SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4chu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 4chu HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ISCR
(Escherichia
coli) 		4 / 5 LEU A  39
GLN A  44
LEU A  42
GLU A  43
 None
 1.05A 3h5gA-4chuA:
undetectable
3h5gB-4chuA:
undetectable		 3h5gA-4chuA:
9.20
3h5gB-4chuA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 4chu HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ISCR
(Escherichia
coli) 		3 / 3 SER A  73
ALA A  75
VAL A  76
 None
 0.58A 4o2bA-4chuA:
undetectable		 4o2bA-4chuA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4chu HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ISCR
(Escherichia
coli) 		3 / 3 SER A  73
ALA A  75
VAL A  76
 None
 0.51A 4x1iA-4chuA:
undetectable		 4x1iA-4chuA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4chu HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ISCR
(Escherichia
coli) 		3 / 3 SER A  73
ALA A  75
VAL A  76
 None
 0.44A 5eypA-4chuA:
undetectable		 5eypA-4chuA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 4chu HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ISCR
(Escherichia
coli) 		5 / 12 LEU A  15
ALA A  18
VAL A  17
PHE A  46
ALA A  10
 None
 1.05A 5n5dB-4chuA:
undetectable		 5n5dB-4chuA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 4chu HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ISCR
(Escherichia
coli) 		3 / 3 SER A  73
ALA A  75
VAL A  76
 None
 0.49A 5xiwC-4chuA:
undetectable		 5xiwC-4chuA:
18.54