ccdA:
2.1		 5n8jD-4ccdA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 4 VAL A 345
VAL A 355
TYR A 280
GLN A 278
 None
 1.20A 5qggA-4ccdA:
undetectable		 5qggA-4ccdA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 4 VAL A 345
VAL A 355
TYR A 280
GLN A 278
 None
 1.23A 5qgoA-4ccdA:
undetectable		 5qgoA-4ccdA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 4 VAL A 345
VAL A 355
TYR A 280
GLN A 278
 None
 1.21A 5qgpA-4ccdA:
undetectable		 5qgpA-4ccdA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 4 VAL A 345
VAL A 355
TYR A 280
GLN A 278
 None
 1.13A 5qgqA-4ccdA:
undetectable		 5qgqA-4ccdA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 4 VAL A 345
VAL A 355
TYR A 280
GLN A 278
 None
 1.17A 5qhbA-4ccdA:
undetectable		 5qhbA-4ccdA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_B_SALB504_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 6 SER A 530
HIS A 652
PHE A 583
THR A 591
 None
 1.37A 5u6nB-4ccdA:
undetectable		 5u6nB-4ccdA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 7 SER A 136
GLY A  49
ALA A  50
VAL A  56
 None
 0.84A 6dwnB-4ccdA:
undetectable		 6dwnB-4ccdA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		4 / 5 GLN A 391
THR A 449
HIS A 330
GLY A 352
 None
 1.05A 6gbnC-4ccdA:
undetectable		 6gbnC-4ccdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 4ccd GALACTOCEREBROSIDASE
(Mus
musculus) 		5 / 12 VAL A 534
PHE A 579
ILE A 532
ASN A 566
ILE A 572
 None
 1.25A 6gsdA-4ccdA:
3.0		 6gsdA-4ccdA:
9.75