SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4cgu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 4cgu PROTEIN INTERACTING
WITH HSP90 1
(Saccharomyces
cerevisiae) 		3 / 3 PRO B 265
ASN B 287
ARG B 338
 PRO  B 265 ( 1.1A)
ASN  B 287 ( 0.6A)
ARG  B 338 ( 0.6A)
 1.01A 2qeuB-4cguB:
undetectable		 2qeuB-4cguB:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 4cgu PROTEIN INTERACTING
WITH HSP90 1
(Saccharomyces
cerevisiae) 		4 / 7 PRO B 299
ILE B 329
ILE B 342
ILE B 316
 PRO  B 299 ( 1.1A)
ILE  B 329 ( 0.7A)
ILE  B 342 ( 0.6A)
ILE  B 316 ( 0.7A)
 0.94A 5murB-4cguB:
undetectable		 5murB-4cguB:
19.42