SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ch7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4ch7 NIRD-LIKE PROTEIN
(Hydrogenobacter
thermophilus) 		5 / 12 ILE A 175
LEU A 205
LEU A 197
ALA A 194
LEU A 217
 None
 0.96A 1xlsA-4ch7A:
undetectable		 1xlsA-4ch7A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4ch7 NIRD-LIKE PROTEIN
(Hydrogenobacter
thermophilus) 		5 / 12 ILE A 175
LEU A 205
LEU A 197
ALA A 194
LEU A 217
 None
 0.96A 1xlsB-4ch7A:
undetectable		 1xlsB-4ch7A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4ch7 NIRD-LIKE PROTEIN
(Hydrogenobacter
thermophilus) 		5 / 12 ILE A 175
LEU A 205
LEU A 197
ALA A 194
LEU A 217
 None
 0.96A 1xlsC-4ch7A:
undetectable		 1xlsC-4ch7A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4ch7 NIRD-LIKE PROTEIN
(Hydrogenobacter
thermophilus) 		5 / 12 SER A 268
LEU A 306
VAL A 238
PHE A 101
ALA A  70
 None
 1.34A 3u9fG-4ch7A:
undetectable
3u9fH-4ch7A:
undetectable		 3u9fG-4ch7A:
19.94
3u9fH-4ch7A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4ch7 NIRD-LIKE PROTEIN
(Hydrogenobacter
thermophilus) 		5 / 11 ILE A 175
LEU A 205
LEU A 197
ALA A 194
LEU A 217
 None
 0.94A 5ji0A-4ch7A:
undetectable		 5ji0A-4ch7A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4ch7 NIRD-LIKE PROTEIN
(Hydrogenobacter
thermophilus) 		5 / 12 ILE A 175
LEU A 205
LEU A 197
ALA A 194
LEU A 217
 None
 0.88A 5z12B-4ch7A:
undetectable		 5z12B-4ch7A:
12.63