SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cge'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 4cge RESUSCITATION-PROMOT
ING FACTOR RPFE
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 146
TRP A 113
ILE A 150
 None
 0.92A 4mwxA-4cgeA:
undetectable		 4mwxA-4cgeA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4cge RESUSCITATION-PROMOT
ING FACTOR RPFE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 125
ALA A 105
ASN A 100
ALA A 153
ILE A 162
 None
 1.06A 5eypB-4cgeA:
undetectable		 5eypB-4cgeA:
13.06