SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cfi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 4cfi FLAGELLIN
(Burkholderia
pseudomallei) 		5 / 12 LEU A  81
LEU A 319
ALA A  77
ILE A 136
ILE A 169
 None
 1.06A 1tw4A-4cfiA:
undetectable		 1tw4A-4cfiA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 4cfi FLAGELLIN
(Burkholderia
pseudomallei) 		5 / 11 PHE A 250
GLY A 170
GLY A 171
GLY A 172
ALA A 308
 None
 0.86A 4l8fB-4cfiA:
undetectable		 4l8fB-4cfiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 4cfi FLAGELLIN
(Burkholderia
pseudomallei) 		5 / 11 PHE A 250
GLY A 170
GLY A 171
GLY A 172
ALA A 308
 None
 0.85A 4l8fD-4cfiA:
undetectable		 4l8fD-4cfiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 4cfi FLAGELLIN
(Burkholderia
pseudomallei) 		5 / 12 GLN A 300
LEU A 290
GLY A 172
ASN A 282
ALA A 245
 None
 1.37A 4pclB-4cfiA:
undetectable		 4pclB-4cfiA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 4cfi FLAGELLIN
(Burkholderia
pseudomallei) 		5 / 12 ALA A 259
THR A 239
PHE A 218
ILE A 206
PHE A 235
 None
 1.39A 5hgcA-4cfiA:
undetectable		 5hgcA-4cfiA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 4cfi FLAGELLIN
(Burkholderia
pseudomallei) 		5 / 10 PRO A 102
ALA A  98
GLY A 297
ILE A 292
ALA A 108
 None
 1.11A 5vyhA-4cfiA:
undetectable		 5vyhA-4cfiA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 4cfi FLAGELLIN
(Burkholderia
pseudomallei) 		5 / 12 ALA A  77
GLY A  80
SER A  79
LEU A  74
LEU A 144
 None
 1.15A 5w7pA-4cfiA:
undetectable		 5w7pA-4cfiA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 4cfi FLAGELLIN
(Burkholderia
pseudomallei) 		4 / 4 ALA A  95
ALA A  98
ALA A 298
ALA A 301
 None
 0.57A 6gtqA-4cfiA:
0.0
6gtqB-4cfiA:
0.0		 6gtqA-4cfiA:
23.05
6gtqB-4cfiA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 4cfi FLAGELLIN
(Burkholderia
pseudomallei) 		4 / 4 ALA A 298
ALA A 301
ALA A  95
ALA A  98
 None
 0.57A 6gtqA-4cfiA:
0.0
6gtqB-4cfiA:
0.0		 6gtqA-4cfiA:
23.05
6gtqB-4cfiA:
23.05