SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4chj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZJQ_A_NCAA300_0 (PROTOGLOBIN)	4chj	IMC SUB-COMPARTMENT PROTEIN ISP3 (Toxoplasma gondii)	4 / 7	PHE A 131 VAL A 116 PHE A 118 ILE A 85	None	0.88A	3zjqA-4chjA: undetectable	3zjqA-4chjA: 21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZJQ_B_NCAB300_0 (PROTOGLOBIN)	4chj	IMC SUB-COMPARTMENT PROTEIN ISP3 (Toxoplasma gondii)	4 / 7	PHE A 131 VAL A 116 PHE A 118 ILE A 85	None	0.90A	3zjqB-4chjA: undetectable	3zjqB-4chjA: 21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DRI_A_RAPA201_2 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5 SERINE/THREONINE-PRO TEIN KINASE MTOR)	4chj	IMC SUB-COMPARTMENT PROTEIN ISP3 (Toxoplasma gondii)	5 / 10	LEU A 144 GLU A 147 THR A 135 ASP A 136 PHE A 143	None	1.31A	4driB-4chjA: undetectable	4driB-4chjA: 23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KIR_B_RCXB601_2 (PROSTAGLANDIN G/H SYNTHASE 2)	4chj	IMC SUB-COMPARTMENT PROTEIN ISP3 (Toxoplasma gondii)	4 / 4	LEU A 144 ARG A 119 ILE A 90 PHE A 118	None	1.33A	5kirB-4chjA: 1.3	5kirB-4chjA: 14.66

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ZJQ_A_NCAA300_0","PROTOGLOBIN","4chj","IMC SUB-COMPARTMENT PROTEIN ISP3","Toxoplasma gondii",4,"PHE A 131;VAL A 116;PHE A 118;ILE A  85","None","0.88A","3zjqA-4chjA:undetectable","3zjqA-4chjA:21.80"],["3ZJQ_B_NCAB300_0","PROTOGLOBIN","4chj","IMC SUB-COMPARTMENT PROTEIN ISP3","Toxoplasma gondii",4,"PHE A 131;VAL A 116;PHE A 118;ILE A  85","None","0.90A","3zjqB-4chjA:undetectable","3zjqB-4chjA:21.80"],["4DRI_A_RAPA201_2","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5;SERINE\/THREONINE-PROTEIN KINASE MTOR","4chj","IMC SUB-COMPARTMENT PROTEIN ISP3","Toxoplasma gondii",5,"LEU A 144;GLU A 147;THR A 135;ASP A 136;PHE A 143","None","1.31A","4driB-4chjA:undetectable","4driB-4chjA:23.33"],["5KIR_B_RCXB601_2","PROSTAGLANDIN G\/H SYNTHASE 2","4chj","IMC SUB-COMPARTMENT PROTEIN ISP3","Toxoplasma gondii",4,"LEU A 144;ARG A 119;ILE A  90;PHE A 118","None","1.33A","5kirB-4chjA:1.3","5kirB-4chjA:14.66"]]