SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ccl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		4 / 8 GLY A 307
ASN A  87
GLY A 308
VAL A  83
 None
 0.82A 1dbbH-4cclA:
undetectable
1dbbL-4cclA:
undetectable		 1dbbH-4cclA:
18.67
1dbbL-4cclA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		4 / 7 GLY A 120
LEU A 192
ALA A 191
TYR A 190
 None
 0.77A 1dmaA-4cclA:
undetectable		 1dmaA-4cclA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		3 / 3 LEU A  81
LEU A  53
SER A  64
 None
 0.55A 1tlmA-4cclA:
undetectable		 1tlmA-4cclA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		5 / 11 PHE A  31
ASN A 197
SER A 114
ILE A 113
ILE A 134
 None
None
SO4  A1375 (-2.5A)
None
None
 1.27A 2blaA-4cclA:
undetectable		 2blaA-4cclA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		4 / 5 LEU A 312
ALA A 320
TRP A 369
LEU A 309
 None
 0.86A 2oaxA-4cclA:
undetectable		 2oaxA-4cclA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_A_CTCA1385_0
(TETX2 PROTEIN)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		5 / 10 GLN A 135
ASN A 194
GLY A 136
GLY A 121
MET A 112
 None
None
None
None
SO4  A1375 (-4.5A)
 1.01A 2y6rA-4cclA:
0.0		 2y6rA-4cclA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		4 / 4 LEU A  43
GLY A  42
LEU A  40
GLU A  39
 None
 1.06A 3tgvB-4cclA:
undetectable		 3tgvB-4cclA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		5 / 11 PHE A  28
ASN A  30
GLY A 176
PRO A  34
ALA A  95
 None
 1.33A 4a6nA-4cclA:
undetectable		 4a6nA-4cclA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_A_MIYA391_1
(TETX2 PROTEIN)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		5 / 10 GLN A 135
ASN A 194
GLY A 136
GLY A 121
MET A 112
 None
None
None
None
SO4  A1375 (-4.5A)
 1.05A 4a99A-4cclA:
undetectable		 4a99A-4cclA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_B_MIYB391_1
(TETX2 PROTEIN)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		5 / 11 GLN A 135
ASN A 194
GLY A 136
GLY A 121
MET A 112
 None
None
None
None
SO4  A1375 (-4.5A)
 1.06A 4a99B-4cclA:
undetectable		 4a99B-4cclA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC391_1
(TETX2 PROTEIN)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		5 / 11 GLN A 135
ASN A 194
GLY A 136
GLY A 121
MET A 112
 None
None
None
None
SO4  A1375 (-4.5A)
 1.07A 4a99C-4cclA:
undetectable		 4a99C-4cclA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD391_1
(TETX2 PROTEIN)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		5 / 11 GLN A 135
ASN A 194
GLY A 136
GLY A 121
MET A 112
 None
None
None
None
SO4  A1375 (-4.5A)
 1.06A 4a99D-4cclA:
undetectable		 4a99D-4cclA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		5 / 9 GLY A 322
PRO A 205
GLU A 209
GLY A 213
TYR A 217
 None
 1.44A 4fimA-4cclA:
undetectable		 4fimA-4cclA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 4ccl 50S RIBOSOMAL
PROTEIN L16 ARGININE
HYDROXYLASE
(Escherichia
coli) 		3 / 3 ASP A 326
GLU A 262
SER A 366
 None
 0.84A 5bw4B-4cclA:
undetectable		 5bw4B-4cclA:
21.12