SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ce7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		3 / 3 TRP A 200
ALA A 193
VAL A 215
 None
 0.89A 1bdwA-4ce7A:
undetectable
1bdwB-4ce7A:
undetectable		 1bdwA-4ce7A:
5.53
1bdwB-4ce7A:
5.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		4 / 8 GLU A  33
ALA A  28
ALA A  57
THR A  61
 None
 0.94A 1ie4B-4ce7A:
undetectable
1ie4D-4ce7A:
undetectable		 1ie4B-4ce7A:
16.99
1ie4D-4ce7A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		4 / 6 PHE A 192
VAL A 224
LEU A 228
SER A 254
 None
 0.89A 1wrlB-4ce7A:
undetectable		 1wrlB-4ce7A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		3 / 3 TRP A  31
THR A 348
TYR A  50
 None
 1.10A 2a3aB-4ce7A:
undetectable		 2a3aB-4ce7A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		5 / 11 LEU A 191
ILE A 256
HIS A 287
LEU A 291
GLY A 226
 None
 0.92A 2bxmA-4ce7A:
undetectable		 2bxmA-4ce7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		5 / 12 GLY A 355
ALA A 354
GLY A  53
VAL A  54
VAL A 325
 None
 0.97A 2f8gA-4ce7A:
undetectable		 2f8gA-4ce7A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		5 / 12 THR A  52
TYR A  51
GLY A 347
GLY A 349
GLY A 326
 None
 0.97A 2fk8A-4ce7A:
undetectable		 2fk8A-4ce7A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PK4_A_ACAA100_1
(HUMAN PLASMINOGEN
KRINGLE 4)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		4 / 7 ASP A  89
TRP A  45
PHE A 346
ARG A 219
 None
 1.28A 2pk4A-4ce7A:
undetectable		 2pk4A-4ce7A:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		5 / 12 ALA A 307
PRO A 306
VAL A 308
ILE A 300
ASP A 301
 None
 1.07A 2v95A-4ce7A:
undetectable		 2v95A-4ce7A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		4 / 5 LEU A 231
ARG A 219
TRP A 146
TYR A  95
 None
 1.50A 2zlcA-4ce7A:
undetectable		 2zlcA-4ce7A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		5 / 11 ASN A 103
LEU A 159
VAL A 156
LEU A 230
THR A 115
 None
 1.32A 3fl9C-4ce7A:
undetectable		 3fl9C-4ce7A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		3 / 3 PRO A 337
SER A 339
ASN A 330
 None
 0.93A 3lslG-4ce7A:
undetectable		 3lslG-4ce7A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		5 / 10 GLY A 355
ALA A 354
GLY A  53
VAL A  54
VAL A 325
 None
 0.99A 3oxwC-4ce7A:
undetectable		 3oxwC-4ce7A:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		5 / 12 GLY A 355
ALA A 354
GLY A  53
VAL A  54
VAL A 325
 None
 1.01A 3oxxC-4ce7A:
undetectable		 3oxxC-4ce7A:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		5 / 12 GLY A 349
VAL A 281
GLY A  48
ALA A  49
ARG A 219
 None
 1.09A 3sugA-4ce7A:
undetectable		 3sugA-4ce7A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		3 / 3 LEU A 119
LYS A 116
THR A 115
 None
 0.56A 4lj0A-4ce7A:
undetectable		 4lj0A-4ce7A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_B_3QBB203_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		5 / 11 ARG A 324
ASP A 341
HIS A 320
TRP A 312
PHE A 351
 None
 1.40A 4wh5A-4ce7A:
0.0
4wh5B-4ce7A:
0.0		 4wh5A-4ce7A:
22.68
4wh5B-4ce7A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		4 / 7 VAL A 281
SER A 282
ALA A 285
GLY A 349
 None
 0.89A 5fpdA-4ce7A:
undetectable		 5fpdA-4ce7A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		5 / 12 THR A  52
GLY A 226
VAL A 224
PHE A 286
LEU A 353
 None
 1.02A 5jo9A-4ce7A:
undetectable		 5jo9A-4ce7A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4ce7 UNSATURATED
3S-RHAMNOGLYCURONYL
HYDROLASE
(Nonlabens
ulvanivorans) 		5 / 12 LEU A 352
ILE A  26
LEU A  70
ALA A  69
TYR A  99
 None
 1.24A 6djzA-4ce7A:
undetectable		 6djzA-4ce7A:
20.05